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Time-resolved luminescent high-throughput screening platform for lysosomotropic compounds in living cells Journal article
ACS Sensors, 2021
Authors:  Wu,Ke Jia;  Wu,Chun;  Chen,Feng;  Cheng,Sha Sha;  Ma,Dik Lung;  Leung,Chung Hang
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High-throughput screening  Iridium-based pH probe  Lysosomotropic compounds  Mitoxantrone  Time-resolved emission spectroscopy  
Brain-targeted delivery shuttled by black phosphorus nanostructure to treat Parkinson's disease Journal article
Biomaterials, 2020,Volume: 260
Authors:  Xiong,Sha;  Li,Zhongjun;  Liu,Yao;  Wang,Qun;  Luo,Jingshan;  Chen,Xiaojia;  Xie,Zhongjian;  Zhang,Yuan;  Zhang,Han;  Chen,Tongkai
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Black Phosphorus Nanosheets  Blood-brain Barrier  Brain Targeting  Drug Delivery  Lactoferrin  
A long-lived luminogenic iridium(III) complex for acetylacetone detection in environmental samples Journal article
Sensors and Actuators, B: Chemical, 2020,Volume: 321
Authors:  Wang,Wanhe;  Yung,Tsan Ling;  Cheng,Sha Sha;  Chen,Feng;  Liu,Jin Biao;  Leung,Chung Hang;  Ma,Dik Lung
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Acetylacetone  Iridium(III) dimer  Luminogenic probe  Time-Resolved emission spectroscopy  
Black phosphorus as a versatile nanoplatform: From unique properties to biomedical applications Journal article
Journal of Innovative Optical Health Sciences, 2020,Volume: 13,Issue: 5
Authors:  Xiong,Sha;  Chen,Xiaojia;  Liu,Yao;  Fan,Taojian;  Wang,Qi;  Zhang,Han;  Chen,Tongkai
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Bioimaging  Biosensing  Black Phosphorus  Cancer Therapy  Drug Delivery  
Enhancement of oral bioavailability and anti-Parkinsonian efficacy of resveratrol through a nanocrystal formulation Journal article
Asian Journal of Pharmaceutical Sciences, 2020,Volume: 15,Issue: 4,Page: 518-528
Authors:  Xiong,Sha;  Liu,Wei;  Zhou,Yile;  Mo,Yousheng;  Liu,Yao;  Chen,Xiaojia;  Pan,Huafeng;  Yuan,Dongsheng;  Wang,Qi;  Chen,Tongkai
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Anti-parkinsonian Efficacy  Brain Permeability  Nanocrystals  Oral Absorption  Resveratrol  
Exosomes derived from normal human bronchial epithelial cells down-regulate proliferation and migration of hydroquinone-transformed malignant recipient cells via up-regulating PTEN expression Journal article
Chemosphere, 2020,Volume: 244
Authors:  Lian,Zhenwei;  Hu,Zuqing;  Xian,Hongyi;  Jiang,Ran;  Huang,Haoyu;  Jiang,Yunxia;  Zheng,Zhongdaixi;  Lloyd,R. Stephen;  Yuan,Jianhui;  Sha,Yan;  Wang,Sanming;  Hu,Dalin
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Benzene  Exosomes  Migration  Proliferation  PTEN  Toxicity  
The design and development of covalent protein-protein interaction inhibitors for cancer treatment Journal article
Journal of Hematology and Oncology, 2020,Volume: 13,Issue: 1
Authors:  Cheng,Sha Sha;  Yang,Guan Jun;  Wang,Wanhe;  Leung,Chung Hang;  Ma,Dik Lung
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Cancer therapy  Covalent inhibitors  Protein-protein interaction  
Highly stabilized nanocrystals delivering Ginkgolide B in protecting against the Parkinson's disease Journal article
International Journal of Pharmaceutics, 2020,Volume: 577
Authors:  Liu,Yao;  Liu,Wei;  Xiong,Sha;  Luo,Jingshan;  Li,Ye;  Zhao,Yuying;  Wang,Qun;  Zhang,Zexin;  Chen,Xiaojia;  Chen,Tongkai
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Blood-brain Barrier  Drug Delivery  Gastrointestinal Tract  Nanocrystals  Parkinson's Disease  
Exosomal miR-221 derived from hydroquinone-transformed malignant human bronchial epithelial cells is involved in cell viability of recipient cells Journal article
Journal of Applied Toxicology, 2020,Volume: 40,Issue: 2,Page: 224-233
Authors:  Jiang,Ran;  Huang,Haoyu;  Lian,Zhenwei;  Hu,Zuqing;  Lloyd,R. Stephen;  Fang,Daokui;  Li,Yanfeng;  Xian,Hongyi;  Yuan,Jianhui;  Sha,Yan;  Wang,Sanming;  Hu,Dalin
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benzene  cell viability  exosomes  intercellular communications  miR-221  toxic mechanism  
NRBF2 is a RAB7 effector required for autophagosome maturation and mediates the association of APP-CTFs with active form of RAB7 for degradation Journal article
Autophagy, 2020
Authors:  Cai,Cui Zan;  Yang,Chuanbin;  Zhuang,Xu Xu;  Yuan,Ning Ning;  Wu,Ming Yue;  Tan,Jie Qiong;  Song,Ju Xian;  Cheung,King Ho;  Su,Huanxing;  Wang,Yi Tao;  Tang,Bei Sha;  Behrends,Christian;  Durairajan,Siva Sundara Kumar;  Yue,Zhenyu;  Li,Min;  Lu,Jia Hong
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Amaturation  Autophagy  CCZ1-MON1A  NRBF2  PI3KC3/VPS34  RAB7  trafficking