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Synthesis, biological evaluation and structure-activity relationship of novel dichloroacetophenones targeting pyruvate dehydrogenase kinases with potent anticancer activity Journal article
European Journal of Medicinal Chemistry, 2021,Volume: 214
Authors:  Xu,Biao;  Wang,Zhi Peng;  Liu,Qingwang;  Yang,Xiaohong;  Li,Xuemin;  Huang,Ding;  Qiu,Yanfei;  Tam,Kin Yip;  Zhang,Shao Lin;  He,Yun
Favorite |  | TC[WOS]:0 TC[Scopus]:0 | Submit date:2021/03/04
Cancer metabolism  Proliferation  Pyruvate dehydrogenase kinase  Structure-activity relationship  
Development of dual inhibitors targeting pyruvate dehydrogenase kinases and human lactate dehydrogenase A: High-throughput virtual screening, synthesis and biological validation Journal article
European Journal of Medicinal Chemistry, 2020,Volume: 203
Authors:  Xiang,Sichuan;  Huang,Ding;  He,Qiaolin;  Li,Jie;  Tam,Kin Yip;  Zhang,Shao Lin;  He,Yun
Favorite |  | TC[WOS]:2 TC[Scopus]:2 | Submit date:2021/03/04
Cancer metabolism  Cancer proliferation  Dual inhibitor  Lactate dehydrogenase A  Pyruvate dehydrogenase kinase  
Engineering a microcarrier based on a polysaccharide-growth factor complex for enhancing the proliferation of mesenchymal stem cells Journal article
International Journal of Biological Macromolecules, 2020,Volume: 155,Page: 911-918
Authors:  Niu,Yiming;  Zhang,Yuhan;  He,Wei;  Xing,Panfei;  Dong,Lei;  Li,Qiu;  Wang,Chunming
Favorite |  | TC[WOS]:0 TC[Scopus]:0 | Submit date:2021/03/02
Eucommia ulmoides  Mesenchymal stem cells  Microcarrier  PDGF-BB  Proliferation  
Exosomes derived from normal human bronchial epithelial cells down-regulate proliferation and migration of hydroquinone-transformed malignant recipient cells via up-regulating PTEN expression Journal article
Chemosphere, 2020,Volume: 244
Authors:  Lian,Zhenwei;  Hu,Zuqing;  Xian,Hongyi;  Jiang,Ran;  Huang,Haoyu;  Jiang,Yunxia;  Zheng,Zhongdaixi;  Lloyd,R. Stephen;  Yuan,Jianhui;  Sha,Yan;  Wang,Sanming;  Hu,Dalin
Favorite |  | TC[WOS]:1 TC[Scopus]:1 | Submit date:2021/03/02
Benzene  Exosomes  Migration  Proliferation  PTEN  Toxicity  
Ethanol extract of Ophiorrhiza pumila suppresses liver cancer cell proliferation and migration Journal article
Chinese Medicine (United Kingdom), 2020,Volume: 15,Issue: 1
Authors:  Liu,Hui;  Liao,Wanqin;  Fan,Lixia;  Zheng,Zhaoguang;  Liu,Dahai;  Zhang,Qing Wen;  Yang,Anping;  Liu,Fang
Favorite |  | TC[WOS]:3 TC[Scopus]:3 | Submit date:2021/03/02
Apoptosis  Liver cancer  Migration  Ophiorrhiza pumila  Proliferation  
DNA replication licensing proteins: Saints and sinners in cancer Journal article
Seminars in Cancer Biology, 2019,Volume: 58,Page: 11-21
Authors:  Mughal,Muhammad Jameel;  Mahadevappa,Ravikiran;  Kwok,Hang Fai
Favorite |  | TC[WOS]:7 TC[Scopus]:7 | Submit date:2021/03/04
Cancer  DNA replication  Licensing proteins  Pre-replication complex  Proliferation  
Upregulation of phosphoserine phosphatase contributes to tumor progression and predicts poor prognosis in non-small cell lung cancer patients Journal article
THORACIC CANCER, 2019,Volume: 10,Issue: 5,Page: 1203-1212
Authors:  Li Liao;  Huajian Yu;  Mengxi Ge;  Qiong Zhan;  Ruofan Huang;  Xiaoyu Ji;  Xiaohua Liang;  Xinli Zhou
Favorite |  | TC[WOS]:3 TC[Scopus]:3 | Submit date:2020/03/10
Akt/ampk Signaling Pathway  Metastasis  Nsclc  Proliferation  Psph  
DNA replication licensing protein MCM10 promotes tumor progression and is a novel prognostic biomarker and potential therapeutic target in breast cancer Journal article
Cancers, 2018,Volume: 10,Issue: 9
Authors:  Mahadevappa R.;  Neves H.;  Yuen S.M.;  Jameel M.;  Bai Y.;  Yuen H.-F.;  Zhang S.-D.;  Zhu Y.;  Lin Y.;  Kwok H.F.
Favorite |  | TC[WOS]:11 TC[Scopus]:11 | Submit date:2018/12/19
Breast Cancer  Knockdown  Mcm10  Overexpression  Proliferation  Survival  
Deficiency in Fpr2 results in reduced numbers of Lin(-)cKit(+)Sca1(+) myeloid progenitor cells Journal article
JOURNAL OF BIOLOGICAL CHEMISTRY, 2018,Volume: 293,Issue: 35,Page: 13452-13463
Authors:  Chen, Keqiang;  Singh, Vijay K.;  Tang, Peng;  Bao, Zhiyao;  He, Tianzhen;  Xiang, Yi;  Gong, Wanghua;  Yoshimura, Teizo;  Le, Yingying;  Tessarollo, Lino;  Chen, Xin;  Wang, Ji Ming
Favorite |  | TC[WOS]:5 TC[Scopus]:4 | Submit date:2018/10/30
Mouse  Bone Marrow  Myeloid Cell  Proliferation  Cytokine  C-kit  Fpr2  Lin(-)C-kit(+)Sca1(+)Cells  Scf  
The p38 MAPK inhibitor SB203580 abrogates tumor necrosis factor-induced proliferative expansion of mouse CD4+Foxp3+ regulatory T cells Journal article
Frontiers in Immunology, 2018,Volume: 9,Issue: JUL
Authors:  He T.;  Liu S.;  Chen S.;  Ye J.;  Wu X.;  Bian Z.;  Chen X.
Favorite |  | TC[WOS]:7 TC[Scopus]:9 | Submit date:2018/11/06
cd4+foxp3+ Regulatory t Cells  P38 Mapk  Proliferation  Tnf Receptor Type Ii  Tumor Necrosis Factor