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ADME/T-based strategies for paraquat detoxification: Transporters and enzymes Journal article
Environmental Pollution, 2021,Volume: 291
Authors:  Wang, Xianzhe;  Wang, Xumei;  Zhu, Yanyan;  Chen, Xiuping
Favorite |  | TC[WOS]:0 TC[Scopus]:0 | Submit date:2021/12/08
Adme/t  Detoxification  Enzymes  Paraquat  Transporters  
Nannocystin ax, an eEF1A inhibitor, induces G1 cell cycle arrest and caspase-independent apoptosis through cyclin D1 downregulation in colon cancer in vivo Journal article
Pharmacological Research, 2021,Volume: 173
Authors:  Hou, Ying;  Liu, Rong;  Xia, Mengwei;  Sun, Chong;  Zhong, Bingling;  Yu, Jie;  Ai, Nana;  Lu, Jin Jian;  Ge, Wei;  Liu, Bo;  Chen, Xiuping
Favorite |  | TC[WOS]:0 TC[Scopus]:0 | Submit date:2021/12/08
Apoptosis  Cyclin D1  G1 Cell Cycle Arrest  Nannocystin Ax  
Small molecules targeting ubiquitination to control inflammatory diseases Journal article
Drug Discovery Today, 2021,Volume: 26,Issue: 10,Page: 2414-2422
Authors:  Li, Zheng Qing;  Chen, Xiuping;  Wang, Ying
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Inflammatory diseases  Small molecule modulator  Ubiquitin  Ubiquitination system  
Therapeutic potential of isobavachalcone, a natural flavonoid, in murine experimental colitis by inhibiting NF-κB p65 Journal article
Phytotherapy Research, 2021,Volume: 35,Issue: 10,Page: 5861-5870
Authors:  Zhou, Yishan;  Zhong, Bingling;  Min, Xiangjing;  Hou, Ying;  Lin, Ligen;  Wu, Qin;  Shi, Jingshan;  Chen, Xiuping
Favorite |  | TC[WOS]:1 TC[Scopus]:1 | Submit date:2021/12/08
inflammation  isobavachalcone  NF-κB p65  ulcerative colitis  
Regulation of CD47 expression by interferon-gamma in cancer cells Journal article
Translational Oncology, 2021,Volume: 14,Issue: 9
Authors:  Ye, Zi Han;  Jiang, Xiao Ming;  Huang, Mu Yang;  Xu, Yu Lian;  Chen, Yu Chi;  Yuan, Luo Wei;  Huang, Can Yu;  Yu, Wei Bang;  Chen, Xiuping;  Lu, Jin Jian
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Receptor-interacting serine/threonine-protein kinase 1 (RIPK1) inhibitors Necrostatin-1 (Nec-1) and 7-Cl-O-Nec-1 (Nec-1s) are potent inhibitors of NAD(P)H: Quinone oxidoreductase 1 (NQO1) Journal article
Free Radical Biology and Medicine, 2021,Volume: 173,Page: 64-69
Authors:  Yu, Jie;  Zhong, Bingling;  Zhao, Lin;  Hou, Ying;  Wang, Xianzhe;  Chen, Xiuping
Favorite |  | TC[WOS]:0 TC[Scopus]:0 | Submit date:2021/12/08
Nec-1  Nec-1s  NQO1  RIPK1  
Nannocystin Ax, a natural elongation factor 1α inhibitor from Nannocystis sp., suppresses epithelial-mesenchymal transition, adhesion and migration in lung cancer cells Journal article
Toxicology and Applied Pharmacology, 2021,Volume: 420
Authors:  Sun, Chong;  Liu, Rong;  Xia, Mengwei;  Hou, Ying;  Wang, Xumei;  Lu, Jin jian;  Liu, Bo;  Chen, Xiuping
Favorite |  | TC[WOS]:0 TC[Scopus]:0 | Submit date:2021/12/08
EMT  Lung cancer  Metastasis  Nannocystin Ax  
A novel strategy for glioblastoma treatment by induction of noptosis, an NQO1-dependent necrosis Journal article
Free Radical Biology and Medicine, 2021,Volume: 166,Page: 104-115
Authors:  Zhong, Bingling;  Yu, Jie;  Hou, Ying;  Ai, Nana;  Ge, Wei;  Lu, Jin Jian;  Chen, Xiuping
Favorite |  | TC[WOS]:1 TC[Scopus]:0 | Submit date:2021/09/17
Glioblastoma  Jnk1/2  Noptosis  Nqo1  Tanshindiol b  
Pharmacological review of isobavachalcone, a naturally occurring chalcone Journal article
Pharmacological Research, 2021,Volume: 165
Authors:  Wang,Miaojuan;  Lin,Ligen;  Lu,Jin Jian;  Chen,Xiuping
Favorite |  | TC[WOS]:3 TC[Scopus]:3 | Submit date:2021/03/01
Isobavachalcone  Molecular Targets  Pharmacokinetic  Pharmacology  
Dihydrotanshinone i Attenuates Plaque Vulnerability in Apolipoprotein E-Deficient Mice: Role of Receptor-Interacting Protein 3 Journal article
Antioxidants and Redox Signaling, 2021,Volume: 34,Issue: 5,Page: 351-363
Authors:  Zhao,Wenwen;  Li,Chunxia;  Zhang,Hao;  Zhou,Qihui;  Chen,Xuehong;  Han,Yantao;  Chen,Xiuping
Favorite |  | TC[WOS]:4 TC[Scopus]:5 | Submit date:2021/03/01
Apoe-/-mice  Rip3  Tlr4 Dimerization  Vulnerable