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Cisplatin prevents breast cancer metastasis through blocking early EMT and retards cancer growth together with paclitaxel Journal article
Theranostics, 2021,Volume: 11,Issue: 5,Page: 2442-2459
Authors:  Wang,Haitao;  Guo,Sen;  Kim,Seung Jin;  Shao,Fangyuan;  Kei Ho,Joshua Wing;  Wong,Kuan Un;  Miao,Zhengqiang;  Hao,Dapeng;  Zhao,Ming;  Xu,Jun;  Zeng,Jianming;  Wong,Koon Ho;  Di,Lijun;  Wong,Ada Hang Heng;  Xu,Xiaoling;  Deng,Chu Xia
Favorite |  | TC[WOS]:3 TC[Scopus]:3 | Submit date:2021/03/02
Cisplatin  Metastasis  Neoadjuvant Therapy  Paclitaxel  Tgfβ  
Accelerating precision anti-cancer therapy by time-lapse and label-free 3D tumor slice culture platform Journal article
Theranostics, 2021,Volume: 11,Issue: 19,Page: 9415-9430
Authors:  Xing, Fuqiang;  Liu, Yu Cheng;  Huang, Shigao;  Lyu, Xueying;  Su, Sek Man;  Chan, Un In;  Wu, Pei Chun;  Yan, Yinghan;  Ai, Nana;  Li, Jianjie;  Zhao, Ming;  Rajendran, Barani Kumar;  Liu, Jianlin;  Shao, Fangyuan;  Sun, Heng;  Choi, Tak Kan;  Zhu, Wenli;  Luo, Guanghui;  Liu, Shuiming;  Xu, De Li;  Chan, Kin Long;  Zhao, Qi;  Miao, Kai;  Luo, Kathy Qian;  Ge, Wei;  Xu, Xiaoling;  Wang, Guanyu;  Liu, Tzu Ming;  Deng, Chu Xia
Favorite |  | TC[WOS]:0 TC[Scopus]:0 | Submit date:2021/11/30
3D tumor slice culture  Apoptosis  FRET technique  Label-free  Personalized medicine  
Enhanced Protein Damage Clearance Induces Broad Drug Resistance in Multitype of Cancers Revealed by an Evolution Drug-Resistant Model and Genome-Wide siRNA Screening Journal article
Advanced Science, 2020,Volume: 7,Issue: 23
Authors:  Shao,Fangyuan;  Lyu,Xueying;  Miao,Kai;  Xie,Lisi;  Wang,Haitao;  Xiao,Hao;  Li,Jie;  Chen,Qiang;  Ding,Renbo;  Chen,Ping;  Xing,Fuqiang;  Zhang,Xu;  Luo,Guang Hui;  Zhu,Wenli;  Cheng,Gregory;  Lon,Ng Wai;  Martin,Scott E.;  Wang,Guanyu;  Chen,Guokai;  Dai,Yunlu;  Deng,Chu Xia
Favorite |  | TC[WOS]:3 TC[Scopus]:3 | Submit date:2021/03/02
Broad Drug Resistance  Caspase 3 Activation  Patient-derived Organoid  Proteolysis  Rnai Screening  
NOTCH1 activation compensates BRCA1 deficiency and promotes triple-negative breast cancer formation Journal article
Nature Communications, 2020,Volume: 11,Issue: 1
Authors:  Miao,Kai;  Lei,Josh Haipeng;  Valecha,Monica Vishnu;  Zhang,Aiping;  Xu,Jun;  Wang,Lijian;  Lyu,Xueying;  Chen,Si;  Miao,Zhengqiang;  Zhang,Xin;  Su,Sek Man;  Shao,Fangyuan;  Rajendran,Barani Kumar;  Bao,Jiaolin;  Zeng,Jianming;  Sun,Heng;  Chen,Ping;  Tan,Kaeling;  Chen,Qiang;  Wong,Koon Ho;  Xu,Xiaoling;  Deng,Chu Xia
Favorite |  | TC[WOS]:11 TC[Scopus]:11 | Submit date:2020/09/16
Arginine accelerates intestinal health through cytokines and intestinal microbiota Journal article
International Immunopharmacology, 2020,Volume: 81
Authors:  Wu, Miaomiao;  Xiao, Hao;  Shao, Fangyuan;  Tan, Bie;  Hu, Shenglan
Favorite |  | TC[WOS]:4 TC[Scopus]:5 | Submit date:2021/12/06
Arginine  Intestinal immunity  Intestinal microbiota  Secretory immunoglobulin A  T cells  
Amino acids regulate energy utilization through mammalian target of rapamycin complex 1 and adenosine monophosphate activated protein kinase pathway in porcine enterocytes Journal article
Animal Nutrition, 2020,Volume: 6,Issue: 1,Page: 98-106
Authors:  Xiao, Hao;  Zha, Cuifang;  Shao, Fangyuan;  Wang, Li;  Tan, Bi'e
Favorite |  | TC[WOS]:1 TC[Scopus]:2 | Submit date:2021/12/06
Adenosine monophosphate activated protein kinase  Amino acids  Energy utilization  Mammalian target of rapamycin  Mitochondrial respiration  
BRCA1 represses DNA replication initiation through antagonizing estrogen signaling and maintains genome stability in parallel with WEE1-MCM2 signaling during pregnancy Journal article
Human molecular genetics, 2018
Authors:  Xiaoling Xu;  Eric Chen;  Lihua Mo;  Lei Zhang;  Fangyuan Shao;  Kai Miao;  Jianlin Liu;  Sek Man Su;  Monica Valecha;  Un In Chan;  Hongping Zheng;  Mark Chen;  Weiping Chen;  Qiang Chen;  Haiqing Fu;  Mirit I. Aladjem;  Yanzhen He;  Chu-Xia Deng
Favorite |  | TC[WOS]:6 TC[Scopus]:5 | Submit date:2018/12/17
Potential therapeutic targets of triple-negative breast cancer based on its intrinsic subtype Journal article
ONCOTARGET, 2017,Volume: 8,Issue: 42,Page: 73329-73344
Authors:  Shao, Fangyuan;  Sun, Heng;  Deng, Chu-Xia
Favorite |  | TC[WOS]:41 TC[Scopus]:40 | Submit date:2018/10/30
Cancer Therapy  Tnbc Subtype  Cscs  Drug Resistance  Cancer Targets  
The role of nitric oxide pathway in arginine transport and growth of IPEC-1 cells Journal article
ONCOTARGET, 2017,Volume: 8,Issue: 18,Page: 29976-29983
Authors:  Xiao, Hao;  Zeng, Liming;  Shao, Fangyuan;  Huang, Bo;  Wu, Miaomiao;  Tan, Bie;  Yin, Yulong
Favorite |  | TC[WOS]:7 TC[Scopus]:7 | Submit date:2018/10/30
arginine  nitric oxide synthase  mTOR  intestinal porcine epithelial cells (IPEC)  
WEE1 inhibition targets cell cycle checkpoints for triple negative breast cancers to overcome cisplatin resistance Journal article
SCIENTIFIC REPORTS, 2017,Volume: 7
Authors:  Zheng, Hongping;  Shao, Fangyuan;  Martin, Scots;  Xu, Xiaoling;  Deng, Chu-Xia
Favorite |  | TC[WOS]:33 TC[Scopus]:33 | Submit date:2018/10/30