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In Vivo Screening of Xanthones from Garcinia oligantha Identified Oliganthin H as a Novel Natural Inhibitor of Convulsions Journal article
Journal of Natural Products, 2020,Volume: 83,Issue: 12,Page: 3706-3716
Authors:  Gong,Guiyi;  Chen,Hanbin;  Kam,Hiotong;  Chan,Ging;  Tang,Yue Xun;  Wu,Man;  Tan,Hongsheng;  Tse,Yu Chung;  Xu,Hong Xi;  Lee,Simon Ming Yuen
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Deciphering the microbial taxonomy and functionality of two diverse mangrove ecosystems and their potential abilities to produce bioactive compounds Journal article
mSystems, 2020,Volume: 5,Issue: 5
Authors:  Liao,Shuilin;  Wang,Yayu;  Liu,Huan;  Fan,Guangyi;  Sahu,Sunil Kumar;  Jin,Tao;  Chen,Jianwei;  Zhang,Pengfan;  Gram,Lone;  Strube,Mikael Lenz;  Shi,Qiong;  Lee,Simon Ming Yuen;  Liu,Xin
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Antibiotic resistance genes  Biosynthesis gene clusters  Mangroves  Metagenomics  Rhizosphere  
An Indo-Pacific Humpback Dolphin Genome Reveals Insights into Chromosome Evolution and the Demography of a Vulnerable Species Journal article
iScience, 2020,Volume: 23,Issue: 10
Authors:  Zhang,Peijun;  Zhao,Yong;  Li,Chang;  Lin,Mingli;  Dong,Lijun;  Zhang,Rui;  Liu,Mingzhong;  Li,Kuan;  Zhang,He;  Liu,Xiaochuan;  Zhang,Yaolei;  Yuan,Yuan;  Liu,Huan;  Seim,Inge;  Sun,Shuai;  Du,Xiao;  Chang,Yue;  Li,Feida;  Liu,Shanshan;  Lee,Simon Ming Yuen;  Wang,Kun;  Wang,Ding;  Wang,Xianyan;  McGowen,Michael R.;  Jefferson,Thomas A.;  Olsen,Morten Tange;  Stiller,Josefin;  Zhang,Guojie;  Xu,Xun;  Yang,Huanming;  Fan,Guangyi;  Liu,Xin;  Li,Songhai
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Evolutionary Biology  Genetics  Genomics  
Neuroprotective Potency of Saffron Against Neuropsychiatric Diseases, Neurodegenerative Diseases, and Other Brain Disorders: From Bench to Bedside Journal article
Frontiers in Pharmacology, 2020,Volume: 11
Authors:  Bian,Yaqi;  Zhao,Chen;  Lee,Simon Ming Yuen
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anti-depressant effect  anxiolytic effect  neuroprotective effects  saffron  saffron constituents  traditional Chinese medicine  
Mechanism Study of the Protective Effects of Sodium Tanshinone IIA Sulfonate Against Atorvastatin-Induced Cerebral Hemorrhage in Zebrafish: Transcriptome Analysis Journal article
Frontiers in Pharmacology, 2020,Volume: 11
Authors:  Zhou,Zhong Yan;  Zhao,Wai Rong;  Xiao,Ying;  Zhang,Jing;  Tang,Jing Yi;  Lee,Simon Ming Yuen
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atorvastatin  carbonic anhydrase  cerebral hemorrhage  hemoglobin  hypoxia-inducible factor 1  Na+/H+ exchanger  sodium tanshinone IIA sulfonate  traditional Chinese medicine  
Toward understanding the prolonged circulation and elimination mechanism of crosslinked polymeric micelles in zebrafish model Journal article
Biomaterials, 2020,Volume: 256
Authors:  Tao,Jinsong;  Wei,Zhengjie;  He,Yuan;  Yan,Xingyang;  Ming-Yuen Lee,Simon;  Wang,Xueqing;  Ge,Wei;  Zheng,Ying
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Crosslinked polymeric micelles  Elimination mechanism  FRET  In vivo integrity  Scavenger receptors  Zebrafish larvae model  
Dynamics of bacteriophages in gut of giant pandas reveal a potential regulation of dietary intake on bacteriophage composition Journal article
Science of the Total Environment, 2020,Volume: 734
Authors:  Guo,Min;  Liu,Guilin;  Chen,Jianwei;  Ma,Jinmin;  Lin,Jinzhong;  Fu,Ying;  Fan,Guangyi;  Lee,Simon Ming Yuen;  Zhang,Libiao
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Diet-related bacteriophages  Dietary intake  Dynamics between bacteriophages and bacteria  Giant panda  Gut bacteriophages  
Exploring the Potential of Antibiotic Production From Rare Actinobacteria by Whole-Genome Sequencing and Guided MS/MS Analysis Journal article
Frontiers in Microbiology, 2020,Volume: 11
Authors:  Hu,Dini;  Sun,Chenghang;  Jin,Tao;  Fan,Guangyi;  Mok,Kai Meng;  Li,Kai;  Lee,Simon Ming Yuen
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antibiotics  mangroves  mass spectrometry  rare actinobacteria  whole-genome sequencing  
Oxyphylla a promotes degradation of α-synuclein for neuroprotection via activation of immunoproteasome Journal article
Aging and Disease, 2020,Volume: 11,Issue: 3,Page: 559-574
Authors:  Zhou,Hefeng;  Li,Shengnan;  Li,Chuwen;  Yang,Xuanjun;  Li,Haitao;  Zhong,Hanbing;  Lu,Jia Hong;  Lee,Simon Ming Yuen
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Degradation  Neuroprotection  Parkinson's disease  Proteasome  α-synuclein  
Dietary compound glycyrrhetinic acid suppresses tumor angiogenesis and growth by modulating antiangiogenic and proapoptotic pathways in vitro and in vivo Journal article
Journal of Nutritional Biochemistry, 2020,Volume: 77
Authors:  Li,Jingjing;  Tang,Fan;  Li,Renkai;  Chen,Zhejie;  Lee,Simon Ming Yuen;  Fu,Chaomei;  Zhang,Jinming;  Leung,George Pak Heng
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Antiangiogenesis  Apoptosis  Dietary compound  Glycyrrhetinic acid  Ovarian cancer