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Pharmacological review of isobavachalcone, a naturally occurring chalcone Journal article
Pharmacological Research, 2021
Authors:  Wang,Miaojuan;  Lin,Ligen;  Lu,Jin Jian;  Chen,Xiuping
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Isobavachalcone  Molecular targets  Pharmacokinetic  Pharmacology  
Autophagy-regulating miRNAs: potential targets for obesity and related metabolic disorders Journal article
Drug Discovery Today, 2021
Authors:  Zhang,Tian;  Linghu,Ke Gang;  Lou,Ruohan;  Li,Zhengqiu;  Liu,Jingxin;  Li,Rongsong;  Qin,Zheng Hong;  Guo,Bing;  Lin,Ligen
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Sesquiterpene lactone dimers from Artemisia lavandulifolia inhibit interleukin-1β production in macrophages through activating autophagy Journal article
Bioorganic Chemistry, 2020,Volume: 105
Authors:  Wang,Qiaoqiao;  Zhang,Tian;  Ke,Chang Qiang;  Tang,Chunping;  Yao,Sheng;  Lin,Ligen;  Ye,Yang
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Artemisia lavandulifolia  Autophagy  IL-1β  NLRP3  Sesquiterpene lactone dimers  
The drug likeness analysis of anti-inflammatory clerodane diterpenoids Journal article
Chinese Medicine (United Kingdom), 2020,Volume: 15,Issue: 1
Authors:  Feng,Zheling;  Cao,Jun;  Zhang,Qingwen;  Lin,Ligen
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Anti-inflammation  Clerodane diterpenoids  Drug-likeness  SwissADME  
Pimarane diterpenoids from the seeds of caesalpinia minax as PTP1B inhibitors and insulin sensitizers Journal article
Molecules, 2020,Volume: 25,Issue: 20
Authors:  Xu,Yunshao;  Feng,Zheling;  Zhang,Tian;  Lv,Peng;  Cao,Jun;  Li,Dan;  Peng,Cheng;  Lin,Ligen
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C2C12 myotubes  Caesalpinia minax  Glucose uptake  Pimarane diterpenoids  PTP1B  
Small molecule-driven SIRT3-autophagy-mediated NLRP3 inflammasome inhibition ameliorates inflammatory crosstalk between macrophages and adipocytes Journal article
British Journal of Pharmacology, 2020,Volume: 177,Issue: 20,Page: 4645-4665
Authors:  Zhang,Tian;  Fang,Zhujun;  Linghu,Ke Gang;  Liu,Jingxin;  Gan,Lishe;  Lin,Ligen
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adipocytes  adipose tissue inflammation  autophagy  cycloartane triterpenoid  IL-1β, macrophages  NLRP3 inflammasome  
Anti-inflammatory property of the essential oil from cinnamomum camphora (Linn.) presl leaves and the evaluation of its underlying mechanism by using metabolomics analysis Journal article
Molecules, 2020,Volume: 25,Issue: 20
Authors:  Chen,Jiali;  Tang,Cailin;  Zhou,Yang;  Zhang,Rongfei;  Ye,Shaoxia;  Zhao,Zhimin;  Lin,Ligen;  Yang,Depo
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Anti-inflammation  BV2 microglial cells  Cinnamomum camphora (Linn.) Presl  Essential oil  Glycolysis  Metabolomics  
Targeted isolation of two disesquiterpenoid macrocephadiolides A and B from: Ainsliaea macrocephala using a molecular networking-based dereplication strategy Journal article
Organic Chemistry Frontiers, 2020,Volume: 7,Issue: 12,Page: 1481-1489
Authors:  Ren,Yong Mei;  Ren,Yong Mei;  Ren,Yong Mei;  Zhou,Shuai Zhen;  Zhang,Tian;  Qian,Meijia;  Zhang,Rui;  Yao,Sheng;  Zhu,Hong;  Tang,Chunping;  Lin,Ligen;  Ye,Yang;  Ye,Yang;  Ye,Yang
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Tricarabrols A-C, three anti-inflammatory sesquiterpene lactone trimers featuring a methylene-tethered linkage from: Carpesium faberi Journal article
Organic Chemistry Frontiers, 2020,Volume: 7,Issue: 11,Page: 1374-1382
Authors:  Yuan,Jie;  Wen,Xuelan;  Ke,Chang Qiang;  Zhang,Tian;  Lin,Ligen;  Yao,Sheng;  Goodpaster,Jason D.;  Tang,Chunping;  Ye,Yang
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Quantitative Proteomics Reveals Cellular Off-Targets of a DDR1 Inhibitor Journal article
ACS Medicinal Chemistry Letters, 2020,Volume: 11,Issue: 4,Page: 535-540
Authors:  Xu,Jiaqian;  Zhang,Zhang;  Lin,Ligen;  Sun,Hongyan;  White,Lorenzo V.;  Ding,Ke;  Li,Zhengqiu
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bioimaging  chemoproteomics  DDR1  photoaffinity labeling  target identification