UM

Browse/Search Results:  1-10 of 18 Help

Selected(0)Clear Items/Page:    Sort:
Characterization of BRCA1-deficient premalignant tissues and cancers identifies Plekha5 as a tumor metastasis suppressor Journal article
Nature Communications, 2020,Volume: 11,Issue: 1
Authors:  Liu,Jianlin;  Adhav,Ragini;  Miao,Kai;  Su,Sek Man;  Mo,Lihua;  Chan,Un In;  Zhang,Xin;  Xu,Jun;  Li,Jianjie;  Shu,Xiaodong;  Zeng,Jianming;  Zhang,Xu;  Lyu,Xueying;  Pardeshi,Lakhansing;  Tan,Kaeling;  Sun,Heng;  Wong,Koon Ho;  Deng,Chuxia;  Xu,Xiaoling
Favorite |  | TC[WOS]:1 TC[Scopus]:1 | Submit date:2021/03/02
Synthetic lethality of RB1 and aurora A is driven by stathmin-mediated disruption of microtubule dynamics Journal article
Nature Communications, 2020,Volume: 11,Issue: 1
Authors:  Lyu,Junfang;  Yang,Eun Ju;  Zhang,Baoyuan;  Wu,Changjie;  Pardeshi,Lakhansing;  Shi,Changxiang;  Mou,Pui Kei;  Liu,Yifan;  Tan,Kaeling;  Shim,Joong Sup
Favorite |  | TC[WOS]:1 TC[Scopus]:1 | Submit date:2021/03/04
NOTCH1 activation compensates BRCA1 deficiency and promotes triple-negative breast cancer formation Journal article
Nature Communications, 2020,Volume: 11,Issue: 1
Authors:  Miao,Kai;  Lei,Josh Haipeng;  Valecha,Monica Vishnu;  Zhang,Aiping;  Xu,Jun;  Wang,Lijian;  Lyu,Xueying;  Chen,Si;  Miao,Zhengqiang;  Zhang,Xin;  Su,Sek Man;  Shao,Fangyuan;  Rajendran,Barani Kumar;  Bao,Jiaolin;  Zeng,Jianming;  Sun,Heng;  Chen,Ping;  Tan,Kaeling;  Chen,Qiang;  Wong,Koon Ho;  Xu,Xiaoling;  Deng,Chu Xia
Favorite |  | TC[WOS]:3 TC[Scopus]:1 | Submit date:2020/09/16
A Three-Way Combinatorial CRISPR Screen for Analyzing Interactions among Druggable Targets Journal article
Cell Reports, 2020,Volume: 32,Issue: 6
Authors:  Zhou,Peng;  Chan,Becky K.C.;  Wan,Yuk Kei;  Yuen,Chaya T.L.;  Choi,Gigi C.G.;  Li,Xinran;  Tong,Cindy S.W.;  Zhong,Sophia S.W.;  Sun,Jieran;  Bao,Yufan;  Mak,Silvia Y.L.;  Chow,Maggie Z.Y.;  Khaw,Jien Vei;  Leung,Suet Yi;  Zheng,Zongli;  Cheung,Lydia W.T.;  Tan,Kaeling;  Wong,Koon Ho;  Chan,H. Y.Edwin;  Wong,Alan S.L.
Favorite |  | TC[WOS]:0 TC[Scopus]:0 | Submit date:2021/03/04
Cancer  Combigem  Combination Therapy  Combinatorial Genetics  Crispr  Drug Interaction  Genetic Interaction  High-throughput Screening  Neurodegeneration  Parkinson's Disease  
The Aspergillus fumigatus transcription factor RglT is important for gliotoxin biosynthesis and self-protection, and virulence Journal article
PLoS Pathogens, 2020,Volume: 16,Issue: 7
Authors:  Ries,Laure N.A.;  Pardeshi,Lakhansing;  Dong,Zhiqiang;  Tan,Kaeling;  Steenwyk,Jacob L.;  Colabardini,Ana Cristina;  Filho,Jaire A.Ferreira;  De Castro,Patricia A.;  Silva,Lilian P.;  Preite,Nycolas W.;  Almeida,Fausto;  De Assis,Leandro J.;  Dos Santos,Renato A.C.;  Bowyer,Paul;  Bromley,Michael;  Owens,Rebecca A.;  Doyle,Sean;  Demasi,Marilene;  Hernández,Diego C.R.;  Netto,Luís Eduardo S.;  Pupo,Monica T.;  Rokas,Antonis;  Loures,Flavio V.;  Wong,Koon H.;  Goldman,Gustavo H.
