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A 7-methoxybicoumarin derivative selectively inhibits BRD4 BD2 for anti-melanoma therapy Journal article
International Journal of Biological Macromolecules, 2020,Volume: 164,Page: 3204-3220
Authors:  Yang,Guan Jun;  Wang,Wanhe;  Lei,Pui Man;  Leung,Chung Hang;  Ma,Dik Lung
Favorite |  | TC[WOS]:0 TC[Scopus]:0 | Submit date:2021/03/01
BRD4  Bromodomain domain  Cell metastasis and invasion  Histone acetylation  Melanoma  Protein–protein interaction  Virtual screening  
Structure-guided discovery of a luminescent theranostic toolkit for living cancer cells and the imaging behavior effect Journal article
Chemical Science, 2020,Volume: 11,Issue: 42,Page: 11404-11412
Authors:  Wu,Chun;  Wu,Ke Jia;  Liu,Jin Biao;  Wang,Wanhe;  Leung,Chung Hang;  Ma,Dik Lung
Favorite |  | TC[WOS]:1 TC[Scopus]:1 | Submit date:2021/03/01
A long-lived luminogenic iridium(III) complex for acetylacetone detection in environmental samples Journal article
Sensors and Actuators, B: Chemical, 2020,Volume: 321
Authors:  Wang,Wanhe;  Yung,Tsan Ling;  Cheng,Sha Sha;  Chen,Feng;  Liu,Jin Biao;  Leung,Chung Hang;  Ma,Dik Lung
Favorite |  | TC[WOS]:0 TC[Scopus]:0 | Submit date:2021/03/01
Acetylacetone  Iridium(III) dimer  Luminogenic probe  Time-Resolved emission spectroscopy  
Peptide-Conjugated Long-Lived Theranostic Imaging for Targeting GRPr in Cancer and Immune Cells Journal article
Angewandte Chemie - International Edition, 2020,Volume: 59,Issue: 41,Page: 17897-17902
Authors:  Wang,Wanhe;  Wu,Ke Jia;  Vellaisamy,Kasipandi;  Leung,Chung Hang;  Ma,Dik Lung
Favorite |  | TC[WOS]:5 TC[Scopus]:6 | Submit date:2021/03/01
gastrin-releasing peptide receptor (GRPr)  peptide-conjugated transition-metal complexes  theranostic agents  time-resolved emission spectroscopy  
Interfering with S100B–effector protein interactions for cancer therapy Journal article
Drug Discovery Today, 2020,Volume: 25,Issue: 9,Page: 1754-1761
Authors:  Wu,Ke Jia;  Wang,Wanhe;  Wang,Hui Min David;  Leung,Chung Hang;  Ma,Dik Lung
Favorite |  | TC[WOS]:1 TC[Scopus]:1 | Submit date:2021/03/01
Recent Progress and Development of G-Quadruplex-Based Luminescent Assays for Ochratoxin A Detection Journal article
Frontiers in Chemistry, 2020,Volume: 8
Authors:  Nao,Sang Cuo;  Wu,Ke Jia;  Wang,Wanhe;  Leung,Chung Hang;  Ma,Dik Lung
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aptamer  food safety  G-quadruplex  nucleic acid detection  ochratoxin A  
The design and development of covalent protein-protein interaction inhibitors for cancer treatment Journal article
Journal of Hematology and Oncology, 2020,Volume: 13,Issue: 1
Authors:  Cheng,Sha Sha;  Yang,Guan Jun;  Wang,Wanhe;  Leung,Chung Hang;  Ma,Dik Lung
Favorite |  | TC[WOS]:7 TC[Scopus]:9 | Submit date:2021/03/01
Cancer therapy  Covalent inhibitors  Protein-protein interaction  
A long-lived peptide-conjugated iridium(iii) complex as a luminescent probe and inhibitor of the cell migration mediator, formyl peptide receptor 2 Journal article
CHEMICAL SCIENCE, 2018,Volume: 9,Issue: 43
Authors:  Vellaisamy, Kasipandi;  Li, Guodong;  Wang, Wanhe;  Leung, Chung-Hang;  Ma, Dik-Lung
Favorite |  | TC[WOS]:36 TC[Scopus]:36 | Submit date:2019/01/17
Selective Inhibition of Lysine-Specific Demethylase 5A (KDM5A) Using a Rhodium(III) Complex for Triple-Negative Breast Cancer Therapy Journal article
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2018,Volume: 57,Issue: 40,Page: 13091-13095
Authors:  Yang, Guan-Jun;  Wang, Wanhe;  Mok, Simon Wing Fai;  Wu, Chun;  Law, Betty Yuen Kwan;  Miao, Xiang-Min;  Wu, Ke-Jia;  Zhong, Hai-Jing;  Wong, Chun-Yuen;  Wong, Vincent Kam Wai;  Ma, Dik-Lung;  Leung, Chung-Hang
Favorite |  | TC[WOS]:47 TC[Scopus]:50 | Submit date:2018/10/30
Drug Discovery  Epigenetics  Medicinal Chemistry  Triple-negative Breast Cancer  
A dual-functional luminescent probe for imaging H2S in living zebrafish and discrimination hypoxic cells from normoxic cells Journal article
SENSORS AND ACTUATORS B-CHEMICAL, 2018,Volume: 255,Page: 1953-1959
Authors:  Wang, Wanhe;  Wu, Chun;  Yang, Chao;  Li, Guodong;  Han, Quan-Bin;  Li, Shengnan;  Lee, Simon Ming-Yuen;  Leung, Chung-Hang;  Ma, Dik-Lung
Favorite |  | TC[WOS]:19 TC[Scopus]:20 | Submit date:2018/10/30
Hydrogen Sulfide  Iridium(Iii) Complex  Sensor  Luminescence