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Activation of FGFR2 Signaling Suppresses BRCA1 and Drives Triple-Negative Mammary Tumorigenesis That is Sensitive to Immunotherapy Journal article
Advanced Science, 2021,Volume: 8,Issue: 21
Authors:  Lei, Josh Haipeng;  Lee, Mi Hye;  Miao, Kai;  Huang, Zebin;  Yao, Zhicheng;  Zhang, Aiping;  Xu, Jun;  Zhao, Ming;  Huang, Zenan;  Zhang, Xin;  Chen, Si;  Jiaying, N. G.;  Feng, Yuzhao;  Xing, Fuqiang;  Chen, Ping;  Sun, Heng;  Chen, Qiang;  Xiang, Tingxiu;  Chen, Lin;  Xu, Xiaoling;  Deng, Chu Xia
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Brca1  Breast Cancer  Fgfr2 Inhibitor  Fgfr2-s252w  Tumor Slice Culture  
Sirt1 deficiency upregulates glutathione metabolism to prevent hepatocellular carcinoma initiation in mice Journal article
Oncogene, 2021,Volume: 40,Issue: 41,Page: 6023-6033
Authors:  Qiu, Pengxiang;  Hou, Weilong;  Wang, Haitao;  Lei, Kimmy Ka Wing;  Wang, Shaowei;  Chen, Weiping;  Pardeshi, Lakhansing Arun;  Prothro, Katherine;  Shukla, Yashvita;  Su, Samson Sek Man;  Schrump, David S.;  Chen, Qiang;  Deng, Chu Xia;  Xu, Xiaoling;  Wang, Ruihong
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Cancer cells escape p53’s tumor suppression through ablation of ZDHHC1-mediated p53 palmitoylation Journal article
Oncogene, 2021,Volume: 40,Issue: 35,Page: 5416-5426
Authors:  Tang, Jun;  Peng, Weiyan;  Feng, Yixiao;  Le, Xin;  Wang, Kang;  Xiang, Qin;  Li, Lili;  Wang, Yan;  Xu, Can;  Mu, Junhao;  Xu, Ke;  Ji, Ping;  Tao, Qian;  Huang, Ailong;  Deng, Chu Xia;  Lin, Yong;  Xiang, Tingxiu
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Expansion of Rare Cancer Cells into Tumoroids for Therapeutic Regimen and Cancer Therapy Journal article
Advanced Therapeutics, 2021,Volume: 4,Issue: 7
Authors:  Enkhbat, Myagmartsend;  Liu, Yung Chiang;  Kim, Jua;  Xu, Yanshan;  Yin, Zongyi;  Liu, Tzu Ming;  Deng, Chu Xia;  Zou, Chang;  Xie, Xi;  Li, Xiaowu;  Wang, Peng Yuan
Favorite |  | TC[WOS]:1 TC[Scopus]:1 | Submit date:2021/12/08
assembloid  cancer stem cell  circulating tumor cell  drug screening  microenvironment  
SRC-3, a steroid receptor coactivator: Implication in cancer Journal article
International Journal of Molecular Sciences, 2021,Volume: 22,Issue: 9
Authors:  Li, Licen;  Deng, Chu Xia;  Chen, Qiang
Favorite |  | TC[WOS]:1 TC[Scopus]:1 | Submit date:2021/12/07
AIB1  Cancer  Coactivator  SRC-3  
Molecular landscape and subtype-specific therapeutic response of nasopharyngeal carcinoma revealed by integrative pharmacogenomics Journal article
Nature Communications, 2021,Volume: 12,Issue: 1
Authors:  Ding, Ren Bo;  Chen, Ping;  Rajendran, Barani Kumar;  Lyu, Xueying;  Wang, Haitao;  Bao, Jiaolin;  Zeng, Jianming;  Hao, Wenhui;  Sun, Heng;  Wong, Ada Hang Heng;  Valecha, Monica Vishnu;  Yang, Eun Ju;  Su, Sek Man;  Choi, Tak Kan;  Liu, Shuiming;  Chan, Kin Iong;  Yang, Ling Lin;  Wu, Jingbo;  Miao, Kai;  Chen, Qiang;  Shim, Joong Sup;  Xu, Xiaoling;  Deng, Chu Xia
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Function of DHX33 in promoting Warburg effect via regulation of glycolytic genes Journal article
Journal of Cellular Physiology, 2021,Volume: 236,Issue: 2,Page: 981-996
Authors:  Peng,Cheng;  Hou,Sheng Tao;  Deng,Chu Xia;  Zhang,Yandong
Favorite |  | TC[WOS]:1 TC[Scopus]:0 | Submit date:2021/03/02
Demethylation  Dhx33  Gadd45a  Glycolysis  Rna Helicase  Warburg Effect  
Accelerating precision anti-cancer therapy by time-lapse and label-free 3D tumor slice culture platform Journal article
Theranostics, 2021,Volume: 11,Issue: 19,Page: 9415-9430
Authors:  Xing, Fuqiang;  Liu, Yu Cheng;  Huang, Shigao;  Lyu, Xueying;  Su, Sek Man;  Chan, Un In;  Wu, Pei Chun;  Yan, Yinghan;  Ai, Nana;  Li, Jianjie;  Zhao, Ming;  Rajendran, Barani Kumar;  Liu, Jianlin;  Shao, Fangyuan;  Sun, Heng;  Choi, Tak Kan;  Zhu, Wenli;  Luo, Guanghui;  Liu, Shuiming;  Xu, De Li;  Chan, Kin Long;  Zhao, Qi;  Miao, Kai;  Luo, Kathy Qian;  Ge, Wei;  Xu, Xiaoling;  Wang, Guanyu;  Liu, Tzu Ming;  Deng, Chu Xia
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3D tumor slice culture  Apoptosis  FRET technique  Label-free  Personalized medicine  
Dissecting the heterogeneity and tumorigenesis of BRCA1 deficient mammary tumors via single cell RNA sequencing Journal article
Theranostics, 2021,Volume: 11,Issue: 20,Page: 9967-9987
Authors:  Sun, Heng;  Zeng, Jianming;  Miao, Zhengqiang;  Lei, Kuan Cheok;  Huang, Chen;  Hu, Lingling;  Su, Sek Man;  Chan, Un In;  Miao, Kai;  Zhang, Xu;  Zhang, Aiping;  Guo, Sen;  Chen, Si;  Meng, Ya;  Deng, Min;  Hao, Wenhui;  Lei, Haipeng;  Lin, Ying;  Yang, Zhonglin;  Tang, Dongjiang;  Wong, Koon Ho;  Zhang, Xiaohua Douglas;  Xu, Xiaoling;  Deng, Chu Xia
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Brca1/BRCA1  Mammary tumor  Mrc2  Single cell RNA-seq  Tumor heterogeneity  
Upregulation of amplified in breast cancer 1 contributes to pancreatic ductal adenocarcinoma progression and vulnerability to blockage of hedgehog activation Journal article
Theranostics, 2021,Volume: 11,Issue: 4,Page: 1672-1689
Authors:  Li,Licen;  Bao,Jiaolin;  Wang,Haitao;  Lei,Josh Haipeng;  Peng,Cheng;  Zeng,Jianming;  Hao,Wenhui;  Zhang,Xu;  Xu,Xiaoling;  Yu,Chundong;  Deng,Chu Xia;  Chen,Qiang
Favorite |  | TC[WOS]:1 TC[Scopus]:1 | Submit date:2021/03/02
Aib1  Ecm  Hedgehog  Mafb  Pdac