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Development of a specific affinity-matured exosite inhibitor to MT1-MMP that efficiently inhibits tumor cell invasion in vitro and metastasis in vivo Journal article
Oncotarget, 2016,Volume: 7,Issue: 13,Page: 16773-16792
Authors:  Botkjaer K.A.;  Kwok H.F.;  Terp M.G.;  Karatt-Vellatt A.;  Santamaria S.;  McCafferty J.;  Andreasen P.A.;  Itoh Y.;  Ditzel H.J.;  Murphy G.
Favorite |  | TC[WOS]:27 TC[Scopus]:26 | Submit date:2018/12/19
Antibody  In Vivo targetIng  Metastasis  Mt1-mmp  Non-catalytic Sites  
Development of a 'mouse and human cross-reactive' affinity-matured exosite inhibitory human antibody specific to TACE (ADAM17) for cancer immunotherapy Journal article
Protein Engineering, Design and Selection, 2014,Volume: 27,Issue: 6,Page: 179-190
Authors:  Kwok H.F.;  Botkjaer K.A.;  Tape C.J.;  Huang Y.;  McCafferty J.;  Murphy G.
Favorite |  | TC[WOS]:22 TC[Scopus]:22 | Submit date:2018/12/19
Anti-tace Antibody  Exosite  Immunoreactivity  Phage-display Randomization Libraries  Sub-nanomolar Affinity