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Natural alkaloid 8-oxo-epiberberine inhibited TGF-β1-triggred epithelial-mesenchymal transition by interfering Smad3 Journal article
Toxicology and Applied Pharmacology, 2020,Volume: 404
Authors:  Liu,Xin;  Zhang,Yiying;  ZHOU,Guang Ju;  Hou,Ying;  Kong,Qi;  Lu,Jin Jian;  Zhang,Qingwen;  Chen,Xiuping
Favorite |  | TC[WOS]:2 TC[Scopus]:3 | Submit date:2021/03/01
8-oxo-epiberberine  Epithelial-mesenchymal Transition  Metastasis  Tgf-β1  
Nagilactone D ameliorates experimental pulmonary fibrosis in vitro and in vivo via modulating TGF-β/Smad signaling pathway Journal article
Toxicology and Applied Pharmacology, 2020,Volume: 389
Authors:  Li,Ao;  Xiao,Xiao;  Feng,Zhe Ling;  Chen,Xiuping;  Liu,Li Juan;  Lin,Li Gen;  Lu,Jin Jian;  Zhang,Le Le
Favorite |  | TC[WOS]:5 TC[Scopus]:5 | Submit date:2021/03/01
Bleomycin  Fibrotic Process  Nagilactone d  Pulmonary Fibrosis  Tgf-β1  
HHQ-4, a quinoline derivate, preferentially inhibits proliferation of glucose-deprived breast cancer cells as a GRP78 down-regulator Journal article
Toxicology and Applied Pharmacology, 2019,Volume: 373,Page: 10-25
Authors:  Xiao,Xiao;  Li,Shuo;  Zhang,Xiaoxun;  Lu,Jinjian;  Wang,Weiguang;  Zhou,Shijia;  Zhang,Jingyao;  Wang,Rui;  Li,Ao
Favorite |  | TC[WOS]:3 TC[Scopus]:3 | Submit date:2021/03/02
Breast Cancer Cells  Glucose Deprivation  Glucose-regulated Protein 78  Hhq-4  Unfolded Protein Response  
γ-Mangostin alleviates liver fibrosis through Sirtuin 3-superoxide-high mobility group box 1 signaling axis Journal article
Toxicology and Applied Pharmacology, 2019,Volume: 363,Page: 142-153
Authors:  Wang A.;  Zhou F.;  Li D.;  Lu J.-J.;  Wang Y.;  Lin L.
Favorite |  | TC[WOS]:7 TC[Scopus]:6 | Submit date:2018/12/28
Fibrogenesis  Hmgb1  Liver Fibrosis  Sirtuin 3  Superoxide  Γ-mangostin  
Dihydronortanshinone, a natural product, alleviates LPS-induced inflammatory response through NF-κB, mitochondrial ROS, and MAPK pathways Journal article
Toxicology and Applied Pharmacology, 2018,Volume: 355,Page: 1-8
Authors:  Xiaxia Wu;  Hongwei Gao;  Ying Hou;  Jie Yu;  Wen Sun;  Ying Wang;  Xiaoyan Chen;  Yulin Feng;  Qiong-ming Xu;  Xiuping Chen
Favorite |  | TC[WOS]:22 TC[Scopus]:21 | Submit date:2018/12/28
Dihydronortanshinone  Inflammation  Lps  Macrophage  
Sodium tanshinone IIA sulfonate promotes endothelial integrity via regulating VE-cadherin dynamics and RhoA/ROCK-mediated cellular contractility and prevents atorvastatin-induced intracerebral hemorrhage in zebrafish Journal article
TOXICOLOGY AND APPLIED PHARMACOLOGY, 2018,Volume: 350,Page: 32-42
Authors:  Zhou, Zhong-Yan;  Huang, Bin;  Li, Shang;  Huang, Xiao-Hui;  Tang, Jing-Yi;  Kwan, Yiu Wa;  Hoi, Pui Man;  Lee, Simon Ming-Yuen
Favorite |  | TC[WOS]:15 TC[Scopus]:15 | Submit date:2018/10/30
Sodium Tanshinone Iia Sulfonate  Salvia Miltiorrhiza  Hemorrhagic Stroke  Atorvastatin  Rock  
Dihydrotanshinone I, a natural product, ameliorates DSS-induced experimental ulcerative colitis in mice Journal article
TOXICOLOGY AND APPLIED PHARMACOLOGY, 2018,Volume: 344,Page: 35-45
Authors:  Guo, Yanling;  Wu, Xiaxia;  Wu, Qin;  Lu, Yuanfu;  Shi, Jingshan;  Chen, Xiuping
Favorite |  | TC[WOS]:23 TC[Scopus]:21 | Submit date:2018/10/30
15,16-dihydrotanshinone i  Ulcerative Colitis  Inflammation  Necroptosis  
Pinocembrin from Penthorum chinense Pursh suppresses hepatic stellate cells activation through a unified SIRT3-TGF-beta-Smad signaling pathway Journal article
TOXICOLOGY AND APPLIED PHARMACOLOGY, 2018,Volume: 341,Page: 38-50
Authors:  Zhou, Fayang;  Wang, Anqi;  Li, Dan;  Wang, Yitao;  Lin, Ligen
View | Adobe PDF | Favorite |  | TC[WOS]:19 TC[Scopus]:19 | Submit date:2018/10/30
Liver Fibrosis  Hepatic Stellate Cells  Penthorum Chinense Pursh  Pinocembrin  Sma- And Mad-related Proteins  Silent Mating Type Information Regulation 2 Homolog 3  
Pinocembrin from Penthorum chinense Pursh suppresses hepatic stellate cells activation through a unified SIRT3-TGF-β-Smad signaling pathway Journal article
Toxicology and Applied Pharmacology, 2018,Volume: 341,Page: 38
Authors:  Fayang Zhou;  Anqi Wang;  Dan li;  Yitao Wang;  Ligen Lin
Favorite |  | TC[WOS]:19 TC[Scopus]:19 | Submit date:2018/10/31
Hepatic Stellate Cells  Liver Fibrosis  Penthorum Chinense Pursh  Pinocembrin  Silent Mating Type Information Regulation 2 Homolog 3  Sma- And Mad-related Proteins  
Novel Hsp90 inhibitor platycodin D disrupts Hsp90/Cdc37 complex and enhances the anticancer effect of mTOR inhibitor Journal article
TOXICOLOGY AND APPLIED PHARMACOLOGY, 2017,Volume: 330,Page: 65-73
Authors:  Li, Ting;  Chen, Xin;  Dai, Xiao-Yang;  Wei, Bin;  Weng, Qin-Jie;  Chen, Xiuping;  Ouyang, De-Fang;  Yan, Ru;  Huang, Zhang-Jian;  Jiang, Hu-Lin;  Zhu, Hong;  Lu, Jin-Jian
Favorite |  | TC[WOS]:21 TC[Scopus]:22 | Submit date:2018/10/30
Everolimus  Platycodin d  Hsp90  Cdc37  Egfr  Igf1r