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Co-option of an extracellular protease for transcriptional control of nutrient degradation in the fungus Aspergillus nidulans Journal article
Communications Biology, 2021,Volume: 4,Issue: 1
Authors:  Li, Ang;  Parsania, Chirag;  Tan, Kaeling;  Todd, Richard B.;  Wong, Koon Ho
Favorite |  | TC[WOS]:0 TC[Scopus]:0 | Submit date:2022/01/14
Transcription in fungal conidia before dormancy produces phenotypically variable conidia that maximize survival in different environments Journal article
Nature Microbiology, 2021,Volume: 6,Issue: 8,Page: 1066-1081
Authors:  Wang, Fang;  Sethiya, Pooja;  Hu, Xiaohui;  Guo, Shuhui;  Chen, Yingying;  Li, Ang;  Tan, Kaeling;  Wong, Koon Ho
Favorite |  | TC[WOS]:3 TC[Scopus]:5 | Submit date:2021/12/08
Carbon catabolite repression in filamentous fungi is regulated by phosphorylation of the transcription factor crea Journal article
mBio, 2021,Volume: 12,Issue: 1,Page: 1-21
Authors:  de Assis, Leandro José;  Silva, Lilian Pereira;  Bayram, Ozgur;  Dowling, Paul;  Kniemeyer, Olaf;  Krüger, Thomas;  Brakhage, Axel A.;  Chen, Yingying;  Dong, Liguo;  Tan, Kaeling;  Wong, Koon Ho;  Ries, Laure N.A.;  Goldman, Gustavo H.
Favorite |  | TC[WOS]:6 TC[Scopus]:6 | Submit date:2021/12/07
Aspergillus Nidulans  Biofuels  Carbon Catabolite Repression  Crea  Xylanase  
Synthetic lethality of RB1 and aurora A is driven by stathmin-mediated disruption of microtubule dynamics Journal article
Nature Communications, 2020,Volume: 11,Issue: 1
Authors:  Lyu,Junfang;  Yang,Eun Ju;  Zhang,Baoyuan;  Wu,Changjie;  Pardeshi,Lakhansing;  Shi,Changxiang;  Mou,Pui Kei;  Liu,Yifan;  Tan,Kaeling;  Shim,Joong Sup
Favorite |  | TC[WOS]:6 TC[Scopus]:6 | Submit date:2021/03/04
NOTCH1 activation compensates BRCA1 deficiency and promotes triple-negative breast cancer formation Journal article
Nature Communications, 2020,Volume: 11,Issue: 1
Authors:  Miao,Kai;  Lei,Josh Haipeng;  Valecha,Monica Vishnu;  Zhang,Aiping;  Xu,Jun;  Wang,Lijian;  Lyu,Xueying;  Chen,Si;  Miao,Zhengqiang;  Zhang,Xin;  Su,Sek Man;  Shao,Fangyuan;  Rajendran,Barani Kumar;  Bao,Jiaolin;  Zeng,Jianming;  Sun,Heng;  Chen,Ping;  Tan,Kaeling;  Chen,Qiang;  Wong,Koon Ho;  Xu,Xiaoling;  Deng,Chu Xia
Favorite |  | TC[WOS]:15 TC[Scopus]:14 | Submit date:2020/09/16
Characterization of BRCA1-deficient premalignant tissues and cancers identifies Plekha5 as a tumor metastasis suppressor Journal article
Nature Communications, 2020,Volume: 11,Issue: 1
Authors:  Liu,Jianlin;  Adhav,Ragini;  Miao,Kai;  Su,Sek Man;  Mo,Lihua;  Chan,Un In;  Zhang,Xin;  Xu,Jun;  Li,Jianjie;  Shu,Xiaodong;  Zeng,Jianming;  Zhang,Xu;  Lyu,Xueying;  Pardeshi,Lakhansing;  Tan,Kaeling;  Sun,Heng;  Wong,Koon Ho;  Deng,Chuxia;  Xu,Xiaoling
Favorite |  | TC[WOS]:10 TC[Scopus]:10 | Submit date:2021/03/02
A Three-Way Combinatorial CRISPR Screen for Analyzing Interactions among Druggable Targets Journal article
Cell Reports, 2020,Volume: 32,Issue: 6
Authors:  Zhou,Peng;  Chan,Becky K.C.;  Wan,Yuk Kei;  Yuen,Chaya T.L.;  Choi,Gigi C.G.;  Li,Xinran;  Tong,Cindy S.W.;  Zhong,Sophia S.W.;  Sun,Jieran;  Bao,Yufan;  Mak,Silvia Y.L.;  Chow,Maggie Z.Y.;  Khaw,Jien Vei;  Leung,Suet Yi;  Zheng,Zongli;  Cheung,Lydia W.T.;  Tan,Kaeling;  Wong,Koon Ho;  Chan,H. Y.Edwin;  Wong,Alan S.L.
Favorite |  | TC[WOS]:4 TC[Scopus]:7 | Submit date:2021/03/04
Cancer  Combigem  Combination Therapy  Combinatorial Genetics  Crispr  Drug Interaction  Genetic Interaction  High-throughput Screening  Neurodegeneration  Parkinson's Disease  
The Aspergillus fumigatus transcription factor RglT is important for gliotoxin biosynthesis and self-protection, and virulence Journal article
PLoS Pathogens, 2020,Volume: 16,Issue: 7
Authors:  Ries,Laure N.A.;  Pardeshi,Lakhansing;  Dong,Zhiqiang;  Tan,Kaeling;  Steenwyk,Jacob L.;  Colabardini,Ana Cristina;  Filho,Jaire A.Ferreira;  De Castro,Patricia A.;  Silva,Lilian P.;  Preite,Nycolas W.;  Almeida,Fausto;  De Assis,Leandro J.;  Dos Santos,Renato A.C.;  Bowyer,Paul;  Bromley,Michael;  Owens,Rebecca A.;  Doyle,Sean;  Demasi,Marilene;  Hernández,Diego C.R.;  Netto,Luís Eduardo S.;  Pupo,Monica T.;  Rokas,Antonis;  Loures,Flavio V.;  Wong,Koon H.;  Goldman,Gustavo H.
Favorite |  | TC[WOS]:5 TC[Scopus]:5 | Submit date:2021/03/04
Transcriptomic analysis reveals global and temporal transcription changes during Candida glabrata adaptation to an oxidative environment Journal article
Fungal Biology, 2020,Volume: 124,Issue: 5,Page: 427-439
Authors:  Sethiya,Pooja;  Rai,Maruti Nandan;  Rai,Rikky;  Parsania,Chirag;  Tan,Kaeling;  Wong,Koon Ho
Favorite |  | TC[WOS]:5 TC[Scopus]:5 | Submit date:2021/03/04
Oxidative Stress  Pathogenic Fungi  Transcriptome Profiling  
Class I histone deacetylase inhibition is synthetic lethal with BRCA1 deficiency in breast cancer cells Journal article
Acta Pharmaceutica Sinica B, 2020,Volume: 10,Issue: 4,Page: 615-627
Authors:  Zhang,Baoyuan;  Lyu,Junfang;  Yang,Eun Ju;  Liu,Yifan;  Wu,Changjie;  Pardeshi,Lakhansing;  Tan,Kaeling;  Chen,Qiang;  Xu,Xiaoling;  Deng,Chu Xia;  Shim,Joong Sup
Favorite |  | TC[WOS]:14 TC[Scopus]:16 | Submit date:2020/09/16
Brca1  Breast Cancer  Dna Damage  Hdac  Histone Deacetylase  Reactive Oxygen Species  Synthetic Lethality