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Acetyltanshinone IIA is more potent than lapatinib in inhibiting cell growth and degrading HER2 protein in drug-resistant HER2-positive breast cancer cells Journal article
Cancer Letters, 2020,Volume: 490,Page: 1-11
Authors:  Huang,Bin;  Yip,Wai Kien;  Wei,Na;  Luo,Kathy Qian
Favorite |  | TC[WOS]:2 TC[Scopus]:1 | Submit date:2021/03/02
Acetyltanshinone IIA  Drug resistance  HER2 degradation  HER2-positive breast cancer  
Artificial intelligence in cancer diagnosis and prognosis: Opportunities and challenges Journal article
Cancer Letters, 2019,Volume: 471,Page: 61-71
Authors:  Shigao Huang;  Jie Yang;  Simon Fong;  Qi Zhao
Favorite |  | TC[WOS]:24 TC[Scopus]:28 | Submit date:2021/03/04
Cancer Diagnosis  Prognosis Prediction  Deep Learning  Machine Learning  Deep Neural Network  
PTEN deficiency confers colorectal cancer cell resistance to dual inhibitors of FLT3 and aurora kinase A Journal article
CANCER LETTERS, 2018,Volume: 436,Page: 28-37
Authors:  Yifan Liu;  Eun Ju Yang;  Baoyuan Zhang;  Zhengqiang Miao;  Changjie Wu;  Junfang Lyu;  Kaeling Tan;  Terence Chuen Wai Poon;  Joong Sup Shim
Favorite |  | TC[WOS]:8 TC[Scopus]:6 | Submit date:2018/10/30
Akt  Kw2449  Synthetic Lethality  Aurka  Drug Combination  
Identification of a novel autophagic inhibitor cepharanthine to enhance the anti-cancer property of dacomitinib in non-small cell lung cancer Journal article
CANCER LETTERS, 2018,Volume: 412,Page: 1-9
Authors:  Tang, Zheng-Hai;  Cao, Wen-Xiang;  Guo, Xia;  Dai, Xiao-Yang;  Lu, Jia-Hong;  Chen, Xiuping;  Zhu, Hong;  Lu, Jin-Jian
Favorite |  | TC[WOS]:16 TC[Scopus]:18 | Submit date:2018/10/30
Cepharanthine  Autophagy  Lysosome  Dacomitinib  Nsclc  
Osimertinib resistance in non-small cell lung cancer: Mechanisms and therapeutic strategies Journal article
CANCER LETTERS, 2018,Volume: 420,Page: 242-246
Authors:  Tang, Zheng-Hai;  Lu, Jin-Jian
Favorite |  | TC[WOS]:54 TC[Scopus]:54 | Submit date:2018/10/30
Osimertinib  Azd9291  Egfr Tki  Resistant Mechanisms  Therapeutic Strategies  
Pharmacological blockade of cholesterol trafficking by cepharanthine in endothelial cells suppresses angiogenesis and tumor growth Journal article
CANCER LETTERS, 2017,Volume: 409,Page: 91-103
Authors:  Lyu, Junfang;  Yang, Eun Ju;  Head, Sarah A.;  Ai, Nana;  Zhang, Baoyuan;  Wu, Changjie;  Li, Ruo-Jing;  Liu, Yifan;  Yang, Chen;  Dang, Yongjun;  Kwon, Ho Jeong;  Ge, Wei;  Liu, Jun O.;  Shim, Joong Sup
Favorite |  | TC[WOS]:28 TC[Scopus]:25 | Submit date:2018/10/30
Cholesterol Trafficking  Angiogenesis  Tumor  Lysosome  Cepharanthine  
An anti-prostate cancer benzofuran-conjugated iridium(III) complex as a dual inhibitor of STAT3 and NF-kappa B Journal article
CANCER LETTERS, 2017,Volume: 396,Page: 76-84
Authors:  Kang, Tian-Shu;  Wang, Wanhe;  Zhong, Hai-Jing;  Dong, Zhen-Zhen;  Huang, Qi;  Mok, Simon Wing Fai;  Leung, Chung-Hang;  Wong, Vincent Kam Wai;  Ma, Dik-Lung
Favorite |  | TC[WOS]:50 TC[Scopus]:49 | Submit date:2018/10/30
Benzofuran-conjugated iridium(III) complex  STAT3  NF-kappa B  Prostate cells  Dual inhibitors  
Hemodynamic shear stress stimulates migration and extravasation of tumor cells by elevating cellular oxidative level Journal article
CANCER LETTERS, 2017,Volume: 388,Page: 239-248
Authors:  Ma, Shijun;  Fu, Afu;  Chiew, Geraldine Giap Ying;  Luo, Kathy Qian
Favorite |  | TC[WOS]:28 TC[Scopus]:26 | Submit date:2018/10/30
Circulating Tumor Cells  Shear Stress  Reactive Oxygen Species  Erk1/2  Cell Migration  Extravasation  
An anti-prostate cancer benzofuran-conjugated iridium(III) complex as a dual inhibitor of STAT3 and NF-κB Journal article
Cancer Letters, 2017,Volume: 396,Page: 76
Authors:  Kang T.-S.;  Wang W.;  Zhong H.-J.;  Dong Z.-Z.;  Huang Q.;  Mok S.W.F.;  Leung C.-H.;  Wong V.K.W.;  Ma D.-L.
Favorite |  | TC[WOS]:50 TC[Scopus]:49 | Submit date:2018/10/30
Benzofuran-conjugated Iridium(Iii) Complex  Dual Inhibitors  Nf-κb  Prostate Cells  Stat3  
NFκB up-regulation of glucose transporter 3 is essential for hyperactive mammalian target of rapamycin-induced aerobic glycolysis and tumor growth Journal article
Cancer Letters, 2015,Volume: 359,Issue: 1,Page: 97-106
Authors:  Zha X.;  Hu Z.;  Ji S.;  Jin F.;  Jiang K.;  Li C.;  Zhao P.;  Tu Z.;  Chen X.;  Di L.;  Zhou H.;  Zhang H.
Favorite |  | TC[WOS]:34 TC[Scopus]:34 | Submit date:2018/12/21
Aerobic Glycolysis  Glut3  Mtor  Nfκb  Tumorigenesis