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A 7-methoxybicoumarin derivative selectively inhibits BRD4 BD2 for anti-melanoma therapy Journal article
International Journal of Biological Macromolecules, 2020,Volume: 164,Page: 3204-3220
Authors:  Yang,Guan Jun;  Wang,Wanhe;  Lei,Pui Man;  Leung,Chung Hang;  Ma,Dik Lung
Favorite |  | TC[WOS]:0 TC[Scopus]:0 | Submit date:2021/03/01
BRD4  Bromodomain domain  Cell metastasis and invasion  Histone acetylation  Melanoma  Protein–protein interaction  Virtual screening  
The design and development of covalent protein-protein interaction inhibitors for cancer treatment Journal article
Journal of Hematology and Oncology, 2020,Volume: 13,Issue: 1
Authors:  Cheng,Sha Sha;  Yang,Guan Jun;  Wang,Wanhe;  Leung,Chung Hang;  Ma,Dik Lung
Favorite |  | TC[WOS]:9 TC[Scopus]:10 | Submit date:2021/03/01
Cancer therapy  Covalent inhibitors  Protein-protein interaction  
Engineered delivery strategies for enhanced control of growth factor activities in wound healing Journal article
Advanced Drug Delivery Reviews, 2019,Volume: 146,Page: 190-208
Authors:  Niu,Yiming;  Li,Qiu;  Ding,Ya;  Dong,Lei;  Wang,Chunming
Favorite |  | TC[WOS]:28 TC[Scopus]:31 | Submit date:2021/03/02
Biomaterials scaffolds  Controlled delivery system  Extracellular matrix  Glycosaminoglycan-protein interaction  Molecular engineering  Skin tissue regeneration  Therapeutic angiogenesis  
Structure-Based Discovery of a Selective KDM5A Inhibitor that Exhibits Anti-Cancer Activity via Inducing Cell Cycle Arrest and Senescence in Breast Cancer Cell Lines Journal article
CANCERS, 2019,Volume: 11,Issue: 1
Authors:  Yang, GJ;  Ko, CN;  Zhong, HJ;  Leung, CH;  Ma, DL
Favorite |  | TC[WOS]:13 TC[Scopus]:10 | Submit date:2020/03/24
Cell Cycle Arrest  Kdm5a  Jumonji Domain  Histone Demethylation  Protein-protein Interaction  Virtual Screening  Breast Cancer  Cell Senescence  
Emerging Screening Approaches in the Development of Nrf2-Keap1 Protein-Protein Interaction Inhibitors Journal article
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2019,Volume: 20,Issue: 18
Authors:  Leung, CH;  Zhang, JT;  Yang, GJ;  Liu, H;  Han, QB;  Ma, DL
Favorite |  | TC[WOS]:15 TC[Scopus]:14 | Submit date:2020/03/23
Virtual Screening  Keap1-nrf2  Protein-protein Interaction  Inhibitors  Oxidative Stress  
Engineered delivery strategies for enhanced control of growth factor activities in wound healing Journal article
Advanced Drug Delivery Reviews, 2018
Authors:  Yiming Niu;  Qiu Li;  Ya Ding;  Lei Dong;  Chunming Wang
Favorite |  | TC[WOS]:0 TC[Scopus]:31 | Submit date:2018/11/30
Biomaterials Scaffolds  Controlled Delivery System  Skin Tissue Regeneration  Molecular Engineering  Extracellular Matrix  Glycosaminoglycan-protein Interaction  Therapeutic Angiogenesis  
Targeting the Hsp90-Cdc37-client protein interaction to disrupt Hsp90 chaperone machinery Journal article
JOURNAL OF HEMATOLOGY & ONCOLOGY, 2018,Volume: 11
Authors:  Li, Ting;  Jiang, Hu-Lin;  Tong, Yun-Guang;  Lu, Jin-Jian
Favorite |  | TC[WOS]:20 TC[Scopus]:21 | Submit date:2018/10/30
Hsp90 Chaperone Machinery  Cdc37  Kinase Client  Protein Interaction  
Granulin-epithelin precursor interacts with 78-kDa glucose-regulated protein in hepatocellular carcinoma Journal article
BMC CANCER, 2017,Volume: 17
Authors:  Chi Wai Yip;  Ching Yan Lam;  Terence C. W. Poon;  Tan To Cheung;  Phyllis F. Y. Cheung;  Sze Wai Fung;  Xiao Qi Wang;  Idy C. Y. Leung;  Linda W. C. Ng;  Chung Mau Lo;  George S. W. Tsao;  Siu Tim Cheung
Favorite |  | TC[WOS]:5 TC[Scopus]:6 | Submit date:2018/10/30
Granulin-epithelin Precursor  78-kda Glucose-regulated Protein  Hepatocellular Carcinoma  Mass Spectrometry  Protein Interaction  
An analysis of evolutionary conservation based on genomic orthology and protein-protein interaction networks Book chapter
出自: Biotechnology in Hong Kong Volume III, Whitestone, New York:United State-China Itelletual Property Institute Inc, 2017, 页码: 49-60
Authors:  Hui Hens Lin;  Pengpeng Li;  Xiangjun Kong;  Jing Cai;  Shibing Su;  Yuanjia Hu;  Hui Hens Lin;  Pengpeng Li;  Xiangjun Kong;  Jing Cai;  Shibing Su;  Yuanjia Hu
Favorite |  | TC[WOS]:0 TC[Scopus]:0 | Submit date:2019/01/14
Protein-protein Interaction Networks  Evolutionary Conservation  Orthologs  
Inhibition of the p53/hDM2 protein-protein interaction by cyclometallated iridium(III) compounds Journal article
Oncotarget, 2016,Volume: 7,Issue: 12,Page: 13965
Authors:  Liu L.-J.;  He B.;  Miles J.A.;  Wang W.;  Mao Z.;  Che W.I.;  Lu J.-J.;  Chen X.-P.;  Wilson A.J.;  Ma D.-L.;  Leung C.-H.
Favorite |  | TC[WOS]:20 TC[Scopus]:20 | Submit date:2018/10/30
Hdm2  Metal-based Inhibitor  P53  Protein-protein Interaction