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Cisplatin prevents breast cancer metastasis through blocking early EMT and retards cancer growth together with paclitaxel Journal article
Theranostics, 2021,Volume: 11,Issue: 5,Page: 2442-2459
Authors:  Wang,Haitao;  Guo,Sen;  Kim,Seung Jin;  Shao,Fangyuan;  Kei Ho,Joshua Wing;  Wong,Kuan Un;  Miao,Zhengqiang;  Hao,Dapeng;  Zhao,Ming;  Xu,Jun;  Zeng,Jianming;  Wong,Koon Ho;  Di,Lijun;  Wong,Ada Hang Heng;  Xu,Xiaoling;  Deng,Chu Xia
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Cisplatin  Metastasis  Neoadjuvant Therapy  Paclitaxel  Tgfβ  
Characterization of BRCA1-deficient premalignant tissues and cancers identifies Plekha5 as a tumor metastasis suppressor Journal article
Nature Communications, 2020,Volume: 11,Issue: 1
Authors:  Liu,Jianlin;  Adhav,Ragini;  Miao,Kai;  Su,Sek Man;  Mo,Lihua;  Chan,Un In;  Zhang,Xin;  Xu,Jun;  Li,Jianjie;  Shu,Xiaodong;  Zeng,Jianming;  Zhang,Xu;  Lyu,Xueying;  Pardeshi,Lakhansing;  Tan,Kaeling;  Sun,Heng;  Wong,Koon Ho;  Deng,Chuxia;  Xu,Xiaoling
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NOTCH1 activation compensates BRCA1 deficiency and promotes triple-negative breast cancer formation Journal article
Nature Communications, 2020,Volume: 11,Issue: 1
Authors:  Miao,Kai;  Lei,Josh Haipeng;  Valecha,Monica Vishnu;  Zhang,Aiping;  Xu,Jun;  Wang,Lijian;  Lyu,Xueying;  Chen,Si;  Miao,Zhengqiang;  Zhang,Xin;  Su,Sek Man;  Shao,Fangyuan;  Rajendran,Barani Kumar;  Bao,Jiaolin;  Zeng,Jianming;  Sun,Heng;  Chen,Ping;  Tan,Kaeling;  Chen,Qiang;  Wong,Koon Ho;  Xu,Xiaoling;  Deng,Chu Xia
Favorite |  | TC[WOS]:5 TC[Scopus]:4 | Submit date:2020/09/16
A Three-Way Combinatorial CRISPR Screen for Analyzing Interactions among Druggable Targets Journal article
Cell Reports, 2020,Volume: 32,Issue: 6
Authors:  Zhou,Peng;  Chan,Becky K.C.;  Wan,Yuk Kei;  Yuen,Chaya T.L.;  Choi,Gigi C.G.;  Li,Xinran;  Tong,Cindy S.W.;  Zhong,Sophia S.W.;  Sun,Jieran;  Bao,Yufan;  Mak,Silvia Y.L.;  Chow,Maggie Z.Y.;  Khaw,Jien Vei;  Leung,Suet Yi;  Zheng,Zongli;  Cheung,Lydia W.T.;  Tan,Kaeling;  Wong,Koon Ho;  Chan,H. Y.Edwin;  Wong,Alan S.L.
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Cancer  Combigem  Combination Therapy  Combinatorial Genetics  Crispr  Drug Interaction  Genetic Interaction  High-throughput Screening  Neurodegeneration  Parkinson's Disease  
Deep-AmPEP30: Improve Short Antimicrobial Peptides Prediction with Deep Learning Journal article
Molecular Therapy - Nucleic Acids, 2020,Volume: 20,Page: 882-894
Authors:  Yan,Jielu;  Bhadra,Pratiti;  Li,Ang;  Sethiya,Pooja;  Qin,Longguang;  Tai,Hio Kuan;  Wong,Koon Ho;  Siu,Shirley W.I.
