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Synthesis, biological evaluation and structure-activity relationship of novel dichloroacetophenones targeting pyruvate dehydrogenase kinases with potent anticancer activity Journal article
European Journal of Medicinal Chemistry, 2021,Volume: 214
Authors:  Xu,Biao;  Wang,Zhi Peng;  Liu,Qingwang;  Yang,Xiaohong;  Li,Xuemin;  Huang,Ding;  Qiu,Yanfei;  Tam,Kin Yip;  Zhang,Shao Lin;  He,Yun
Favorite |  | TC[WOS]:0 TC[Scopus]:0 | Submit date:2021/03/04
Cancer metabolism  Proliferation  Pyruvate dehydrogenase kinase  Structure-activity relationship  
Development of dual inhibitors targeting pyruvate dehydrogenase kinases and human lactate dehydrogenase A: High-throughput virtual screening, synthesis and biological validation Journal article
European Journal of Medicinal Chemistry, 2020,Volume: 203
Authors:  Xiang,Sichuan;  Huang,Ding;  He,Qiaolin;  Li,Jie;  Tam,Kin Yip;  Zhang,Shao Lin;  He,Yun
Favorite |  | TC[WOS]:2 TC[Scopus]:2 | Submit date:2021/03/04
Cancer metabolism  Cancer proliferation  Dual inhibitor  Lactate dehydrogenase A  Pyruvate dehydrogenase kinase  
Role of FOXO Transcription Factors in Cancer Metabolism and Angiogenesis Journal article
Cells, 2020,Volume: 9,Issue: 7
Authors:  Farhan,Mohd;  Silva,Marta;  Xingan,Xing;  Huang,Yu;  Zheng,Wenhua
Favorite |  | TC[WOS]:4 TC[Scopus]:4 | Submit date:2021/03/04
angiogenesis  cancer  cancer metabolism  FOXOs  
SIRT3 acts as a positive autophagy regulator to promote lipid mobilization in adipocytes via activating AMPK Journal article
International Journal of Molecular Sciences, 2020,Volume: 21,Issue: 2
Authors:  Zhang,Tian;  Liu,Jingxin;  Tong,Qiang;  Lin,Ligen
Favorite |  | TC[WOS]:6 TC[Scopus]:4 | Submit date:2021/03/01
AMPK  Chaperone-mediated autophagy  Lipid metabolism  Macroautophagy  Sirtuin 3  
Generation of Human Fatty Livers Using Custom-Engineered Induced Pluripotent Stem Cells with Modifiable SIRT1 Metabolism Journal article
Cell Metabolism, 2019,Volume: 30,Issue: 2,Page: 385-401.e9
Authors:  Collin de l'Hortet,Alexandra;  Takeishi,Kazuki;  Guzman-Lepe,J.;  Morita,Kazutoyo;  Achreja,Abhinav;  Popovic,Branimir;  Wang,Yang;  Handa,Kan;  Mittal,Anjali;  Meurs,Noah;  Zhu,Z.;  Weinberg,F.;  Salomon,Michael;  Fox,I. J.;  Deng,Chu Xia;  Nagrath,Deepak;  Soto-Gutierrez,Alejandro
Favorite |  | TC[WOS]:22 TC[Scopus]:22 | Submit date:2020/09/16
cellular engineering  hepatic differentiation  human fatty liver  human iPSCs  liver metabolism  NAFLD  NASH  SIRT1  
Elevated Exogenous Pyruvate Potentiates Mesodermal Differentiation through Metabolic Modulation and AMPK/mTOR Pathway in Human Embryonic Stem Cells Journal article
STEM CELL REPORTS, 2019,Volume: 13,Issue: 2,Page: 338-351
Authors:  Chengcheng Song;  Faxiang Xu;  Zhili Ren;  Yumeng Zhang;  Ya Meng;  Yiqi Yang;  Shreyas Lingadahalli;  Edwin Cheung;  Gang Li;  Weiwei Liu;  Jianbo Wan;  Yang Zhao;  Guokai Chen
Favorite |  | TC[WOS]:5 TC[Scopus]:7 | Submit date:2020/04/22
Hescs  Pyruvate  Bmp4  Glycolysis  Tca Cycle  Ampk  Wnt  Metabolism  Mesoderm  Differentiation  
A genome-wide analysis of carbon catabolite repression in Schizosaccharomyces pombe Journal article
BMC GENOMICS, 2019,Volume: 20
Authors:  Dane Vassiliadis;  Koon Ho Wong;  Alex Andrianopoulos;  Brendon J. Monahan
Favorite |  | TC[WOS]:6 TC[Scopus]:6 | Submit date:2020/06/12
Schizosaccharomyces Pombe  Transcriptional Regulation  Carbon Metabolism  Carbon Catabolite Repression  Rst2  Rna-seq  Chip-seq Background  Tup11  Scr1  
Benefits of multiple micronutrient supplementation in heart failure:A comprehensive review Conference paper
CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION, Kunming, PEOPLES R CHINA, 2018-8
Authors:  Simona Dragan;  Florina Buleu;  Ruxandra Christodorescu;  Florin Cobzariu;  Stela Iurciuc;  Dana Velimirovici;  Jianbo Xiao;  Constantin Tudor Luca
Favorite |  | TC[WOS]:10 TC[Scopus]:10 | Submit date:2020/04/27
Heart Failure  Energetic Metabolism  Coenzyme Q10  Vitamin d  Micronutrient Supplementation  Comprehensive Review  
Inhibitory effects of anthocyanins on α-glucosidase activity Journal article
JOURNAL OF BERRY RESEARCH, 2019,Volume: 9,Issue: 1,Page: 109-123
Authors:  Zhang, Jiaojiao;  Xiao, Jianbo;  Giampieri, Francesca;  Forbes-Hernandez, Tamara Y;  Gasparrini, Massimiliano;  Afrin, Sadia;  Cianciosi, Danila;  Reboredo-Rodriguez, Patricia;  Battino, Maurizio;  Zheng, Xiaodong
Favorite |  | TC[WOS]:3 TC[Scopus]:3 | Submit date:2020/04/27
Anthocyanins  Not Glycosylated Forms  Glycosylated Forms  Inhibitors  Α-glucosidase  Sugar Metabolism  
The epigenetically downregulated factor CYGB suppresses breast cancer through inhibition of glucose metabolism Journal article
JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH, 2018,Volume: 37
Authors:  Feng, Yixiao;  Wu, Mingjun;  Li, Shuman;  He, Xiaoqian;  Tang, Jun;  Peng, Weiyan;  Zeng, Beilei;  Deng, Chuxia;  Ren, Guosheng;  Xiang, Tingxiu
Favorite |  | TC[WOS]:4 TC[Scopus]:6 | Submit date:2019/01/17
CYGB  GLUT1  HXK2  p53  Breast cancer  Metabolism  Glycolysis