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Pharmacological inhibition of KDM5A for cancer treatment Journal article
European Journal of Medicinal Chemistry, 2021,Volume: 226
Authors:  Yang, Guan Jun;  Wu, Jia;  Miao, Liang;  Zhu, Ming Hui;  Zhou, Qian Jin;  Lu, Xin Jiang;  Lu, Jian Fei;  Leung, Chung Hang;  Ma, Dik Lung;  Chen, Jiong
Favorite |  | TC[WOS]:0 TC[Scopus]:0 | Submit date:2021/12/08
Cancer Therapy  Drug Resistance  Histone Methylation  Lysine-specific Demethylase 5a  Screening Methods  
A review on the emerging roles of pyruvate kinase M2 in anti-leukemia therapy Journal article
International Journal of Biological Macromolecules, 2021,Volume: 193,Page: 1499-1506
Authors:  Yang, Guan Jun;  Wu, Jia;  Leung, Chung Hang;  Ma, Dik Lung;  Chen, Jiong
Favorite |  | TC[WOS]:0 TC[Scopus]:0 | Submit date:2022/01/14
Leukemia  Modulators  Pyruvate Kinase M2  
A small molecule HIF-1α stabilizer that accelerates diabetic wound healing Journal article
Nature Communications, 2021,Volume: 12,Issue: 1
Authors:  Li, Guodong;  Ko, Chung Nga;  Li, Dan;  Yang, Chao;  Wang, Wanhe;  Yang, Guan Jun;  Di Primo, Carmelo;  Wong, Vincent Kam Wai;  Xiang, Yaozu;  Lin, Ligen;  Ma, Dik Lung;  Leung, Chung Hang
Favorite |  | TC[WOS]:1 TC[Scopus]:5 | Submit date:2021/12/09
Application of metal–organic framework for the adsorption and detection of food contamination Journal article
TrAC - Trends in Analytical Chemistry, 2021,Volume: 143
Authors:  Wu, Ke Jia;  Wu, Chun;  Fang, Min;  Ding, Beibei;  Liu, Pin Pin;  Zhou, Meng Xin;  Gong, Zhi Yong;  Ma, Dik Lung;  Leung, Chung Hang
Favorite |  | TC[WOS]:0 TC[Scopus]:1 | Submit date:2021/12/08
Food contamination  Food security  Metal-organic frameworks  Sensors  Sorbent material  
An optimized BRD4 inhibitor effectively eliminates NF-κB-driven triple-negative breast cancer cells Journal article
Bioorganic Chemistry, 2021,Volume: 114
Authors:  Yang, Guan Jun;  Song, Ying Qi;  Wang, Wanhe;  Han, Quan Bin;  Ma, Dik Lung;  Leung, Chung Hang
Favorite |  | TC[WOS]:2 TC[Scopus]:1 | Submit date:2021/12/08
Acetylated RelA  BRD4  NF-κB  Protein-protein interaction  TNBC  
Drug screening strategies using metal-based luminescent probes Journal article
TrAC - Trends in Analytical Chemistry, 2021,Volume: 139
Authors:  Li, Guodong;  Wu, Chun;  Ma, Dik Lung;  Leung, Chung Hang
Favorite |  | TC[WOS]:0 TC[Scopus]:4 | Submit date:2021/12/08
Drug screening  Luminescence  Metal-based probes  
Ubiquitination Regulators Discovered by Virtual Screening for the Treatment of Cancer Journal article
Frontiers in Cell and Developmental Biology, 2021,Volume: 9
Authors:  Song, Ying Qi;  Wu, Chun;  Wu, Ke Jia;  Han, Quan Bin;  Miao, Xiang Min;  Ma, Dik Lung;  Leung, Chung Hang
Favorite |  | TC[WOS]:0 TC[Scopus]:0 | Submit date:2021/12/07
cancer  drug discovery  treatment  ubiquitination regulator  virtual screening  
The emerging role of KDM5A in human cancer Journal article
Journal of Hematology and Oncology, 2021,Volume: 14,Issue: 1
Authors:  Yang,Guan Jun;  Zhu,Ming Hui;  Lu,Xin Jiang;  Liu,Yan Jun;  Lu,Jian Fei;  Leung,Chung Hang;  Ma,Dik Lung;  Chen,Jiong
Favorite |  | TC[WOS]:4 TC[Scopus]:5 | Submit date:2021/03/01
Cancer  Drug Resistance  Histone Methylation  Jumonji c Domain  Kdm5a  Targeted Therapy  
Simultaneous blocking of the pan-RAF and S100B pathways as a synergistic therapeutic strategy against malignant melanoma Journal article
Journal of Cellular and Molecular Medicine, 2021,Volume: 25,Issue: 4,Page: 1972-1981
Authors:  Wu,Ke Jia;  Ho,Shih Hsin;  Wu,Chun;  Wang,Hui Min D.;  Ma,Dik Lung;  Leung,Chung Hang
Favorite |  | TC[WOS]:1 TC[Scopus]:2 | Submit date:2021/03/01
Drug Discovery  Malignant Melanoma  Pan-raf  S100b-p53 Interaction  Synergistic  
Time-resolved luminescent high-throughput screening platform for lysosomotropic compounds in living cells Journal article
ACS Sensors, 2020,Volume: 6,Issue: 1,Page: 166-174
Authors:  Wu,Ke Jia;  Wu,Chun;  Chen,Feng;  Cheng,Sha Sha;  Ma,Dik Lung;  Leung,Chung Hang
Favorite |  | TC[WOS]:3 TC[Scopus]:2 | Submit date:2021/03/01
High-throughput Screening  Iridium-based Ph Probe  Lysosomotropic Compounds  Mitoxantrone  Time-resolved Emission Spectroscopy