Favorite |  | TC[WOS]:2 TC[Scopus]:2 | Submit date:2021/03/04
Transcriptomic analysis reveals global and temporal transcription changes during Candida glabrata adaptation to an oxidative environment Journal article
Fungal Biology, 2020,Volume: 124,Issue: 5,Page: 427-439
Authors:  Sethiya,Pooja;  Rai,Maruti Nandan;  Rai,Rikky;  Parsania,Chirag;  Tan,Kaeling;  Wong,Koon Ho
Favorite |  | TC[WOS]:3 TC[Scopus]:3 | Submit date:2021/03/04
Oxidative Stress  Pathogenic Fungi  Transcriptome Profiling  
Class I histone deacetylase inhibition is synthetic lethal with BRCA1 deficiency in breast cancer cells Journal article
Acta Pharmaceutica Sinica B, 2020,Volume: 10,Issue: 4,Page: 615-627
Authors:  Zhang,Baoyuan;  Lyu,Junfang;  Yang,Eun Ju;  Liu,Yifan;  Wu,Changjie;  Pardeshi,Lakhansing;  Tan,Kaeling;  Chen,Qiang;  Xu,Xiaoling;  Deng,Chu Xia;  Shim,Joong Sup
Favorite |  | TC[WOS]:4 TC[Scopus]:7 | Submit date:2020/09/16
Brca1  Breast Cancer  Dna Damage  Hdac  Histone Deacetylase  Reactive Oxygen Species  Synthetic Lethality  
Combinatorial mutagenesis en masse optimizes the genome editing activities of SpCas9 Journal article
NATURE METHODS, 2019,Volume: 16,Issue: 8,Page: 722–730
Authors:  Gigi C. G. Choi;  Peng Zhou;  Chaya T. L. Yuen;  Becky K. C. Chan;  Feng Xu;  Siyu Bao;  Hoi Yee Chu;  Dawn Thean;  Kaeling Tan;  Koon Ho Wong;  Zongli Zheng;  Alan S. L. Wong
Favorite |  | TC[WOS]:11 TC[Scopus]:13 | Submit date:2020/05/21
Universal plasmids to facilitate gene deletion and gene tagging in filamentous fungi Journal article
FUNGAL GENETICS AND BIOLOGY, 2019,Volume: 125,Page: 28-35
Authors:  Longguang Qin;  Ang Li;  Kaeling Tan;  Shuhui Guo;  Yingying Chen;  Fang Wang;  Koon Ho Wong
Favorite |  | TC[WOS]:0 TC[Scopus]:0 | Submit date:2020/05/21
Gene Deletion  Epitope Tagging  Selectable Markers  Plasmid Collection  Filamentous Fungi  Aspergillus  
BRCA1 deficiency sensitizes breast cancer cells to bromodomain and extra-terminal domain (BET) inhibition Journal article
Oncogene, 2018,Issue: 37,Page: 6341–6356
Authors:  Baoyuan Zhang;  Junfang Lyu;  Yifan Liu;  Changjie Wu;  Eun Ju Yang;  Lakhansing Pardeshi;  Kaeling Tan;  Koon Ho Wong;  Qiang Chen;  Xiaoling Xu;  Chu-Xia Deng;  Joong Sup Shim
Favorite |  | TC[WOS]:6 TC[Scopus]:6 | Submit date:2018/12/17