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TDP-1/TDP-43 potentiates human α-Synuclein (HASN) neurodegeneration in Caenorhabditis elegans Journal article
Biochimica et Biophysica Acta - Molecular Basis of Disease, 2020,Volume: 1866,Issue: 10
Authors:  Shen,Linjing;  Wang,Changliang;  Chen,Liang;  Leung,Ka Lai;  Lo,Esther;  Lakso,Merja;  Wong,Garry
Favorite |  | TC[WOS]:5 TC[Scopus]:3 | Submit date:2021/03/02
C. Elegans  Lewy Body Dementia  Neurodegeneration  Parkinson's Disease  Tdp-1/tdp-43  Tdp-43  Α-synuclein  
Oxyphylla a promotes degradation of α-synuclein for neuroprotection via activation of immunoproteasome Journal article
Aging and Disease, 2020,Volume: 11,Issue: 3,Page: 559-574
Authors:  Zhou,Hefeng;  Li,Shengnan;  Li,Chuwen;  Yang,Xuanjun;  Li,Haitao;  Zhong,Hanbing;  Lu,Jia Hong;  Lee,Simon Ming Yuen
Favorite |  | TC[WOS]:1 TC[Scopus]:1 | Submit date:2021/03/01
Degradation  Neuroprotection  Parkinson's disease  Proteasome  α-synuclein  
Inhibition of alpha-synuclein seeded fibril formation and toxicity by herbal medicinal extracts Journal article
BMC complementary medicine and therapies, 2020,Volume: 20,Issue: 1
Authors:  Ardah,Mustafa T.;  Ghanem,Simona S.;  Abdulla,Sara A.;  Lv,Guohua;  Emara,Mohamed M.;  Paleologou,Katerina E.;  Vaikath,Nishant N.;  Lu,Jia Hong;  Li,Min;  Vekrellis,Konstantinos;  Eliezer,David;  El-Agnaf,Omar M.A.
Favorite |  | TC[WOS]:2 TC[Scopus]:4 | Submit date:2021/03/02
Amyloid fibrils  Dihydromyricetin  Parkinson’s disease  Salvianolic acid B  Seeded fibril formation  α-Synuclein  
A curcumin derivative activates TFEB and protects against parkinsonian neurotoxicity in vitro Journal article
International Journal of Molecular Sciences, 2020,Volume: 21,Issue: 4
Authors:  Wang,Ziying;  Yang,Chuanbin;  Liu,Jia;  Tong,Benjamin Chun Kit;  Zhu,Zhou;  Malampati,Sandeep;  Sreenivasmurthy,Sravan Gopalkrishnashetty;  Cheung,King Ho;  Iyaswamy,Ashok;  Su,Chengfu;  Lu,Jiahong;  Song,Juxian;  Li,Min
Favorite |  | TC[WOS]:6 TC[Scopus]:6 | Submit date:2021/03/02
Curcumin derivatives  MTORC1  Parkinson’s disease  TFEB  α-synuclein  
Autophagy and parkinson’s disease Book chapter
出自: Advances in Experimental Medicine and Biology, 2020, 页码: 21-51
Authors:  Lu,Jiahong;  Wu,Mingyue;  Yue,Zhenyu
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Autophagy  Parkinson disease  α-synuclein  
Tetramethylpyrazine Analogue T-006 Promotes the Clearance of Alpha-synuclein by Enhancing Proteasome Activity in Parkinson’s Disease Models Journal article
Neurotherapeutics, 2019,Volume: 16,Issue: 4,Page: 1225-1236
Authors:  Zhou,Hefeng;  Shao,Min;  Guo,Baojian;  Li,Chuwen;  Lu,Yucong;  Yang,Xuanjun;  ShengnanLi,;  Li,Haitao;  Zhu,Qi;  Zhong,Hanbing;  Wang,Yuqiang;  Zhang,Zaijun;  Lu,Jiahong;  Lee,Simon Ming Yuen
Favorite |  | TC[WOS]:7 TC[Scopus]:7 | Submit date:2021/03/01
Degradation  LMP7  Parkinson’s disease  Proteasome activity  α-synuclein  
Natural alkaloid harmine promotes degradation of alpha-synuclein via PKA-mediated ubiquitin-proteasome system activation Journal article
Phytomedicine, 2019,Volume: 61
Authors:  Cai,Cui Zan;  Zhou,He Feng;  Yuan,Ning Ning;  Wu,Ming Yue;  Lee,Simon Ming Yuen;  Ren,Jiao Yan;  Su,Huan Xing;  Lu,Jin Jian;  Chen,Xiu Ping;  Li,Min;  Tan,Jie Qiong;  Lu,Jia Hong
Favorite |  | TC[WOS]:9 TC[Scopus]:8 | Submit date:2021/03/01
-synuclein  Harmine  Parkinson's Disease  Protein Kinase a  Ubiquitin-proteasome System  
Canthin-6-One Accelerates Alpha-Synuclein Degradation by Enhancing UPS Activity: Drug Target Identification by CRISPR-Cas9 Whole Genome-Wide Screening Technology Journal article
FRONTIERS IN PHARMACOLOGY, 2019
Authors:  Ning-Ning Yuan;  Cui-Zan Cai;  Ming-Yue Wu;  Qi Zhu;  HuanXing Su;  Min Li;  JiaoYan Ren;  Jie-Qiong Tan;  Jia-Hong Lu
Favorite |  | TC[WOS]:5 TC[Scopus]:7 | Submit date:2020/04/14
Canthin-6-one  Parkinson’s Disease  Alpha-synuclein  Ubiquitin-proteasome-system  Crispr/cas9  Rpn2/psmd1  Pka  
Perspectives on Caenorhabditis elegans models of human Parkinson's Disease Journal article
ADMET and DMPK, 2015,Volume: 3,Issue: 2,Page: 122-130
Authors:  Rudgalvyte,Martina;  Wong,Garry
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Dopamine  Keyword  Nematode  Neurodegeneration  Synuclein  Transgenic model  
Ginsenoside Rb1 inhibits fibrillation and toxicity of alpha-synuclein and disaggregates preformed fibrils Journal article
Neurobiology of Disease, 2015,Volume: 74,Page: 89
Authors:  Ardah M.T.;  Paleologou K.E.;  Lv G.;  Menon S.A.;  Abul Khair S.B.;  Lu J.-H.;  Safieh-Garabedian B.;  Al-Hayani A.A.;  Eliezer D.;  Li M.;  El-Agnaf O.M.A.
Favorite |  | TC[WOS]:50 TC[Scopus]:51 | Submit date:2018/10/30
Aggregation  Amyloid Fibrils  Drug Discovery  Ginsenosides  Parkinson's Disease  Α-synuclein