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Synthesis, biological evaluation and structure-activity relationship of novel dichloroacetophenones targeting pyruvate dehydrogenase kinases with potent anticancer activity Journal article
European Journal of Medicinal Chemistry, 2021,Volume: 214
Authors:  Xu,Biao;  Wang,Zhi Peng;  Liu,Qingwang;  Yang,Xiaohong;  Li,Xuemin;  Huang,Ding;  Qiu,Yanfei;  Tam,Kin Yip;  Zhang,Shao Lin;  He,Yun
Favorite |  | TC[WOS]:0 TC[Scopus]:0 | Submit date:2021/03/04
Cancer metabolism  Proliferation  Pyruvate dehydrogenase kinase  Structure-activity relationship  
Recent developments of human monocarboxylate transporter (hMCT) inhibitors as anticancer agents Journal article
Drug Discovery Today, 2021
Authors:  Wu,Puhua;  Zhou,Yan;  Guo,Yizhen;  Zhang,Shao Lin;  Tam,Kin Yip
Favorite |  | TC[WOS]:0 TC[Scopus]:0 | Submit date:2021/03/04
Two-dimensional Ruddlesden–Popper layered perovskite solar cells based on phase-pure thin films Journal article
Nature Energy, 2021,Volume: 6,Issue: 1,Page: 38-45
Authors:  Liang,Chao;  Gu,Hao;  Xia,Yingdong;  Wang,Zhuo;  Liu,Xiaotao;  Xia,Junmin;  Zuo,Shouwei;  Hu,Yue;  Gao,Xingyu;  Hui,Wei;  Chao,Lingfeng;  Niu,Tingting;  Fang,Min;  Lu,Hui;  Dong,Han;  Yu,Hui;  Chen,Shi;  Ran,Xueqin;  Song,Lin;  Li,Bixin;  Zhang,Jing;  Peng,Yong;  Shao,Guosheng;  Wang,Jianpu;  Chen,Yonghua;  Xing,Guichuan;  Huang,Wei
Favorite |  | TC[WOS]:32 TC[Scopus]:26 | Submit date:2021/03/11
Few-layer MoS2 embedded in N-doped carbon fibers with interconnected macropores for ultrafast sodium storage Journal article
Carbon, 2020,Volume: 168,Page: 691-700
Authors:  Cheng,Ao;  Zhang,Haiyan;  Zhong,Weihao;  Li,Zhaopeng;  Cheng,Dejian;  Lin,Yingxi;  Tang,Yudie;  Shao,Huaiyu;  Li,Zhenghui
Favorite |  | TC[WOS]:7 TC[Scopus]:7 | Submit date:2021/03/11
Development of dual inhibitors targeting pyruvate dehydrogenase kinases and human lactate dehydrogenase A: High-throughput virtual screening, synthesis and biological validation Journal article
European Journal of Medicinal Chemistry, 2020,Volume: 203
Authors:  Xiang,Sichuan;  Huang,Ding;  He,Qiaolin;  Li,Jie;  Tam,Kin Yip;  Zhang,Shao Lin;  He,Yun
Favorite |  | TC[WOS]:2 TC[Scopus]:2 | Submit date:2021/03/04
Cancer metabolism  Cancer proliferation  Dual inhibitor  Lactate dehydrogenase A  Pyruvate dehydrogenase kinase  
Defining the composition and electronic structure of large-scale and single-crystalline like Cs 2 AgBiBr 6 films fabricated by capillary-assisted dip-coating method Journal article
Materials Today Energy, 2019,Volume: 12,Page: 186-197
Authors:  Jingwei Xiu;  Yangfan Shao;  Linxun Chen;  Yue Feng;  Junfeng Dai;  Xusheng Zhang;  Yi Lin;  Yudong Zhu;  Zhenggang Wu;  Yini Zheng;  Hui Pan;  Chang Liu;  Xingqiang Shi;  Xin Cheng;  Zhubing He
Favorite |  | TC[WOS]:12 TC[Scopus]:11 | Submit date:2019/04/08
Single-crystalline Perovskite Films  
Novel Molecular Doping Mechanism for n-Doping of SnO 2 via Triphenylphosphine Oxide and Its Effect on Perovskite Solar Cells Journal article
Advanced Materials, 2019
Authors:  Tu B.;  Shao Y.;  Chen W.;  Wu Y.;  Li X.;  He Y.;  Li J.;  Liu F.;  Zhang Z.;  Lin Y.;  Lan X.;  Xu L.;  Shi X.;  Ng A.M.C.;  Li H.;  Chung L.W.;  Djurisic A.B.;  He Z.
Favorite |  | TC[WOS]:58 TC[Scopus]:56 | Submit date:2019/04/08
delocalized electrons  molecular doping  n-type  perovskite solar cells  SnO 2  
Dichloroacetophenones targeting at pyruvate dehydrogenase kinase 1 with improved selectivity and antiproliferative activity: Synthesis and structure-activity relationships Journal article
Bioorganic and Medicinal Chemistry Letters, 2018,Volume: 28,Issue: 21,Page: 3441-3445
Authors:  Zhang,Shao Lin;  Yang,Zheng;  Hu,Xiaohui;  Tam,Kin Yip
Favorite |  | TC[WOS]:4 TC[Scopus]:5 | Submit date:2021/03/04
Antiproliferative activity  Dichloroacetophenone  Kinase inhibition  Pyruvate dehydrogenase complex  Pyruvate dehydrogenase kinase  
Dichloroacetophenones targeting at pyruvate dehydrogenase kinase 1 with improved selectivity and antiproliferative activity: Synthesis and structure-activity relationships Journal article
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2018,Volume: 28,Issue: 21,Page: 3441-3445
Authors:  Zhang, Shao-Lin;  Yang, Zheng;  Hu, Xiaohui;  Tam, Kin Yip
Favorite |  | TC[WOS]:4 TC[Scopus]:5 | Submit date:2018/10/30
Pyruvate dehydrogenase kinase  Pyruvate dehydrogenase complex  Antiproliferative activity  Dichloroacetophenone  Kinase inhibition  
Inhibition of pyruvate dehydrogenase kinase 1 enhances the anti-cancer effect of EGFR tyrosine kinase inhibitors in non-small cell lung cancer Journal article
EUROPEAN JOURNAL OF PHARMACOLOGY, 2018,Volume: 838,Page: 41-52
Authors:  Yang, Zheng;  Zhang, Shao-Lin;  Hu, Xiaohui;  Tam, Kin Yip
Favorite |  | TC[WOS]:10 TC[Scopus]:10 | Submit date:2018/10/30
Dichloroacetophenone  Epidermal Growth Factor Receptor  Tyrosine Kinase Inhibitor  Synergism  Hypoxia  Oxidative Phosphorylation