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Combination therapy with PD-1/PD-L1 blockade in non-small cell lung cancer: strategies and mechanisms Journal article
Pharmacology and Therapeutics, 2021,Volume: 219
Authors:  Huang,Mu Yang;  Jiang,Xiao Ming;  Wang,Bing Lin;  Sun,Yang;  Lu,Jin Jian
Favorite |  | TC[WOS]:5 TC[Scopus]:6 | Submit date:2021/03/02
Challenge  Combination Therapy  Immunotherapy  Mechanism  Nsclc  Pd-1/pd-l1  
Licochalcone A inhibits interferon-gamma-induced programmed death-ligand 1 in lung cancer cells Journal article
Phytomedicine, 2021,Volume: 80
Authors:  Yuan,Luo Wei;  Jiang,Xiao Ming;  Xu,Yu Lian;  Huang,Mu Yang;  Chen,Yu Chi;  Yu,Wei Bang;  Su,Min Xia;  Ye,Zi Han;  Chen,Xiuping;  Wang,Yitao;  Lu,Jin Jian
Favorite |  | TC[WOS]:1 TC[Scopus]:2 | Submit date:2021/03/01
Ifn-γ  Licochalcone a  Natural Products  Pd-l1  Protein Synthesis Inhibitor  Ros  
TGFβ2-mediated epithelial–mesenchymal transition and NF-κB pathway activation contribute to osimertinib resistance Journal article
Acta Pharmacologica Sinica, 2020,Volume: 42,Issue: 3,Page: 451-459
Authors:  Jiang,Xiao ming;  Xu,Yu lian;  Yuan,Luo wei;  Zhang,Le le;  Huang,Mu yang;  Ye,Zi han;  Su,Min xia;  Chen,Xiu ping;  Zhu,Hong;  Ye,Richard D.;  Lu,Jin jian
Favorite |  | TC[WOS]:4 TC[Scopus]:3 | Submit date:2021/03/01
Egfr Mutant Non-small Cell Lung Cancer  Epithelial-mesenchymal Transition  Nf-κb  Osimertinib Resistance  Tgfβ2  
Nagilactone E increases PD-L1 expression through activation of c-Jun in lung cancer cells Journal article
Chinese Journal of Natural Medicines, 2020,Volume: 18,Issue: 7,Page: 517-525
Authors:  CHEN,Yu Chi;  HUANG,Mu Yang;  ZHANG,Le Le;  FENG,Zhe Ling;  JIANG,Xiao Ming;  YUAN,Luo Wei;  HUANG,Run Yue;  LIU,Bo;  YU,Hua;  WANG,Yi Tao;  CHEN,Xiu Ping;  LIN,Li Gen;  LU,Jin Jian
Favorite |  | TC[WOS]:4 TC[Scopus]:5 | Submit date:2021/03/01
C-jun  Jnk  Lung Cancer  Nagilactone e  Programmed Death Ligand 1  
Phanginin R induces cytoprotective autophagy via JNK/C-JUN signaling pathway in non-small cell lung cancer A549 cells Journal article
Anti-Cancer Agents in Medicinal Chemistry, 2020,Volume: 20,Issue: 8,Page: 982-988
Authors:  Zhang,Le Le;  Bao,Han;  Xu,Yu Lian;  Jiang,Xiao Ming;  Li,Wei;  Zou,Liang;  Lin,Li Gen;  Lu,Jin Jian
Favorite |  | TC[WOS]:1 TC[Scopus]:2 | Submit date:2021/03/01
Anti-cancer  Autophagy  C-jun  Jnk  Non-small Cell Lung Cancer  Phanginin r  
Activation of notch 3/c-MYC/CHOP axis regulates apoptosis and promotes sensitivity of lung cancer cells to mTOR inhibitor everolimus Journal article
