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Synthesis, biological evaluation and structure-activity relationship of novel dichloroacetophenones targeting pyruvate dehydrogenase kinases with potent anticancer activity Journal article
European Journal of Medicinal Chemistry, 2021,Volume: 214
Authors:  Xu,Biao;  Wang,Zhi Peng;  Liu,Qingwang;  Yang,Xiaohong;  Li,Xuemin;  Huang,Ding;  Qiu,Yanfei;  Tam,Kin Yip;  Zhang,Shao Lin;  He,Yun
Favorite |  | TC[WOS]:0 TC[Scopus]:0 | Submit date:2021/03/04
Cancer metabolism  Proliferation  Pyruvate dehydrogenase kinase  Structure-activity relationship  
Development of dual inhibitors targeting pyruvate dehydrogenase kinases and human lactate dehydrogenase A: High-throughput virtual screening, synthesis and biological validation Journal article
European Journal of Medicinal Chemistry, 2020,Volume: 203
Authors:  Xiang,Sichuan;  Huang,Ding;  He,Qiaolin;  Li,Jie;  Tam,Kin Yip;  Zhang,Shao Lin;  He,Yun
Favorite |  | TC[WOS]:2 TC[Scopus]:2 | Submit date:2021/03/04
Cancer metabolism  Cancer proliferation  Dual inhibitor  Lactate dehydrogenase A  Pyruvate dehydrogenase kinase  
Ethanol extract of Ophiorrhiza pumila suppresses liver cancer cell proliferation and migration Journal article
Chinese Medicine (United Kingdom), 2020,Volume: 15,Issue: 1
Authors:  Liu,Hui;  Liao,Wanqin;  Fan,Lixia;  Zheng,Zhaoguang;  Liu,Dahai;  Zhang,Qing Wen;  Yang,Anping;  Liu,Fang
Favorite |  | TC[WOS]:4 TC[Scopus]:4 | Submit date:2021/03/02
Apoptosis  Liver cancer  Migration  Ophiorrhiza pumila  Proliferation  
DNA replication licensing proteins: Saints and sinners in cancer Journal article
Seminars in Cancer Biology, 2019,Volume: 58,Page: 11-21
Authors:  Mughal,Muhammad Jameel;  Mahadevappa,Ravikiran;  Kwok,Hang Fai
Favorite |  | TC[WOS]:8 TC[Scopus]:8 | Submit date:2021/03/04
Cancer  DNA replication  Licensing proteins  Pre-replication complex  Proliferation  
DNA replication licensing protein MCM10 promotes tumor progression and is a novel prognostic biomarker and potential therapeutic target in breast cancer Journal article
Cancers, 2018,Volume: 10,Issue: 9
Authors:  Mahadevappa R.;  Neves H.;  Yuen S.M.;  Jameel M.;  Bai Y.;  Yuen H.-F.;  Zhang S.-D.;  Zhu Y.;  Lin Y.;  Kwok H.F.
Favorite |  | TC[WOS]:12 TC[Scopus]:11 | Submit date:2018/12/19
Breast Cancer  Knockdown  Mcm10  Overexpression  Proliferation  Survival  
B-Myb Is Up-Regulated and Promotes Cell Growth and Motility in Non-Small Cell Lung Cancer Journal article
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2017,Volume: 18,Issue: 6
Authors:  Jin, Yuelei;  Zhu, Huifang;  Cai, Wei;  Fan, Xiaoyan;  Wang, Yitao;  Niu, Yulong;  Song, Fangzhou;  Bu, Youquan
Favorite |  | TC[WOS]:13 TC[Scopus]:15 | Submit date:2018/11/01
B-Myb  lung cancer  proliferation  migration  extracellular signal-regulated kinases (ERK)  
Preparation and evaluation of I-131-quercetin as a novel radiotherapy agent against dedifferentiated thyroid cancer Journal article
JOURNAL OF RADIOANALYTICAL AND NUCLEAR CHEMISTRY, 2017,Volume: 311,Issue: 3,Page: 1697-1708
Authors:  Xie, Qinghua;  Li, Xia;  Wang, Guanquan;  Hou, Xuan;  Wang, Yujun;  Yu, Hongbo;  Qu, Changfa;  Luo, Shunzhong;  Cui, Yali;  Xia, Chuanqin;  Wang, Ruibing
Favorite |  | TC[WOS]:4 TC[Scopus]:3 | Submit date:2018/10/30
Dedifferentiated thyroid cancer  I-131-quercetin  Proliferation inhibition  Biodistribution  Radiopharmaceutical  
Preparation and evaluation of 131I-quercetin as a novel radiotherapy agent against dedifferentiated thyroid cancer Journal article
Journal of Radioanalytical and Nuclear Chemistry, 2017,Volume: 311,Issue: 3,Page: 1697-1708
Authors:  Xie Q.;  Li X.;  Wang G.;  Hou X.;  Wang Y.;  Yu H.;  Qu C.;  Luo S.;  Cui Y.;  Xia C.;  Wang R.
Favorite |  | TC[WOS]:4 TC[Scopus]:3 | Submit date:2018/11/06
131i-quercetin  Biodistribution  Dedifferentiated Thyroid Cancer  Proliferation Inhibition  Radiopharmaceutical  
Preparation and evaluation of 131I-quercetin as a novel radiotherapy agent against dedifferentiated thyroid cancer Journal article
Journal of Radioanalytical and Nuclear Chemistry, 2017,Volume: 311,Issue: 3,Page: 1697-1708
Authors:  Xie,Qinghua;  Li,Xia;  Wang,Guanquan;  Hou,Xuan;  Wang,Yujun;  Yu,Hongbo;  Qu,Changfa;  Luo,Shunzhong;  Cui,Yali;  Xia,Chuanqin;  Wang,Ruibing
Favorite |  | TC[WOS]:4 TC[Scopus]:3 | Submit date:2021/03/02
131I-quercetin  Biodistribution  Dedifferentiated thyroid cancer  Proliferation inhibition  Radiopharmaceutical  
Impact of fixed-dose combination of germacrone, curdione, and furanodiene on breast cancer cell proliferation Journal article
Cell Journal, 2013,Volume: 15,Issue: 2,Page: 160-165
Authors:  Kong Q.;  Sun F.;  Chen X.
Favorite |  | TC[WOS]:16 TC[Scopus]:0 | Submit date:2018/12/28
Breast Cancer  Chinese Medicine  Fixed-dose-combination  Intra-herbal Drug Interactions  Proliferation