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Structure-based identification of a NEDD8-activating enzyme inhibitor via drug repurposing Journal article
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2018,Volume: 143,Page: 1021-1027
Authors:  Wu, Ke-Jia;  Zhong, Hai-Jing;  Li, Guodong;  Liu, Chenfu;  Wang, Hui-Min David;  Ma, Dik-Lung;  Leung, Chung-Hang
Favorite |  | TC[WOS]:34 TC[Scopus]:35 | Submit date:2018/10/30
Drug Repurposing  Mitoxantrone  Nedd8  Ubiquitin  
Nedd8 modification of Cullin-5 regulates lipopolysaccharide-induced acute lung injury Journal article
AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY, 2017,Volume: 313,Issue: 1,Page: L104-L114
Authors:  Zhu, Ziyan;  Sun, Lei;  Hao, Rui;  Jiang, Hongchao;  Qian, Feng;  Ye, Richard D.
Favorite |  | TC[WOS]:13 TC[Scopus]:14 | Submit date:2018/10/30
Cullin-5  macrophage  Nedd8  acute lung injury  
Discovery of deoxyvasicinone derivatives as inhibitors of NEDD8-activating enzyme Journal article
Methods, 2015,Volume: 71,Issue: C,Page: 71-76
Authors:  Zhong H.-J.;  Leung K.-H.;  Lin S.;  Chan D.S.-H.;  Han Q.-B.;  Chan S.L.-F.;  Ma D.-L.;  Leung C.-H.
Favorite |  | TC[WOS]:11 TC[Scopus]:10 | Submit date:2018/11/06
Deoxyvasicinone  Drug Discovery  Nedd8  Pharmacophore  Ubiquitin-like