Biochemical Pharmacology, 2020,Volume: 175
Authors:  Li,Ting;  Xu,Xiao Huang;  Guo,Xia;  Yuan,Tao;  Tang,Zheng Hai;  Jiang,Xiao Ming;  Xu,Yu Lian;  Zhang,Le Le;  Chen,Xiuping;  Zhu,Hong;  Shi,Jia Jie;  Lu,Jin Jian
Favorite |  | TC[WOS]:4 TC[Scopus]:4 | Submit date:2021/03/01
Apoptosis  C-myc  Chop  Lung Cancer  Notch 3  
Identification of nagilactone E as a protein synthesis inhibitor with anticancer activity Journal article
Acta Pharmacologica Sinica, 2020,Volume: 41,Issue: 5,Page: 698-705
Authors:  Zhang,Le le;  Guo,Jing;  Jiang,Xiao ming;  Chen,Xiu ping;  Wang,Yi tao;  Li,Ao;  Lin,Li gen;  Li,Hua;  Lu,Jin jian
Favorite |  | TC[WOS]:11 TC[Scopus]:11 | Submit date:2021/03/01
Click-it  Cmap  Diterpenoids  Human Lung Cancer A549 Cell Line Xenograft  Molecular Docking  Nagilactone e  Protein Synthesis Inhibitor  Riok2  Rna-seq  
Establishment and characterization of pemetrexed-resistant NCI-H460/PMT cells Journal article
Anti-Cancer Agents in Medicinal Chemistry, 2019,Volume: 19,Issue: 6,Page: 731-739
Authors:  Xu,Yu Lian;  Jiang,Xiao Ming;  Zhang,Le Le;  Chen,Xiuping;  Huang,Zhang Jian;  Lu,Jin Jian
Favorite |  | TC[WOS]:2 TC[Scopus]:2 | Submit date:2021/03/01
Abcb1  Chemotherapy  Nsclc  Pemetrexed  Resistance  Tyms  
Small molecule IVQ, as a prodrug of gluconeogenesis inhibitor QVO, efficiently ameliorates glucose homeostasis in type 2 diabetic mice Journal article
ACTA PHARMACOLOGICA SINICA, 2019,Volume: 40,Issue: 9,Page: 1193-1204
Authors:  Ting-ting Zhou;  Tong Zhao;  Fei Ma;  Yi-nan Zhang;  Jing Jiang;  Yuan Ruan;  Qiu-ying Yan;  Gai-hong Wang;  Jin Ren;  Xiao-wei Guan;  Jun Guo;  Yong-hua Zhao;  Ji-ming Ye;  Li-hong Hu;  Jing Chen;  Xu Shen
Favorite |  | TC[WOS]:3 TC[Scopus]:3 | Submit date:2020/04/14
Type 2 Diabetes Mellitus  Hepatic Gluconeogenesis  Ampk Signaling Pathway  (e)-3-(2-(Quinoline-4-yl)Vinyl)-1h-indol-6-ol (Qvo)  4-[2-(1h-indol-3-yl)Vinyl]Quinoline (Ivq)  Prodrug  
Resequencing 545 ginkgo genomes across the world reveals the evolutionary history of the living fossil Journal article
NATURE COMMUNICATIONS, 2019,Volume: 10
Authors:  Yun-Peng Zhao;  Guangyi Fan;  Ping-Ping Yin;  Shuai Sun;  Ning Li;  Xiaoning Hong;  Gang Hu;  He Zhang;  Fu-Min Zhang;  Jing-Dan Han;  Ya-Jun Hao;  Qiwu Xu;  Xianwei Yang;  Wenjie Xia;  Wenbin Chen;  Han-Yang Lin;  Rui Zhang;  Jiang Chen;  Xiao-Ming Zheng;  Simon Ming-Yuen Lee;  Joongku Lee;  Koichi Uehara;  Jian Wang;  Huanming Yang;  Cheng-Xin Fu;  Xin Liu;  Xun Xu;  Song Ge
Favorite |  | TC[WOS]:23 TC[Scopus]:28 | Submit date:2020/01/16