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Autophagy-regulating miRNAs: potential targets for obesity and related metabolic disorders Journal article
Drug Discovery Today, 2021
Authors:  Zhang,Tian;  Linghu,Ke Gang;  Lou,Ruohan;  Li,Zhengqiu;  Liu,Jingxin;  Li,Rongsong;  Qin,Zheng Hong;  Guo,Bing;  Lin,Ligen
Favorite |  | TC[WOS]:0 TC[Scopus]:0 | Submit date:2021/03/01
Small molecule-driven SIRT3-autophagy-mediated NLRP3 inflammasome inhibition ameliorates inflammatory crosstalk between macrophages and adipocytes Journal article
British Journal of Pharmacology, 2020,Volume: 177,Issue: 20,Page: 4645-4665
Authors:  Zhang,Tian;  Fang,Zhujun;  Linghu,Ke Gang;  Liu,Jingxin;  Gan,Lishe;  Lin,Ligen
Favorite |  | TC[WOS]:9 TC[Scopus]:9 | Submit date:2021/03/01
adipocytes  adipose tissue inflammation  autophagy  cycloartane triterpenoid  IL-1β, macrophages  NLRP3 inflammasome  
Interactions of antithrombotic herbal medicines with Western cardiovascular drugs Journal article
Pharmacological Research, 2020,Volume: 159
Authors:  Zuo,Hua Li;  Linghu,Ke Gang;  Wang,Ya Li;  Liu,Kun Meng;  Gao,Yan;  Yu,Hua;  Yang,Feng Qing;  Hu,Yuan Jia
Favorite |  | TC[WOS]:2 TC[Scopus]:2 | Submit date:2021/03/01
Antithrombotic Herbal Medicine  Butylidenephthalide (Pubchem Cid: 642376)  Cardiovascular Disease  Cryptotanshinone (Pubchem Cid: 160254)  Herb−drug Interaction  Network Pharmacology  Salvianolic ACid a (Pubchem Cid: 5281793)  Salvianolic ACid c (Pubchem Cid: 13991590)  Senkyunolide c (Pubchem Cid: 642374)  Tanshinone i (Pubchem Cid: 114917)  Tanshinone Iia (Pubchem Cid: 164676)  Western Drugs  
Sigesbeckia orientalis L. Extract Alleviated the Collagen Type II–Induced Arthritis Through Inhibiting Multi-Target–Mediated Synovial Hyperplasia and Inflammation Journal article
Frontiers in Pharmacology, 2020,Volume: 11
Authors:  Linghu,Ke Gang;  Xiong,Shi Hang;  Zhao,Guan Ding;  Zhang,Tian;  Xiong,Wei;  Zhao,Mingming;  Shen,Xiang Chun;  Xu,Wei;  Bian,Zhaoxiang;  Wang,Yitao;  Yu,Hua
Favorite |  | TC[WOS]:0 TC[Scopus]:0 | Submit date:2021/03/02
Inflammation  Mh7a  Rheumatoid Arthritis  Sigesbeckia Orientalisl  Sw982  Synovial Hyperplasia  
Sigesbeckia glabrescens Makino extract attenuated the collagen-induced arthritis through inhibiting the synovial hyperplasia and inflammation Journal article
Chinese Medicine (United Kingdom), 2020,Volume: 15,Issue: 1
Authors:  Ma,Qiu Shuo;  Linghu,Ke Gang;  Zhang,Tian;  Zhao,Guan Ding;  Xiong,Wei;  Xiong,Shi Hang;  Zhao,Mingming;  Xu,Wei;  Yu,Juan;  Yu,Hua
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Inflammation  Nuclear Transcription Factor-kappa b  Rheumnnatoid Arthritis  Sigesbeckia Glabrescens Makino  Sw982  Synovial Hyperplasia  
Comprehensive comparison on the anti-inflammatory effects of three species of Sigesbeckia plants based on NF-κB and MAPKs signal pathways in vitro Journal article
Journal of Ethnopharmacology, 2020,Volume: 250
Authors:  Linghu,Ke Gang;  Zhao,Guan Ding;  Xiong,Wei;  Sang,Wei;  Xiong,Shi Hang;  Tse,Anfernee Kai Wing;  Hu,Yuanjia;  Bian,Zhaoxiang;  Wang,Yitao;  Yu,Hua
Favorite |  | TC[WOS]:5 TC[Scopus]:5 | Submit date:2021/03/01
Anti-inflammation  Mapks  Nf-κb  Sigesbeckia Glabrescens Makino  Sigesbeckia OrientaL.s L.  Sigesbeckia Pubescens Makino  
Leocarpinolide B attenuates LPS-induced inflammation on RAW264.7 macrophages by mediating NF-κB and Nrf2 pathways Journal article
European Journal of Pharmacology, 2020,Volume: 868
Authors:  Linghu,Ke Gang;  Ma,Qiu Shuo;  Zhao,Guan Ding;  Xiong,Wei;  Lin,Ligen;  Zhang,Qing Wen;  Bian,Zhaoxiang;  Wang,Yitao;  Yu,Hua
Favorite |  | TC[WOS]:4 TC[Scopus]:5 | Submit date:2021/03/01
Leocarpinolide b  Nuclear Factor Erythroid 2-related Factor 2 (Nrf2)  Nuclear Transcription Factor-kappa b (Nf-κb)  Rheumatoid Arthritis (Ra)  Sigesbeckiae Herba (Sh)  
Botany, traditional use, phytochemistry, pharmacology and toxicology of Sigesbeckiae Herba (Xixiancao): a review Journal article
Phytochemistry Reviews, 2020
Authors:  Tao,Hong Xun;  Zhao,Guan Ding;  Linghu,Ke Gang;  Xiong,Wei;  Sang,Wei;  Peng,Yu;  Wang,Yitao;  Yu,Hua
Favorite |  | TC[WOS]:1 TC[Scopus]:1 | Submit date:2021/03/02
Pharmacology  Phytochemistry  Sigesbeckiae Herba  Toxicology  Traditional Use  
Deciphering the Pharmacological Mechanisms of the Huayu-Qiangshen-Tongbi Formula Through Integrating Network Pharmacology and In Vitro Pharmacological Investigation Journal article
FRONTIERS IN PHARMACOLOGY, 2019,Volume: 10
Authors:  Zihao Wang;  Ke-Gang Linghu;  Yuanjia Hu;  Huali Zuo;  Hao Yi;  Shi-Hang Xiong;  Jinjian Lu;  Ging Chan;  Hua Yu;  Run-Yue Huang
Favorite |  | TC[WOS]:5 TC[Scopus]:6 | Submit date:2019/12/04
Rheumatoid Arthritis  Network Pharmacology  Traditional Chinese Medicine  Huayu-qiangshen-tongbi Formula  In Vitro Validation  
Immunomodulatory effects of a new whole ingredients extract from Astragalus: a combined evaluation on chemistry and pharmacology Journal article
CHINESE MEDICINE, 2019,Volume: 14
Authors:  Zhi Xin Li;  Guan Ding Zhao;  Wei Xiong;  Ke Gang Linghu;  Qiu Shuo Ma;  Wai San Cheang;  Hua Yu;  Yitao Wang
Favorite |  | TC[WOS]:8 TC[Scopus]:8 | Submit date:2020/03/10
Whole Ingredients Extract  Chemical Integrity  Immunomodulation  Astragali Radix