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Iron overload induced by IRP2 gene knockout aggravates symptoms of Parkinson's disease Journal article
Neurochemistry International, 2020,Volume: 134
Authors:  Ci,Yun Zhe;  Li,Haiyan;  You,Lin Hao;  Jin,Yu;  Zhou,Rui;  Gao,Guofen;  Hoi,Maggie Pui Man;  Wang,Chunyan;  Chang,Yan Zhong;  Yu,Peng
Favorite |  | TC[WOS]:3 TC[Scopus]:4 | Submit date:2021/03/01
Astrocyte  DMT1  Iron  Iron regulatory protein 2  Parkinson's disease  
G-protein coupled receptor 55 agonists increase insulin secretion through inositol trisphosphate-mediated calcium release in pancreatic β-cells Journal article
European Journal of Pharmacology, 2019,Volume: 854,Page: 372-379
Authors:  Vong,Chi Teng;  Tseng,Hisa Hui Ling;  Kwan,Yiu Wa;  Lee,Simon Ming Yuen;  Hoi,Maggie Pui Man
Favorite |  | TC[WOS]:7 TC[Scopus]:8 | Submit date:2021/03/01
Calcium  GPR55  Inositol trisphosphate  Insulin secretion  Pancreatic β-cells  
A Danshensu-Tetramethylpyrazine Conjugate DT-010 Overcomes Multidrug Resistance in Human Breast Cancer Journal article
FRONTIERS IN PHARMACOLOGY, 2019,Volume: 10
Authors:  Xinhua Zhou;  Anqi Wang;  Liang Wang;  Jianhua Yin;  Li Wang;  Lijun Di;  Maggie Pui-Man Hoi;  Luchen Shan;  Xu Wu;  Yuqiang Wang
Favorite |  | TC[WOS]:4 TC[Scopus]:4 | Submit date:2020/05/21
Danshensu  Tetramethylpyrazine  Breast Cancer  Resistance  Glycolysis  P-glycoprotein  
Memantine improves cognitive function and alters hippocampal and cortical proteome in triple transgenic mouse model of Alzheimer’s disease Journal article
Experimental Neurobiology, 2019,Volume: 28,Issue: 3,Page: 390-403
Authors:  Zhou,Xinhua;  Wang,Liang;  Xiao,Wei;  Su,Zhiyang;  Zheng,Chengyou;  Zhang,Zaijun;  Wang,Yuqiang;  Xu,Benhong;  Yang,Xifei;  Hoi,Maggie Pui Man
Favorite |  | TC[WOS]:7 TC[Scopus]:6 | Submit date:2021/03/01
Alzheimer’s disease (AD)  MARK2  Memantine  Proteomic  
Neuroprotective Effects of BHDPC, a Novel Neuroprotectant, on Experimental Stroke by Modulating Microglia Polarization Journal article
ACS CHEMICAL NEUROSCIENCE, 2019,Volume: 10,Issue: 5,Page: 2434-2449
Authors:  Chuwen Li;  Yaqi Bian;  Yu Feng;  Fan Tang;  Liang Wang;  Maggie Pui Man Hoi;  Dan Ma;  Chao Zhao;  Simon Ming Yuen Lee
Favorite |  | TC[WOS]:12 TC[Scopus]:13 | Submit date:2020/01/16
Bhdpc  Ischemic Stroke  Microglia  Nf-κb  Creb  Pka  
Novel protective effect of O-1602 and abnormal cannabidiol, GPR55 agonists, on ER stress-induced apoptosis in pancreatic β-cells Journal article
Biomedicine and Pharmacotherapy, 2019,Volume: 111,Page: 1176-1186
Authors:  Vong,Chi Teng;  Tseng,Hisa Hui Ling;  Kwan,Yiu Wa;  Lee,Simon Ming Yuen;  Hoi,Maggie Pui Man
Favorite |  | TC[WOS]:7 TC[Scopus]:8 | Submit date:2021/03/01
CREB  ER stress  GPR55  β-Cell apoptosis  
Pinostrobin Exerts Neuroprotective Actions in Neurotoxin-Induced Parkinson's Disease Models through Nrf2 Induction Journal article
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 2018,Volume: 66,Issue: 31,Page: 8307-8318
Authors:  Li, Chuwen;  Tang, Benqin;  Feng, Yu;  Tang, Fan;  Hoi, Maggie Pui-Man;  Su, Ziren;  Lee, Simon Ming-Yuen
Favorite |  | TC[WOS]:23 TC[Scopus]:25 | Submit date:2018/10/31
Pinostrobin  Parkinson's Disease  Neurotoxin  Nrf2  
Schisantherin a attenuates neuroinflammation in activated microglia: Role of Nrf2 activation through ERK phosphorylation Journal article
Cellular Physiology and Biochemistry, 2018,Volume: 47,Issue: 5,Page: 1769-1784
Authors:  Li,Chuwen;  Chen,Tongkai;  Zhou,Hefeng;  Zhang,Chao;  Feng,Yu;  Tang,Fan;  Hoi,Maggie Pui Man;  He,Chengwei;  Zheng,Ying;  Lee,Simon Ming Yuen
Favorite |  | TC[WOS]:20 TC[Scopus]:21 | Submit date:2021/03/01
Microglia  Neuroinflammation  NF-κB  Nrf2  Schisantherin A  
A novel compound DT-010 protects against doxorubicin-induced cardiotoxicity in zebrafish and H9c2 cells by inhibiting reactive oxygen species-mediated apoptotic and autophagic pathways Journal article
EUROPEAN JOURNAL OF PHARMACOLOGY, 2018,Volume: 820,Page: 86-96
Authors:  Tang, Fan;  Zhou, Xinhua;  Wang, Liang;  Shan, Luchen;  Li, Chuwen;  Zhou, Hefeng;  Lee, Simon Ming-Yuen;  Hoi, Maggie Pui-Man
Favorite |  | TC[WOS]:25 TC[Scopus]:23 | Submit date:2018/10/30
Cardioprotection  Anti-oxidative Stress  Anti-apoptosis  Autophagy Regulation  Zebrafish Cardiotoxicity  H9c2 Cardiomyocytes  
Tanshinone I prevents atorvastatin-induced cerebral hemorrhage in zebrafish and stabilizes endothelial cell-cell adhesion by inhibiting. VE-cadherin internalization and actin-myosin contractility Journal article
PHARMACOLOGICAL RESEARCH, 2018,Volume: 128,Page: 389-398
Authors:  Huang, Bin;  Zhou, Zhong-Yan;  Li, Shang;  Huang, Xiao-Hui;  Tang, Jing-Yi;  Hoi, Maggie Pui Man;  Lee, Simon Ming Yuen
Favorite |  | TC[WOS]:9 TC[Scopus]:11 | Submit date:2018/10/30
Tanshinone i  Vascular Integrity  Endothelial Cell Adhesion  Hemorrhagic Stroke  Zebrafish  Huvecs