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Synthesis, biological evaluation and structure-activity relationship of novel dichloroacetophenones targeting pyruvate dehydrogenase kinases with potent anticancer activity Journal article
European Journal of Medicinal Chemistry, 2021,Volume: 214
Authors:  Xu,Biao;  Wang,Zhi Peng;  Liu,Qingwang;  Yang,Xiaohong;  Li,Xuemin;  Huang,Ding;  Qiu,Yanfei;  Tam,Kin Yip;  Zhang,Shao Lin;  He,Yun
Favorite |  | TC[WOS]:0 TC[Scopus]:0 | Submit date:2021/03/04
Cancer metabolism  Proliferation  Pyruvate dehydrogenase kinase  Structure-activity relationship  
Upregulation of amplified in breast cancer 1 contributes to pancreatic ductal adenocarcinoma progression and vulnerability to blockage of hedgehog activation Journal article
Theranostics, 2021,Volume: 11,Issue: 4,Page: 1672-1689
Authors:  Li,Licen;  Bao,Jiaolin;  Wang,Haitao;  Lei,Josh Haipeng;  Peng,Cheng;  Zeng,Jianming;  Hao,Wenhui;  Zhang,Xu;  Xu,Xiaoling;  Yu,Chundong;  Deng,Chu Xia;  Chen,Qiang
Favorite |  | TC[WOS]:1 TC[Scopus]:0 | Submit date:2021/03/02
Aib1  Ecm  Hedgehog  Mafb  Pdac  
Dstyk mutation leads to congenital scoliosis-like vertebral malformations in zebrafish via dysregulated mTORC1/TFEB pathway Journal article
Nature Communications, 2020,Volume: 11,Issue: 1
Authors:  Sun,Xianding;  Zhou,Yang;  Zhang,Ruobin;  Wang,Zuqiang;  Xu,Meng;  Zhang,Dali;  Huang,Junlan;  Luo,Fengtao;  Li,Fangfang;  Ni,Zhenhong;  Zhou,Siru;  Chen,Hangang;  Chen,Shuai;  Chen,Liang;  Du,Xiaolan;  Chen,Bo;  Huang,Haiyang;  Liu,Peng;  Yin,Liangjun;  Qiu,Juhui;  Chen,Di;  Deng,Chuxia;  Xie,Yangli;  Luo,Lingfei;  Chen,Lin
Favorite |  | TC[WOS]:4 TC[Scopus]:5 | Submit date:2020/09/16
Development of a comprehensive method combining UHPLC-CAD fingerprint, multi-components quantitative analysis for quality evaluation of Zishen Yutai Pills: A step towards quality control of Chinese patent medicine Journal article
Journal of Pharmaceutical and Biomedical Analysis, 2020,Volume: 191
Authors:  Cao,Jiliang;  Lei,Ting;  Wu,Sijia;  Li,Hongyi;  Deng,Yun;  Lin,Ruizhen;  Ning,Na;  Geng,Chunxian;  Wang,Shengpeng;  Wu,Xu;  Li,Peng;  Wang,Yitao
Favorite |  | TC[WOS]:0 TC[Scopus]:0 | Submit date:2021/03/01
Chemical Characterization  Chemical Fingerprint  Multi-components Quantitative Analysis  Quality Evaluation  Zishen Yutai Pills  
Multiple fingerprint profiling for quality evaluation of polysaccharides and related biological activity analysis of Chinese patent drugs: Zishen Yutai Pills as a case study Journal article
Journal of Ethnopharmacology, 2020,Volume: 260
Authors:  Li,Hongyi;  Cao,Jiliang;  Wu,Xu;  Deng,Yun;  Ning,Na;  Geng,Chunxian;  Lei,Ting;  Lin,Ruizhen;  Wu,Dingtao;  Wang,Shengpeng;  Li,Peng;  Wang,Yitao
