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The role of FOXOs and autophagy in cancer and metastasis—Implications in therapeutic development Journal article
Medicinal Research Reviews, 2020,Volume: 40,Issue: 6,Page: 2089-2113
Authors:  Farhan,Mohd;  Silva,Marta;  Li,Shuai;  Yan,Fengxia;  Fang,Jiankang;  Peng,Tangming;  Hu,Jim;  Tsao,Ming Sound;  Little,Peter;  Zheng,Wenhua
Favorite |  | TC[WOS]:2 TC[Scopus]:2 | Submit date:2021/03/04
autophagy  cancer  FOXO proteins  metastasis  
Artemisinin protects motoneurons against axotomy-induced apoptosis through activation of the PKA-Akt signaling pathway and promotes neural stem/progenitor cells differentiation into NeuN+ neurons Journal article
Pharmacological Research, 2020,Volume: 159
Authors:  Liu,Linlin;  Zhao,Xia;  Silva,Marta;  Li,Shuai;  Xing,Xingan;  Zheng,Wenhua
Favorite |  | TC[WOS]:0 TC[Scopus]:0 | Submit date:2021/03/04
Artemisinin  Brachial plexus axotomy  Inflammatory response  Motoneurons  
Pristimerin-induced uveal melanoma cell death via inhibiting PI3K/Akt/FoxO3a signalling pathway Journal article
Journal of Cellular and Molecular Medicine, 2020,Volume: 24,Issue: 11,Page: 6208-6219
Authors:  Yan,Fengxia;  Liao,Rifang;  Silva,Marta;  Li,Shuai;  Jiang,Yizhou;  Peng,Tangming;  Lazarovici,Philip;  Zheng,Wenhua
Favorite |  | TC[WOS]:2 TC[Scopus]:2 | Submit date:2021/03/04
cell death  FoxO3a  nuclear accumulation  Pristimerin  uveal melanoma  
Foxo3a suppresses neuropeptide w expression in neuronal cells and in rat hypothalamus and its implication in hypothalamic-pituitary-adrenal (HPA) axis Journal article
International Journal of Biological Sciences, 2020,Volume: 16,Issue: 15,Page: 2775-2787
Authors:  Yan,Fengxia;  Wang,Rikang;  Li,Shuai;  Zhao,Xia;  Jiang,Yizhou;  Liu,Linlin;  Fang,Jiankang;  Zhen,Xuechu;  Lazarovici,Philip;  Zheng,Wenhua
Favorite |  | TC[WOS]:0 TC[Scopus]:0 | Submit date:2021/03/04
FoxO3a  Glucocorticoids  HPA axis dysfunction  Hypothalamus  Neuropeptide W (NPW)  
Artemisinin improved neuronal functions in Alzheimer's disease animal model 3xtg mice and neuronal cells via stimulating the ERK/CREB signaling pathway Journal article
Aging and Disease, 2020,Volume: 11,Issue: 4,Page: 801-819
Authors:  Zhao,Xia;  Li,Shuai;  Gaur,Uma;  Zheng,Wenhua
Favorite |  | TC[WOS]:2 TC[Scopus]:3 | Submit date:2021/03/04
3×Tg mice  Alzheimer's disease  Amyloid beta  Artemisinin  Cognitive behavior  SH-SY5Ycells  
Protective mechanism of artemisinin on rat bone marrow-derived mesenchymal stem cells against apoptosis induced by hydrogen peroxide via activation of c-Raf-Erk1/2-p90rsk-CREB pathway Journal article
Stem Cell Research and Therapy, 2019,Volume: 10,Issue: 1
Authors:  Fang,Jiankang;  Zhao,Xia;  Li,Shuai;  Xing,Xingan;  Wang,Haitao;  Lazarovici,Philip;  Zheng,Wenhua
Favorite |  | TC[WOS]:11 TC[Scopus]:11 | Submit date:2021/03/04
Apoptosis  Artemisinin  Bone marrow mesenchymal stem cells  CREB  Erk1/2  p90rsk  Phosphorylation  Protection  Raf  ROS  
Artemisinin attenuated hydrogen peroxide (H2o2)-induced oxidative injury in SH-SY5Y and hippocampal neurons via the activation of AMPK pathway Journal article
International Journal of Molecular Sciences, 2019,Volume: 20,Issue: 11
Authors:  Zhao,Xia;  Fang,Jiankang;  Li,Shuai;  Gaur,Uma;  Xing,Xingan;  Wang,Huan;  Zheng,Wenhua
Favorite |  | TC[WOS]:10 TC[Scopus]:16 | Submit date:2021/03/04
AMPK pathway  Artemisinin  H2O2  Hippocampal neurons  SH-SY5Y cells  
Artemisinin protects human retinal pigmented epithelial cells against hydrogen peroxide-induced oxidative damage by enhancing the activation of AMP-active protein kinase Journal article
International Journal of Biological Sciences, 2019,Volume: 15,Issue: 9,Page: 2016-2028
Authors:  Li,Shuai;  Chaudhary,Shubhash Chandra;  Zhao,Xia;  Gaur,Uma;  Fang,Jiankang;  Yan,Fengxia;  Zheng,Wenhua
Favorite |  | TC[WOS]:2 TC[Scopus]:3 | Submit date:2021/03/04
AMPK  Artemisinin  Oxidative stress  Retinal pigment epithelial cells  
Artemether Activation of AMPK/GSK3 β (ser9)/Nrf2 Signaling Confers Neuroprotection towards β- Amyloid-Induced Neurotoxicity in 3xTg Alzheimer's Mouse Model Journal article
Oxidative Medicine and Cellular Longevity, 2019,Volume: 2019
Authors:  Li,Shuai;  Zhao,Xia;  Lazarovici,Philip;  Zheng,Wenhua
Favorite |  | TC[WOS]:8 TC[Scopus]:11 | Submit date:2021/03/04
Berberine Protects Human Retinal Pigment Epithelial Cells from Hydrogen Peroxide-Induced Oxidative Damage through Activation of AMPK Journal article
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2018,Volume: 19,Issue: 6
Authors:  Li, Shuai;  Gaur, Uma;  Chong, Cheong-Meng;  Lin, Shaofen;  Fang, Jiankang;  Zeng, Zhiwen;  Wang, Haitao;  Zheng, Wenhua
Favorite |  | TC[WOS]:13 TC[Scopus]:15 | Submit date:2018/10/30
Berberine  Age-related Macular Degeneration  D407 Cells  Ampk