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Zebrafish: A Promising Model for Evaluating the Toxicity of Carbon Dot-Based Nanomaterials Journal article
ACS Applied Materials and Interfaces, 2020,Volume: 12,Issue: 43,Page: 49012-49020
Authors:  Liu，Wei;  Huang，Gang;  Su，Xiaoying;  Li，Siyi;  Wang，Qun;  Zhao，Yuying;  Liu，Yao;  Luo，Jingshan;  Li，Ye;  Li，Chuwen;  Yuan，Dongsheng;  Hong，Honghai;  Chen，Xiaojia;  Chen，Tongkai
Favorite |  | TC[WOS]:2 TC[Scopus]:2 | Submit date：2021/03/02
carbon nanomaterials  developmental neurotoxicity  dopamine  nanotoxicology  zebrafish (Danio rerio)  
Oxyphylla a promotes degradation of α-synuclein for neuroprotection via activation of immunoproteasome Journal article
Aging and Disease, 2020,Volume: 11,Issue: 3,Page: 559-574
Authors:  Zhou，Hefeng;  Li，Shengnan;  Li，Chuwen;  Yang，Xuanjun;  Li，Haitao;  Zhong，Hanbing;  Lu，Jia Hong;  Lee，Simon Ming Yuen
Favorite |  | TC[WOS]:1 TC[Scopus]:1 | Submit date：2021/03/01
Degradation  Neuroprotection  Parkinson's disease  Proteasome  α-synuclein  
Tetramethylpyrazine Analogue T-006 Promotes the Clearance of Alpha-synuclein by Enhancing Proteasome Activity in Parkinson’s Disease Models Journal article
Neurotherapeutics, 2019,Volume: 16,Issue: 4,Page: 1225-1236
Authors:  Zhou，Hefeng;  Shao，Min;  Guo，Baojian;  Li，Chuwen;  Lu，Yucong;  Yang，Xuanjun;  ShengnanLi，;  Li，Haitao;  Zhu，Qi;  Zhong，Hanbing;  Wang，Yuqiang;  Zhang，Zaijun;  Lu，Jiahong;  Lee，Simon Ming Yuen
Favorite |  | TC[WOS]:7 TC[Scopus]:7 | Submit date：2021/03/01
Degradation  LMP7  Parkinson’s disease  Proteasome activity  α-synuclein  
Tetramethylpyrazine Analogue T-006 Exerts Neuroprotective Effects against 6-Hydroxydopamine-Induced Parkinson's Disease In Vitro and In Vivo Journal article
Oxidative Medicine and Cellular Longevity, 2019,Volume: 2019
Authors:  Zhou，Hefeng;  Shao，Min;  Yang，Xuanjun;  Li，Chuwen;  Cui，Guozhen;  Gao，Cheng;  Di，Lijun;  Zhong，Hanbing;  Wang，Yuqiang;  Zhang，Zaijun;  Lee，Simon Ming Yuen
Favorite |  | TC[WOS]:5 TC[Scopus]:5 | Submit date：2021/03/01
Pinostrobin Exerts Neuroprotective Actions in Neurotoxin-Induced Parkinson's Disease Models through Nrf2 Induction Journal article
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 2018,Volume: 66,Issue: 31,Page: 8307-8318
Authors:  Li, Chuwen;  Tang, Benqin;  Feng, Yu;  Tang, Fan;  Hoi, Maggie Pui-Man;  Su, Ziren;  Lee, Simon Ming-Yuen
Favorite |  | TC[WOS]:18 TC[Scopus]:20 | Submit date：2018/10/31
Pinostrobin  Parkinson's Disease  Neurotoxin  Nrf2  
Schisantherin a attenuates neuroinflammation in activated microglia: Role of Nrf2 activation through ERK phosphorylation Journal article
Cellular Physiology and Biochemistry, 2018,Volume: 47,Issue: 5,Page: 1769-1784
Authors:  Li，Chuwen;  Chen，Tongkai;  Zhou，Hefeng;  Zhang，Chao;  Feng，Yu;  Tang，Fan;  Hoi，Maggie Pui Man;  He，Chengwei;  Zheng，Ying;  Lee，Simon Ming Yuen
Favorite |  | TC[WOS]:20 TC[Scopus]:21 | Submit date：2021/03/01
Microglia  Neuroinflammation  NF-κB  Nrf2  Schisantherin A  
BHDPC Is a Novel Neuroprotectant That Provides Anti-neuroinflammatory and Neuroprotective Effects by Inactivating NF-kappa B and Activating PKA/CREB Journal article
FRONTIERS IN PHARMACOLOGY, 2018,Volume: 9
Authors:  Li, Chuwen;  Chen, Tongkai;  Zhou, Hefeng;  Feng, Yu;  Hoi, Maggie P. M.;  Ma, Dan;  Zhao, Chao;  Zheng, Ying;  Lee, Simon M. Y.
Favorite |  | TC[WOS]:8 TC[Scopus]:8 | Submit date：2018/10/30
Bhdpc  Neuroinflammation  Microglia  Nf-kappa b  Creb  Pka  
Inhibitory Effects of Betulinic Acid on LPS-Induced Neuroinflammation Involve M2 Microglial Polarization via CaMKK beta-Dependent AMPK Activation Journal article
FRONTIERS IN MOLECULAR NEUROSCIENCE, 2018,Volume: 11
Authors:  Li, Chuwen;  Zhang, Chao;  Zhou, Hefeng;  Feng, Yu;  Tang, Fan;  Hoi, Maggie P. M.;  He, Chengwei;  Ma, Dan;  Zhao, Chao;  Lee, Simon M. Y.
Favorite |  | TC[WOS]:29 TC[Scopus]:29 | Submit date：2018/10/30
Amp-activated Protein Kinase  Betulinic Acid  Calmodulin-dependent Protein Kinase Beta  Microglia Polarization  Neuroinflammation  
A novel compound DT-010 protects against doxorubicin-induced cardiotoxicity in zebrafish and H9c2 cells by inhibiting reactive oxygen species-mediated apoptotic and autophagic pathways Journal article
EUROPEAN JOURNAL OF PHARMACOLOGY, 2018,Volume: 820,Page: 86-96
Authors:  Tang, Fan;  Zhou, Xinhua;  Wang, Liang;  Shan, Luchen;  Li, Chuwen;  Zhou, Hefeng;  Lee, Simon Ming-Yuen;  Hoi, Maggie Pui-Man
Favorite |  | TC[WOS]:23 TC[Scopus]:22 | Submit date：2018/10/30
Cardioprotection  Anti-oxidative Stress  Anti-apoptosis  Autophagy Regulation  Zebrafish Cardiotoxicity  H9c2 Cardiomyocytes  
Schisantherin A Attenuates Neuroinflammation in Activated Microglia: Role of Nrf2 Activation Through ERK Phosphorylation Journal article
CELLULAR PHYSIOLOGY AND BIOCHEMISTRY, 2018,Volume: 47,Issue: 5,Page: 1769-1784
Authors:  Li, Chuwen;  Chen, Tongkai;  Zhou, Hefeng;  Zhang, Chao;  Feng, Yu;  Tang, Fan;  Hoi, Maggie Pui-Man;  He, Chengwei;  Zheng, Ying;  Lee, Simon Ming-Yuen
Favorite |  | TC[WOS]:20 TC[Scopus]:21 | Submit date：2018/10/30
Schisantherin a  Neuroinflammation  Microglia  Nrf2  Nf-kappa b