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BHDPC is a novel neuroprotectant that provides anti-neuroinflammatory and neuroprotective effects by inactivating NF-κB and activating PKA/CREB Journal article
Frontiers in Pharmacology, 2018,Volume: 9,Issue: JUN
Authors:  Li C.;  Chen T.;  Zhou H.;  Feng Y.;  Hoi M.P.M.;  Ma D.;  Zhao C.;  Zheng Y.;  Lee S.M.Y.
Favorite |  | TC[WOS]:8 TC[Scopus]:9 | Submit date:2018/11/06
BHDPC  CREB  Microglia  Neuroinflammation  NF-κB  PKA  
Inhibitory effects of betulinic acid on LPS-induced neuroinflammation involve M2 microglial polarization via CaMKKβ-dependent AMPK activation Journal article
Frontiers in Molecular Neuroscience, 2018,Volume: 11
Authors:  Li C.;  Zhang C.;  Zhou H.;  Feng Y.;  Tang F.;  Hoi M.P.M.;  He C.;  Ma D.;  Zhao C.;  Lee S.M.Y.
Favorite |  | TC[WOS]:33 TC[Scopus]:33 | Submit date:2018/11/06
AMP-activated protein kinase  Betulinic acid  Calmodulin-dependent protein kinase β  Microglia polarization  Neuroinflammation  
Tanshinone I prevents atorvastatin-induced cerebral hemorrhage in zebrafish and stabilizes endothelial cell–cell adhesion by inhibiting VE-cadherin internalization and actin-myosin contractility Journal article
Pharmacological Research, 2018,Volume: 128,Page: 389-398
Authors:  Huang B.;  Zhou Z.-Y.;  Li S.;  Huang X.-H.;  Tang J.-Y.;  Hoi M.P.M.;  Lee S.M.Y.
Favorite |  | TC[WOS]:10 TC[Scopus]:11 | Submit date:2018/11/06
Endothelial cell adhesion  Hemorrhagic stroke  HUVECs  Tanshinone I  Vascular integrity  Zebrafish  
Calycosin and Formononetin Induce Endothelium-Dependent Vasodilation by the Activation of Large-Conductance Ca2+-Activated K+ Channels (BKCa) Journal article
Evidence-based Complementary and Alternative Medicine, 2016,Volume: 2016
Authors:  Tseng H.H.L.;  Vong C.T.;  Leung G.P.-H.;  Seto S.W.;  Kwan Y.W.;  Lee S.M.-Y.;  Hoi M.P.M.
Favorite |  | TC[WOS]:1 TC[Scopus]:6 | Submit date:2018/11/06
Relaxation effect of a novel Danshensu/tetramethylpyrazine derivative on rat mesenteric arteries Journal article
European Journal of Pharmacology, 2015,Volume: 761,Page: 153-160
Authors:  Li R.W.-S.;  Yang C.;  Shan L.;  Zhang Z.;  Wang Y.;  Kwan Y.W.;  Lee S.M.Y.;  Hoi M.P.M.;  Chan S.W.;  Cheung A.C.;  Cheung K.H.;  Leung G.P.H.
Favorite |  | TC[WOS]:13 TC[Scopus]:13 | Submit date:2018/11/06
Calcium Channel  Danshensu Tetramethylpyrazine  Mesenteric Artery  Relaxation  
Basal Flt1 tyrosine kinase activity is a positive regulator of endothelial survival and vascularization during zebrafish embryogenesis Journal article
Biochimica et Biophysica Acta - General Subjects, 2015,Volume: 1850,Issue: 2,Page: 373-384
Authors:  Li S.;  Zhou X.L.;  Dang Y.Y.;  Kwan Y.W.;  Chan S.W.;  Leung G.P.H.;  Lee S.M.-Y.;  Hoi M.P.M.
Favorite |  | TC[WOS]:9 TC[Scopus]:11 | Submit date:2018/11/06
Calycosin  Endothelial Cell  Flt1  Molecular Docking  Vegf Receptor Inhibitor  Zebrafish  
VEGFR tyrosine kinase inhibitor II (VRI) induced vascular insufficiency in zebrafish as a model for studying vascular toxicity and vascular preservation Journal article
Toxicology and Applied Pharmacology, 2014,Volume: 280,Issue: 3,Page: 408-420
Authors:  Li S.;  Dang Y.Y.;  Oi Lam Che G.;  Kwan Y.W.;  Chan S.W.;  Leung G.P.H.;  Lee S.M.Y.;  Hoi M.P.M.
Favorite |  | TC[WOS]:30 TC[Scopus]:30 | Submit date:2018/11/06
Cardiovascular Protective Agents  Cardiovascular Toxicity  Vascular Insufficiency  Zebrafish Model  
Uptake and protective effects of ergothioneine in human endothelial cells Journal article
Journal of Pharmacology and Experimental Therapeutics, 2014,Volume: 350,Issue: 3,Page: 691-700
Authors:  Li R.W.S.;  Yang C.;  Sit A.S.M.;  Kwan Y.W.;  Lee S.M.Y.;  Hoi M.P.M.;  Chan S.W.;  Hausman M.;  Vanhoutte P.M.;  Leung G.P.H.
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Acute Simvastatin Inhibits KATP Channels of Porcine Coronary Artery Myocytes Journal article
PLoS ONE, 2013,Volume: 8,Issue: 6
Authors:  Seto S.W.;  Au A.L.S.;  Poon C.C.W.;  Zhang Q.;  Li R.W.S.;  Yeung J.H.K.;  Kong S.K.;  Ngai S.M.;  Wan S.;  Ho H.P.;  Lee S.M.Y.;  Hoi M.P.M.;  Chan S.W.;  Leung G.P.H.;  Kwan Y.W.
Favorite |  | TC[WOS]:11 TC[Scopus]:12 | Submit date:2018/10/30
Baicalein protects against 6-OHDA-induced neurotoxicity through activation of Keap1/Nrf2/HO-1 and involving PKCα and PI3K/AKT signaling pathways Journal article
Journal of Agricultural and Food Chemistry, 2012,Volume: 60,Issue: 33,Page: 8171
Authors:  Zhang Z.;  Cui W.;  Li G.;  Yuan S.;  Xu D.;  Hoi M.P.M.;  Lin Z.;  Dou J.;  Han Y.;  Lee S.M.Y.
Favorite |  | TC[WOS]:121 TC[Scopus]:127 | Submit date:2018/10/30