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Using Acetone/Water Binary Solvent to Enhance the Stability and Bioavailability of Spray Dried Enzalutamide/HPMC-AS Solid Dispersions Journal article
Journal of Pharmaceutical Sciences, 2021,Volume: 110,Issue: 3,Page: 1160-1171
Authors:  Zhang,Xiaoting;  Rao,Qiuhong;  Qiu,Zhenwen;  Lin,Yisheng;  Zhang,Lei;  Hu,Qingzhong;  Chen,Tingting;  Ma,Zhimin;  Gao,Hanlu;  Luo,Dandong;  Zhao,Jiaqi;  Ouyang,Defang;  Zhang,Zhenyu Jason;  Li,Qingguo
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Amorphous Solid Dispersion  Drug-excipient Interaction  Particle Size  Poorly Water-soluble Drug  Spray Drying  
Development of a Highly Water-Soluble Lycopene Cyclodextrin Ternary Formulation by the Integrated Experimental and Modeling Techniques Journal article
AAPS PharmSciTech, 2021,Volume: 22,Issue: 1
Authors:  Ma,Yan;  Zhong,Liuting;  Peng,Zhuo;  Liu,Xinyang;  Ouyang,Defang;  Guan,Shixia
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Bioavailability  Hot-melt Extrusion  Lycopene  Molecular Dynamics Simulation  Ternary Formulation  
Integrated computer-aided formulation design: A case study of andrographolide/ cyclodextrin ternary formulation Journal article
Asian Journal of Pharmaceutical Sciences, 2021,Volume: 16,Issue: 4,Page: 494-507
Authors:  Gao, Haoshi;  Su, Yan;  Wang, Wei;  Xiong, Wei;  Sun, Xiyang;  Ji, Yuanhui;  Yu, Hua;  Li, Haifeng;  Ouyang, Defang
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Andrographolide  Cyclodextrins  Integrated Computer-aided Formulation Design  Machine Learning  Molecular Dynamic Simulation  Physiologically Based Absorption Modeling  
An integrated computational methodology with data-driven machine learning, molecular modeling and PBPK modeling to accelerate solid dispersion formulation design Journal article
European Journal of Pharmaceutics and Biopharmaceutics, 2021,Volume: 158,Page: 336-346
Authors:  Gao,Hanlu;  Wang,Wei;  Dong,Jie;  Ye,Zhuyifan;  Ouyang,Defang
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Dissolution Profile  Machine Learning  Molecular Dynamics (Md) Simulations  Pharmacokinetic Modeling  Solid Dispersion  
Integrated in silico formulation design of self-emulsifying drug delivery systems Journal article
Acta Pharmaceutica Sinica B, 2021
Authors:  Gao, Haoshi;  Jia, Haoyue;  Dong, Jie;  Yang, Xinggang;  Li, Haifeng;  Ouyang, Defang
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Central composite design  Meloxicam  Molecular dynamic simulation  Random forest  Self-emulsifying drug delivery system  
Food bioactive small molecule databases: Deep boosting for the study of food molecular behaviors Journal article
Innovative Food Science and Emerging Technologies, 2020,Volume: 66
Authors:  Yang,Zheng Fei;  Xiao,Ran;  Luo,Fei Jun;  Lin,Qin Lu;  Ouyang,Defang;  Dong,Jie;  Zeng,Wen Bin
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Bioactive Data  Food  Food Compound  Food Database  Small Molecule  
The pharmacological activity of epigallocatechin-3-gallate (EGCG) on Alzheimer's disease animal model: A systematic review Journal article
Phytomedicine, 2020,Volume: 79
Authors:  Zhang,Shuang;  Zhu,Qi;  Chen,Jia Yue;  OuYang,Defang;  Lu,Jia Hong
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Ad Animal Models  Alzheimer's Disease  Clinical Trials  Egcg  Neuroprotective Effects  Systematic Review  
Small Molecular Prodrug Amphiphile Self-Assembled AIE Dots for Cancer Theranostics Journal article
Frontiers in Bioengineering and Biotechnology, 2020,Volume: 8
Authors:  Yang,Xing;  Luo,Yuan;  Li,Sanpeng;  Xu,Xiuli;  Bao,Yingxia;  Yang,Jiaming;  Ouyang,Defang;  Fan,Xingxing;  Gong,Ping;  Cai,Lintao
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Aie  Cancer  Prodrug  Self-assembly  Theranostics  
Crystalline and magnetic structures, magnetization, heat capacity, and anisotropic magnetostriction effect in a yttrium-chromium oxide Journal article
Physical Review Materials, 2020,Volume: 4,Issue: 9
Authors:  Zhu,Yinghao;  Fu,Ying;  Tu,Bao;  Li,Tao;  Miao,Jun;  Zhao,Qian;  Wu,Si;  Xia,Junchao;  Zhou,Pengfei;  Huq,Ashfia;  Schmidt,Wolfgang;  Ouyang,Defang;  Tang,Zikang;  He,Zhubing;  Li,Hai Feng
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Super-necking crystal growth and structural and magnetic properties of SrTb2O4 single crystals Journal article
ACS Omega, 2020,Volume: 5,Issue: 27,Page: 16584-16594
Authors:  Chen,Zhenqiang;  Tang,Zikang;  Li,Hai Feng;  Wu,Si;  Zhu,Yinghao;  Gao,Haoshi;  Xiao,Yinguo;  Xia,Junchao;  Zhou,Pengfei;  Ouyang,Defang;  Li,Zhen
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