Favorite |  | TC[WOS]:7 TC[Scopus]:4 | Submit date:2021/03/01
Biological Activities  Multi-fingerprint  Polysaccharides  Zishen Yutai Pills  
Pimarane diterpenoids from the seeds of caesalpinia minax as PTP1B inhibitors and insulin sensitizers Journal article
Molecules, 2020,Volume: 25,Issue: 20
Authors:  Xu,Yunshao;  Feng,Zheling;  Zhang,Tian;  Lv,Peng;  Cao,Jun;  Li,Dan;  Peng,Cheng;  Lin,Ligen
Favorite |  | TC[WOS]:1 TC[Scopus]:0 | Submit date:2021/03/01
C2C12 myotubes  Caesalpinia minax  Glucose uptake  Pimarane diterpenoids  PTP1B  
An integrated microbiome and metabolomic analysis identifies immunoenhancing features of Ganoderma lucidum spores oil in mice Journal article
Pharmacological Research, 2020,Volume: 158
Authors:  Wu,Xu;  Cao,Jiliang;  Li,Mingxing;  Yao,Peifen;  Li,Hongyi;  Xu,Wendong;  Yuan,Cheng;  Liu,Juyan;  Wang,Shengpeng;  Li,Peng;  Wang,Yitao
Favorite |  | TC[WOS]:1 TC[Scopus]:1 | Submit date:2021/03/01
Ganoderma Lucidum  Gut Microbiota  Immunity  Metabolomics  Spores Oil  
Effective Surface Ligand-Concentration Tuning of Deep-Blue Luminescent FAPbBr3Nanoplatelets with Enhanced Stability and Charge Transport Journal article
ACS Applied Materials and Interfaces, 2020,Volume: 12,Issue: 28,Page: 31863-31874
Authors:  Peng,Shaomin;  Wen,Zuoliang;  Ye,Taikang;  Xiao,Xiangtian;  Wang,Kaiyang;  Xia,Junmin;  Sun,Jiayun;  Zhang,Tianqi;  Mei,Guanding;  Liu,Haochen;  Xu,Bing;  Li,Xiaojun;  Chen,Rui;  Xing,Guichuan;  Wang,Kai;  Tang,Zikang
Favorite |  | TC[WOS]:6 TC[Scopus]:6 | Submit date:2021/03/11
charge transport  deep-blue  FAPbBr3nanoplatelets  ligand-concentration tuning  
BRCA1 Deficiency Impairs Mitophagy and Promotes Inflammasome Activation and Mammary Tumor Metastasis Journal article
Advanced Science, 2020,Volume: 7,Issue: 6
Authors:  Chen,Qiang;  Lei,Josh Haipeng;  Bao,Jiaolin;  Wang,Haitao;  Hao,Wenhui;  Li,Licen;  Peng,Cheng;  Masuda,Takaaki;  Miao,Kai;  Xu,Jun;  Xu,Xiaoling;  Deng,Chu Xia
Favorite |  | TC[WOS]:10 TC[Scopus]:11 | Submit date:2020/09/16
Atm-ampk-drp1  Brca1  Inflammasomes  Mitochondrial Dynamics  Mitophagy  
Lysyl oxidase promotes liver metastasis of gastric cancer via facilitating the reciprocal interactions between tumor cells and cancer associated fibroblasts Journal article
EBioMedicine, 2019,Volume: 49,Page: 157-171
Authors:  Li,Qing;  Zhu,Chun Chao;  Ni,Bo;  Zhang,Zi Zhen;  Jiang,Shu Heng;  Hu,Li Peng;  Wang,Xu;  Zhang,Xiao Xin;  Huang,Pei Qi;  Yang,Qin;  Li,Jun;  Gu,Jian Ren;  Xu,Jia;  Luo,Kathy Qian;  Zhao,Gang;  Zhang,Zhi Gang
Favorite |  | TC[WOS]:13 TC[Scopus]:12 | Submit date:2021/03/02
CAFs  Gastric cancer  Liver metastasis  LOX  Warburg effect