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AmPEP  ampicillin  antimicrobial peptide  AxPEP  Candida glabrata  convolutional neural network  drug discovery  machine learning  reduced amino acid composition  
Transcriptomic analysis reveals global and temporal transcription changes during Candida glabrata adaptation to an oxidative environment Journal article
Fungal Biology, 2020,Volume: 124,Issue: 5,Page: 427-439
Authors:  Sethiya,Pooja;  Rai,Maruti Nandan;  Rai,Rikky;  Parsania,Chirag;  Tan,Kaeling;  Wong,Koon Ho
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Oxidative Stress  Pathogenic Fungi  Transcriptome Profiling  
The Third International Symposium on Fungal Stress – ISFUS Journal article
Fungal Biology, 2020,Volume: 124,Issue: 5,Page: 235-252
Authors:  Alder-Rangel,Alene;  Idnurm,Alexander;  Brand,Alexandra C.;  Brown,Alistair J.P.;  Gorbushina,Anna;  Kelliher,Christina M.;  Campos,Claudia B.;  Levin,David E.;  Bell-Pedersen,Deborah;  Dadachova,Ekaterina;  Bauer,Florian F.;  Gadd,Geoffrey M.;  Braus,Gerhard H.;  Braga,Gilberto U.L.;  Brancini,Guilherme T.P.;  Walker,Graeme M.;  Druzhinina,Irina;  Pócsi,István;  Dijksterhuis,Jan;  Aguirre,Jesús;  Hallsworth,John E.;  Schumacher,Julia;  Wong,Koon Ho;  Selbmann,Laura;  Corrochano,Luis M.;  Kupiec,Martin;  Momany,Michelle;  Molin,Mikael;  Requena,Natalia;  Yarden,Oded;  Cordero,Radamés J.B.;  Fischer,Reinhard;  Pascon,Renata C.;  Mancinelli,Rocco L.;  Emri,Tamas;  Basso,Thiago O.;  Rangel,Drauzio E.N.
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Agricultural mycology  Fungal stress mechanisms and responses  Industrial mycology  Medical mycology  
Aspergillus fumigatus transcription factors involved in the caspofungin paradoxical effect Journal article
mBio, 2020,Volume: 11,Issue: 3,Page: 1-22
Authors:  Valero,Clara;  Colabardini,Ana Cristina;  Chiaratto,Jéssica;  Pardeshi,Lakhansing;  de Castro,Patrícia Alves;  Filho,Jaire Alves Ferreira;  Silva,Lilian Pereira;  Rocha,Marina Campos;  Malavazi,Iran;  Costa,Jonas Henrique;  Fill,Taícia;  Barros,Mário Henrique;  Wong,Sarah Sze Wah;  Aimanianda,Vishukumar;  Wong,Koon Ho;  Goldman,Gustavo H.
Favorite |  | TC[WOS]:0 TC[Scopus]:6 | Submit date:2021/03/04
Aspergillus fumigatus  Calcium  Caspofungin  Cell wall  Mitochondria  Transcription factors  
Adaptation to industrial stressors through genomic and transcriptional plasticity in a bioethanol producing fission yeast isolate Journal article
G3: Genes, Genomes, Genetics, 2020,Volume: 10,Issue: 4,Page: 1375-1391
Authors:  Vassiliadis,Dane;  Wong,Koon Ho;  Blinco,Jo;  Dumsday,Geoff;  Andrianopoulos,Alex;  Monahan,Brendon
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Adaptation  Bioethanol  Genomic  Plasticity  Pombe  Schizosaccharomyces  Transcriptional  
Exploration of gastric neuroendocrine carcinoma (GNEC) specific signaling pathways involved in chemoresistance via transcriptome and in vitro analysis Journal article
Computational and Structural Biotechnology Journal, 2020,Volume: 18,Page: 2610-2620
Authors:  Xie,Jianwei;  Chen,Pengchen;  Xie,Hongteng;  Sun,Yuqin;  Huang,Zhen;  Wei,Ran;  Miao,Zhengqiang;  Wang,Qingshui;  Zhang,Shu Dong;  Wong,Koon Ho;  Lin,Yao;  Huang,Changming;  Kwok,Hang Fai
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Chemoresistance  GAC  GNEC  NeuroD1  Transcriptome analysis