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The role of FOXOs and autophagy in cancer and metastasis—Implications in therapeutic development Journal article
Medicinal Research Reviews, 2020,Volume: 40,Issue: 6,Page: 2089-2113
Authors:  Farhan,Mohd;  Silva,Marta;  Li,Shuai;  Yan,Fengxia;  Fang,Jiankang;  Peng,Tangming;  Hu,Jim;  Tsao,Ming Sound;  Little,Peter;  Zheng,Wenhua
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autophagy  cancer  FOXO proteins  metastasis  
Artemisinin protects motoneurons against axotomy-induced apoptosis through activation of the PKA-Akt signaling pathway and promotes neural stem/progenitor cells differentiation into NeuN+ neurons Journal article
Pharmacological Research, 2020,Volume: 159
Authors:  Liu,Linlin;  Zhao,Xia;  Silva,Marta;  Li,Shuai;  Xing,Xingan;  Zheng,Wenhua
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Artemisinin  Brachial plexus axotomy  Inflammatory response  Motoneurons  
PHLDA1 promotes microglia-mediated neuroinflammation via regulating K63-linked ubiquitination of TRAF6 Journal article
Brain, Behavior, and Immunity, 2020,Volume: 88,Page: 640-653
Authors:  Han,Chaojun;  Yan,Pengju;  He,Tao;  Cheng,Junjie;  Zheng,Wenhua;  Zheng,Long Tai;  Zhen,Xuechu
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Dopaminergic neuron  Microglia  Neuroinflammation  NF-κB  PHLDA1  TRAF6  Ubiquitination  
Role of FOXO Transcription Factors in Cancer Metabolism and Angiogenesis Journal article
Cells, 2020,Volume: 9,Issue: 7
Authors:  Farhan,Mohd;  Silva,Marta;  Xingan,Xing;  Huang,Yu;  Zheng,Wenhua
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angiogenesis  cancer  cancer metabolism  FOXOs  
Pristimerin-induced uveal melanoma cell death via inhibiting PI3K/Akt/FoxO3a signalling pathway Journal article
Journal of Cellular and Molecular Medicine, 2020,Volume: 24,Issue: 11,Page: 6208-6219
Authors:  Yan,Fengxia;  Liao,Rifang;  Silva,Marta;  Li,Shuai;  Jiang,Yizhou;  Peng,Tangming;  Lazarovici,Philip;  Zheng,Wenhua
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cell death  FoxO3a  nuclear accumulation  Pristimerin  uveal melanoma  
Protective Effect of Metformin against Hydrogen Peroxide-Induced Oxidative Damage in Human Retinal Pigment Epithelial (RPE) Cells by Enhancing Autophagy through Activation of AMPK Pathway Journal article
Oxidative Medicine and Cellular Longevity, 2020,Volume: 2020
Authors:  Zhao,Xia;  Liu,Linlin;  Jiang,Yizhou;  Silva,Marta;  Zhen,Xuechu;  Zheng,Wenhua
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Artemisinin improved neuronal functions in Alzheimer's disease animal model 3xtg mice and neuronal cells via stimulating the ERK/CREB signaling pathway Journal article
Aging and Disease, 2020,Volume: 11,Issue: 4,Page: 801-819
Authors:  Zhao,Xia;  Li,Shuai;  Gaur,Uma;  Zheng,Wenhua
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3×Tg mice  Alzheimer's disease  Amyloid beta  Artemisinin  Cognitive behavior  SH-SY5Ycells  
ROS directly activates transforming growth factor β type 1 receptor signalling in human vascular smooth muscle cells Journal article
Biochimica et Biophysica Acta - General Subjects, 2020,Volume: 1864,Issue: 1
Authors:  Mohamed,Raafat;  Cao,Yingnan;  Afroz,Rizwana;  Xu,Suowen;  Ta,Hang T.;  Barras,Michael;  Zheng,Wenhua;  Little,Peter J.;  Kamato,Danielle
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Apocynin  NADPH oxidase  Reactive oxygen species  Smad2 carboxy terminal  Smooth muscle cells  Transforming growth factor β type 1 receptor  
Caffeic Acid Phenethyl Ester Protects against Experimental Autoimmune Encephalomyelitis by Regulating T Cell Activities Journal article
Oxidative Medicine and Cellular Longevity, 2020,Volume: 2020
Authors:  Zhou,Yifan;  Wang,Jingqi;  Chang,Yanyu;  Li,Rui;  Sun,Xiaobo;  Peng,Lisheng;  Zheng,Wenhua;  Qiu,Wei
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Foxo3a suppresses neuropeptide w expression in neuronal cells and in rat hypothalamus and its implication in hypothalamic-pituitary-adrenal (HPA) axis Journal article
International Journal of Biological Sciences, 2020,Volume: 16,Issue: 15,Page: 2775-2787
Authors:  Yan,Fengxia;  Wang,Rikang;  Li,Shuai;  Zhao,Xia;  Jiang,Yizhou;  Liu,Linlin;  Fang,Jiankang;  Zhen,Xuechu;  Lazarovici,Philip;  Zheng,Wenhua
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FoxO3a  Glucocorticoids  HPA axis dysfunction  Hypothalamus  Neuropeptide W (NPW)