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Diethyl blechnic, a novel natural product isolated from salvia miltiorrhiza bunge, inhibits doxorubicin-induced apoptosis by inhibiting ROS and activating JNK1/2 Journal article
International Journal of Molecular Sciences, 2018,Volume: 19,Issue: 6
Authors:  Yu J.;  Gao H.;  Wu C.;  Xu Q.-M.;  Lu J.-J.;  Chen X.
Favorite |  | TC[WOS]:10 TC[Scopus]:12 | Submit date:2018/12/28
Cardiotoxicity  Diethyl Blechnic  Dox  Jnk1/2  Ros  
Nepetoidin B, a Natural Product, Inhibits LPS-stimulated Nitric Oxide Production via Modulation of iNOS Mediated by NF-κB/MKP-5 Pathways Journal article
Phytotherapy Research, 2017,Volume: 31,Issue: 7,Page: 1072-1077
Authors:  Wu X.;  Gao H.;  Sun W.;  Yu J.;  Hu H.;  Xu Q.;  Chen X.
Favorite |  | TC[WOS]:8 TC[Scopus]:9 | Submit date:2018/12/28
Inducible Nitric Oxide Synthase, Nf-κb, Mkp-5  Nepetoidin b  Nitric Oxide  
A natural product-like JAK2/STAT3 inhibitor induces apoptosis of malignant melanoma cells Journal article
PLOS ONE, 2017,Volume: 12,Issue: 6
Authors:  Wu, Ke-Jia;  Huang, Jie-Min;  Zhong, Hai-Jing;  Dong, Zhen-Zhen;  Vellaisamy, Kasipandi;  Lu, Jin-Jian;  Chen, Xiu-Ping;  Chiu, Pauline;  Kwong, Daniel W. J.;  Han, Quan-Bin;  Ma, Dik-Lung;  Leung, Chung-Hang
Favorite |  | TC[WOS]:26 TC[Scopus]:27 | Submit date:2018/10/30
Dihydrotanshinone I attenuates atherosclerosis in ApoE-deficient mice: Role of NOX4/NF-κB mediated lectin-like oxidized LDL receptor-1 (LOX-1) of the Endothelium Journal article
Frontiers in Pharmacology, 2016,Volume: 7,Issue: NOV
Authors:  Zhao W.;  Li C.;  Gao H.;  Wu Q.;  Shi J.;  Chen X.
Favorite |  | TC[WOS]:30 TC[Scopus]:28 | Submit date:2018/12/28
Atherosclerosis  Dihydrotanshinone i  Lipopolysaccharide  Lox-1  Ros  
The Chemical Constituents and the Hepato-protective Effect of the Essential Oil of Ferulago campestris (Besser) Grecescu (Apiaceae) Journal article
Journal of Essential Oil-Bearing Plants, 2016,Volume: 19,Issue: 7,Page: 1701-1708
Authors:  Li W.;  Papa F.;  Shi J.;  Maggi F.;  Chen X.
Favorite |  | TC[WOS]:2 TC[Scopus]:4 | Submit date:2018/12/28
Cytokine  Essential Oil  Ferulago Campestris (Besser) Grecescu (Apiaceae)  Galactosamine/ Lipopolysaccharide  
Tanshinones and diethyl blechnics with anti-inflammatory and anti-cancer activities from Salvia miltiorrhiza Bunge (Danshen) Journal article
Scientific Reports, 2016,Volume: 6
Authors:  Gao H.;  Sun W.;  Zhao J.;  Wu X.;  Lu J.-J.;  Chen X.;  Xu Q.-M.;  Khan I.A.;  Yang S.
Favorite |  | TC[WOS]:41 TC[Scopus]:40 | Submit date:2018/12/28
Cryptotanshinone inhibits TNF-α-induced LOX-1 expression by suppressing reactive oxygen species (ROS) formation in endothelial cells Journal article
Korean Journal of Physiology and Pharmacology, 2016,Volume: 20,Issue: 4,Page: 347-355
Authors:  Ran X.;  Zhao W.;  Li W.;  Shi J.;  Chen X.
Favorite |  | TC[WOS]:14 TC[Scopus]:12 | Submit date:2018/12/28
Cryptotanshinone  Endothelial Cells  Lox-1  Ros  Tnf-α  
Isofuranodiene, the main volatile constituent of wild celery (Smyrnium olusatrum L.), protects d -galactosamin/lipopolysacchride-induced liver injury in rats Journal article
Natural Product Research, 2016,Volume: 30,Issue: 10,Page: 1162-1165
Authors:  Li W.;  Shi J.;  Papa F.;  Maggi F.;  Chen X.
Favorite |  | TC[WOS]:13 TC[Scopus]:13 | Submit date:2018/12/28
Galactosamine/lipopolysaccharide  Hepatoprotective  Isofuranodiene  Rats  
Ethanol enhances cucurbitacin B-induced apoptosis by inhibiting cucurbitacin B-induced autophagy in LO2 hepatocytes Journal article
Molecular and Cellular Toxicology, 2016,Volume: 12,Issue: 1,Page: 29-36
Authors:  Ding Q.;  Bao J.;  Zhao W.;  Lu J.;  Zhu H.;  Chen X.
Favorite |  | TC[WOS]:1 TC[Scopus]:1 | Submit date:2018/12/28
Apoptosis  Autophagy  Cucurbitacin b  Ethanol  Hepatocyte  
2-Methoxy-6-acetyl-7-methyljuglone (MAM), a natural naphthoquinone, induces NO-dependent apoptosis and necroptosis by H2O2-dependent JNK activation in cancer cells Journal article
Free Radical Biology and Medicine, 2016,Volume: 92,Page: 61-77
Authors:  Sun W.;  Bao J.;  Lin W.;  Gao H.;  Zhao W.;  Zhang Q.;  Leung C.-H.;  Ma D.-L.;  Lu J.;  Chen X.
Favorite |  | TC[WOS]:41 TC[Scopus]:44 | Submit date:2018/11/06
Apoptosis  Cancer  Mam  Necroptosis  No  Ros