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Autophagy-regulating miRNAs: potential targets for obesity and related metabolic disorders Journal article
Drug Discovery Today, 2021
Authors:  Zhang,Tian;  Linghu,Ke Gang;  Lou,Ruohan;  Li,Zhengqiu;  Liu,Jingxin;  Li,Rongsong;  Qin,Zheng Hong;  Guo,Bing;  Lin,Ligen
Favorite |  | TC[WOS]:0 TC[Scopus]:0 | Submit date:2021/03/01
Small molecule-driven SIRT3-autophagy-mediated NLRP3 inflammasome inhibition ameliorates inflammatory crosstalk between macrophages and adipocytes Journal article
British Journal of Pharmacology, 2020,Volume: 177,Issue: 20,Page: 4645-4665
Authors:  Zhang,Tian;  Fang,Zhujun;  Linghu,Ke Gang;  Liu,Jingxin;  Gan,Lishe;  Lin,Ligen
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adipocytes  adipose tissue inflammation  autophagy  cycloartane triterpenoid  IL-1β, macrophages  NLRP3 inflammasome  
Interactions of antithrombotic herbal medicines with Western cardiovascular drugs Journal article
Pharmacological Research, 2020,Volume: 159
Authors:  Zuo,Hua Li;  Linghu,Ke Gang;  Wang,Ya Li;  Liu,Kun Meng;  Gao,Yan;  Yu,Hua;  Yang,Feng Qing;  Hu,Yuan Jia
Favorite |  | TC[WOS]:1 TC[Scopus]:1 | Submit date:2021/03/01
Antithrombotic herbal medicine  Butylidenephthalide (PubChem CID: 642376)  Cardiovascular disease  Cryptotanshinone (PubChem CID: 160254)  Herb−drug interaction  Network pharmacology  Salvianolic acid A (PubChem CID: 5281793)  Salvianolic acid C (PubChem CID: 13991590)  Senkyunolide C (PubChem CID: 642374)  Tanshinone I (PubChem CID: 114917)  Tanshinone IIA (PubChem CID: 164676)  Western drugs  
Sigesbeckia orientalis L. Extract Alleviated the Collagen Type II–Induced Arthritis Through Inhibiting Multi-Target–Mediated Synovial Hyperplasia and Inflammation Journal article
Frontiers in Pharmacology, 2020,Volume: 11
Authors:  Linghu,Ke Gang;  Xiong,Shi Hang;  Zhao,Guan Ding;  Zhang,Tian;  Xiong,Wei;  Zhao,Mingming;  Shen,Xiang Chun;  Xu,Wei;  Bian,Zhaoxiang;  Wang,Yitao;  Yu,Hua
Favorite |  | TC[WOS]:0 TC[Scopus]:0 | Submit date:2021/03/02
inflammation  MH7A  rheumatoid arthritis  Sigesbeckia orientalisL  SW982  synovial hyperplasia  
Sigesbeckia glabrescens Makino extract attenuated the collagen-induced arthritis through inhibiting the synovial hyperplasia and inflammation Journal article
Chinese Medicine (United Kingdom), 2020,Volume: 15,Issue: 1
Authors:  Ma,Qiu Shuo;  Linghu,Ke Gang;  Zhang,Tian;  Zhao,Guan Ding;  Xiong,Wei;  Xiong,Shi Hang;  Zhao,Mingming;  Xu,Wei;  Yu,Juan;  Yu,Hua
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Inflammation  Nuclear transcription factor-kappa B  Rheumnnatoid arthritis  Sigesbeckia glabrescens Makino  SW982  Synovial hyperplasia  
Comprehensive comparison on the anti-inflammatory effects of three species of Sigesbeckia plants based on NF-κB and MAPKs signal pathways in vitro Journal article
Journal of Ethnopharmacology, 2020,Volume: 250
Authors:  Linghu,Ke Gang;  Zhao,Guan Ding;  Xiong,Wei;  Sang,Wei;  Xiong,Shi Hang;  Tse,Anfernee Kai Wing;  Hu,Yuanjia;  Bian,Zhaoxiang;  Wang,Yitao;  Yu,Hua
Favorite |  | TC[WOS]:4 TC[Scopus]:4 | Submit date:2021/03/01
Anti-inflammation  MAPKs  NF-κB  Sigesbeckia glabrescens makino  Sigesbeckia orientalis L.  Sigesbeckia pubescens makino  
Leocarpinolide B attenuates LPS-induced inflammation on RAW264.7 macrophages by mediating NF-κB and Nrf2 pathways Journal article
European Journal of Pharmacology, 2020,Volume: 868
Authors:  Linghu,Ke Gang;  Ma,Qiu Shuo;  Zhao,Guan Ding;  Xiong,Wei;  Lin,Ligen;  Zhang,Qing Wen;  Bian,Zhaoxiang;  Wang,Yitao;  Yu,Hua
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Leocarpinolide B  Nuclear factor erythroid 2-related factor 2 (Nrf2)  Nuclear transcription factor-kappa B (NF-κB)  Rheumatoid arthritis (RA)  Sigesbeckiae herba (SH)  
Botany, traditional use, phytochemistry, pharmacology and toxicology of Sigesbeckiae Herba (Xixiancao): a review Journal article
Phytochemistry Reviews, 2020
Authors:  Tao,Hong Xun;  Zhao,Guan Ding;  Linghu,Ke Gang;  Xiong,Wei;  Sang,Wei;  Peng,Yu;  Wang,Yitao;  Yu,Hua
Favorite |  | TC[WOS]:1 TC[Scopus]:1 | Submit date:2021/03/02
Pharmacology  Phytochemistry  Sigesbeckiae Herba  Toxicology  Traditional use  
Dual-functional Brij-S20-modified nanocrystal formulation enhances the intestinal transport and oral bioavailability of berberine Journal article
INTERNATIONAL JOURNAL OF NANOMEDICINE, 2018,Volume: 13,Page: 3781-3793
Authors:  Xiong, Wei;  Sang, Wei;  Linghu, Ke Gang;  Zhong, Zhang Feng;  Cheang, Wai San;  Li, Juan;  Hu, Yuan Jia;  Yu, Hua;  Wang, Yi Tao
Favorite |  | TC[WOS]:7 TC[Scopus]:8 | Submit date:2018/10/30
Berberine  Poor Water Solubility  Pgp-mediated Drug Efflux  Brij  Nanocrystals