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9R, the cholinesterase and amyloid beta aggregation dual inhibitor, as a multifunctional agent to improve cognitive deficit and neuropathology in the triple-transgenic Alzheimer's disease mouse model Journal article
Neuropharmacology, 2020,Volume: 181
Authors:  Ju,Yaojun;  Tam,Kin Yip
Favorite |  | TC[WOS]:1 TC[Scopus]:1 | Submit date:2021/03/04
Alzheimer's disease  Amyloid beta  Cholinesterase  Dual inhibition  Multifunction  
An Isoquinolinium Dual Inhibitor of Cholinesterases and Amyloid β Aggregation Mitigates Neuropathological Changes in a Triple-Transgenic Mouse Model of Alzheimer's Disease Journal article
ACS Chemical Neuroscience, 2020,Volume: 11,Issue: 20,Page: 3346-3357
Authors:  Ju,Yaojun;  Chakravarty,Harapriya;  Tam,Kin Yip
Favorite |  | TC[WOS]:0 TC[Scopus]:0 | Submit date:2021/03/04
Alzheimer's disease  amyloid beta  cholinesterase  dual inhibition  
Dual targeting of cholinesterase and amyloid beta with pyridinium/isoquinolium derivatives Journal article
Drug Development Research, 2020,Volume: 81,Issue: 2,Page: 242-255
Authors:  Chakravarty,Harapriya;  Ju,Yaojun;  Chen,Wen Hua;  Tam,Kin Y.
Favorite |  | TC[WOS]:4 TC[Scopus]:4 | Submit date:2021/03/04
acetylcholinesterase  Alzheimer's disease  amyloid beta  butyrylcholinesterase  dual target inhibitor  isoquinolinium  pyridinium  
Fish oil protects the blood-brain barrier integrity in a mouse model of Alzheimer's disease Journal article
Chinese Medicine (United Kingdom), 2020,Volume: 15,Issue: 1
Authors:  Xie,Youna;  Yan,Lingli;  Zeng,Haitao;  Chen,Weineng;  Lu,Jia Hong;  Wan,Jian Bo;  Su,Huanxing;  Yao,Xiaoli
Favorite |  | TC[WOS]:2 TC[Scopus]:2 | Submit date:2021/03/01
Amyloid beta  Aβ-degrading enzymes  Neuroinflammation  NF-κB  Omega-3 polyunsaturated fatty acids  
Omega-3 polyunsaturated fatty acids promote brain-to-blood clearance of β-Amyloid in a mouse model with Alzheimer's disease Journal article
Brain, Behavior, and Immunity, 2020,Volume: 85,Page: 35-45
Authors:  Yan,Lingli;  Xie,Youna;  Satyanarayanan,Senthil Kumaran;  Zeng,Haitao;  Liu,Qiang;  Huang,Miaodan;  Ma,Yuemeng;  Wan,Jian Bo;  Yao,Xiaoli;  Su,Kuan Pin;  Su,Huanxing
Favorite |  | TC[WOS]:10 TC[Scopus]:12 | Submit date:2021/03/01
Alzheimer's disease  beta-Amyloid  Low-density lipoprotein receptor-related protein 1  Neuroinflammation  Omega-3 polyunsaturated fatty acids  
A small molecule transcription factor EB activator ameliorates beta-amyloid precursor protein and Tau pathology in Alzheimer's disease models Journal article
Aging Cell, 2020,Volume: 19,Issue: 2
Authors:  Song,Ju Xian;  Malampati,Sandeep;  Zeng,Yu;  Durairajan,Siva Sundara Kumar;  Yang,Chuan Bin;  Tong,Benjamin Chun Kit;  Iyaswamy,Ashok;  Shang,Wen Bin;  Sreenivasmurthy,Sravan Gopalkrishnashetty;  Zhu,Zhou;  Cheung,King Ho;  Lu,Jia Hong;  Tang,Chunzhi;  Xu,Nenggui;  Li,Min
Favorite |  | TC[WOS]:21 TC[Scopus]:20 | Submit date:2021/03/02
Alzheimer's disease  beta-amyloid  curcumin analog C1  MAPT/Tau  TFEB  
Artemisinin improved neuronal functions in Alzheimer's disease animal model 3xtg mice and neuronal cells via stimulating the ERK/CREB signaling pathway Journal article
Aging and Disease, 2020,Volume: 11,Issue: 4,Page: 801-819
Authors:  Zhao,Xia;  Li,Shuai;  Gaur,Uma;  Zheng,Wenhua
Favorite |  | TC[WOS]:3 TC[Scopus]:5 | Submit date:2021/03/04
3×Tg mice  Alzheimer's disease  Amyloid beta  Artemisinin  Cognitive behavior  SH-SY5Ycells  
A reciprocal relationship between reactive oxygen species and mitochondrial dynamics in neurodegeneration Journal article
REDOX BIOLOGY, 2018,Volume: 14,Page: 7-19
Authors:  Hung, Clara Hiu-Ling;  Cheng, Sally Shuk-Yee;  Cheung, Yuen-Ting;  Wuwongse, Suthicha;  Zhang, Natalie Qishan;  Ho, Yuen-Shan;  Lee, Simon Ming-Yuen;  Chang, Raymond Chuen-Chung
Favorite |  | TC[WOS]:54 TC[Scopus]:58 | Submit date:2018/10/30
Alzheimer's Disease  Beta-amyloid  Mitochondria  Fission And Fusion  Drp-1  Neurodegeneration  
SLOH, a carbazole-based fluorophore, mitigates neuropathology and behavioral impairment in the triple-transgenic mouse model of Alzheimer's disease Journal article
NEUROPHARMACOLOGY, 2018,Volume: 131,Page: 351-363
Authors:  Wu, Xiaoli;  Kosaraju, Jayasankar;  Zhou, Wei;  Tam, Kin Yip
Favorite |  | TC[WOS]:9 TC[Scopus]:9 | Submit date:2018/10/31
Amyloid beta  Aggregation  Alzheimer's disease  3xTg-AD  Neuroprotection  SH-SY5Y  
Human amyloid beta peptide and tau co-expression impairs behavior and causes specific gene expression changes in Caenorhabditis elegans Journal article
NEUROBIOLOGY OF DISEASE, 2018,Volume: 109,Page: 88-101
Authors:  Wang, Chenyin;  Saar, Valeria;  Leung, Ka Lai;  Chen, Liang;  Wong, Garry
Favorite |  | TC[WOS]:19 TC[Scopus]:18 | Submit date:2018/10/30
Caenorhabditis elegans  Alzheimer's disease  Transcriptome analysis  Amyloid beta  Tau  RNA interference