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Oral pharmacokinetics of baicalin, wogonoside, oroxylin A 7-O-β-D-glucuronide and their aglycones from an aqueous extract of Scutellariae Radix in the rat Journal article
Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences, 2015,Volume: 1026,Page: 124
Authors:  Cai Y.;  Li S.;  Li T.;  Zhou R.;  Yan R.;  Wai A.T.-S.
Favorite |  | TC[WOS]:25 TC[Scopus]:28 | Submit date:2018/10/30
Hepatic Glucuronidation  Intestinal Permeability  Isomerization  Microbial Metabolism  Scutellaria Radix  Systemic Exposure  
Regioselective glucuronidation of the isoflavone calycosin by human liver microsomes and recombinant human UDP-glucuronosyltransferases Journal article
Chemico-Biological Interactions, 2014,Volume: 220,Page: 231-240
Authors:  Ruan J.-Q.;  Yan R.
Favorite |  | TC[WOS]:14 TC[Scopus]:15 | Submit date:2018/12/28
Calycosin  Glucuronidation  Metabolism  Regioselectivity  Udp-glucuronosyltransferases  
In vitro glucuronidation of five rhubarb anthraquinones by intestinal and liver microsomes from humans and rats Journal article
Chemico-Biological Interactions, 2014,Volume: 219,Page: 18-27
Authors:  Wu W.;  Hu N.;  Zhang Q.;  Li Y.;  Li P.;  Yan R.;  Wang Y.
Favorite |  | TC[WOS]:39 TC[Scopus]:36 | Submit date:2018/10/31
Anthraquinones  Glucuronidation  Regioselectivity  Rhubarb  Ugts  
Regioselective glucuronidation of oxyresveratrol, a natural hydroxystilbene, by human liver and intestinal microsomes and recombinant ugts Journal article
Drug Metabolism and Pharmacokinetics, 2014,Volume: 29,Issue: 3,Page: 229
Authors:  Hu N.;  Mei M.;  Ruan J.;  Wu W.;  Wang Y.;  Yan R.
Favorite |  | TC[WOS]:5 TC[Scopus]:5 | Submit date:2018/10/31
Glucuronidation  Kinetics  Oxyresveratrol  Oxyresveratrol-2-o-β-d-glucuronosyl  Regioselectivity  Ugt1a9  Uridine Diphospho-glucuronosyltransferase (Ugts)  
In vitro pharmacokinetic characterization of mulberroside A, the main polyhydroxylated stilbene in mulberry (Morus alba L.), and its bacterial metabolite oxyresveratrol in traditional oral use Journal article
Journal of Agricultural and Food Chemistry, 2012,Volume: 60,Issue: 9,Page: 2299
Authors:  Mei M.;  Ruan J.-Q.;  Wu W.-J.;  Zhou R.-N.;  Lei P.-C.;  Zhao H.-Y.;  Yan R.;  Wang Y.-T.
Favorite |  | TC[WOS]:31 TC[Scopus]:35 | Submit date:2018/10/30
Deglycosylation  Glucuronidation  Hydroxystilbenes  Intestinal Bacteria  Morus AL.a L.  Mulberroside a  Oxyresveratrol  Permeability  
Intestinal transport of scutellarein and scutellarin and first-pass metabolism by UDP-glucuronosyltransferase-mediated glucuronidation of scutellarein and hydrolysis of scutellarin Journal article
Xenobiotica, 2011,Volume: 41,Issue: 7,Page: 538-548
Authors:  Yazhi Wang;  Heisio Ao;  Zhengming Qian;  Ying Zheng
Favorite |  | TC[WOS]:18 TC[Scopus]:20 | Submit date:2020/04/09
Udp-glucuronosyltransferase  Scutellarein (s)  Scutellarin (Sg)  Caco-2 Cell Monolayer  Glucuronidation