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Canthin-6-One Accelerates Alpha-Synuclein Degradation by Enhancing UPS Activity: Drug Target Identification by CRISPR-Cas9 Whole Genome-Wide Screening Technology Journal article
FRONTIERS IN PHARMACOLOGY, 2019
Authors:  Ning-Ning Yuan;  Cui-Zan Cai;  Ming-Yue Wu;  Qi Zhu;  HuanXing Su;  Min Li;  JiaoYan Ren;  Jie-Qiong Tan;  Jia-Hong Lu
Favorite |  | TC[WOS]:4 TC[Scopus]:6 | Submit date：2020/04/14
Canthin-6-one  Parkinson’s Disease  Alpha-synuclein  Ubiquitin-proteasome-system  Crispr/cas9  Rpn2/psmd1  Pka  
Natural autophagy blockers, dauricine (DAC) and daurisoline (DAS), sensitize cancer cells to camptothecin-induced toxicity Journal article
ONCOTARGET, 2017,Volume: 8,Issue: 44,Page: 77673-77684
Authors:  Wu, Ming-Yue;  Wang, Sheng-Fang;  Cai, Cui-Zan;  Tan, Jie-Qiong;  Li, Min;  Lu, Jin-Jian;  Chen, Xiu-Ping;  Wang, Yi-Tao;  Zheng, Wei;  Lu, Jia-Hong
Favorite |  | TC[WOS]:9 TC[Scopus]:13 | Submit date：2018/10/30
Dauricine  Daurisoline  Autophagy Blocker  Cancer Cells  Cell Toxicity  
BAG5 Interacts with DJ-1 and Inhibits the Neuroprotective Effects of DJ-1 to Combat Mitochondrial Oxidative Damage Journal article
OXIDATIVE MEDICINE AND CELLULAR LONGEVITY, 2017
Authors:  Qin, Li-Xia;  Tan, Jie-qiong;  Zhang, Hai-nan;  Rizwana, Kousar;  Lu, Jia-hong;  Tang, Jian-guang;  Jiang, Bo;  Shen, Xiang-min;  Guo, Ji-feng;  Tang, Bei-sha;  Tan, Li-ming;  Wang, Chun-yu
Favorite |  | TC[WOS]:7 TC[Scopus]:11 | Submit date：2018/10/30
NRBF2 is involved in the autophagic degradation process of APP-CTFs in Alzheimer disease models Journal article
AUTOPHAGY, 2017,Volume: 13,Issue: 12,Page: 2028-2040
Authors:  Yang, Chuanbin;  Cai, Cui-Zan;  Song, Ju-Xian;  Tan, Jie-Qiong;  Durairajan, Siva Sundara Kumar;  Iyaswamy, Ashok;  Wu, Ming-Yue;  Chen, Lei-Lei;  Yue, Zhenyu;  Li, Min;  Lu, Jia-Hong
Favorite |  | TC[WOS]:25 TC[Scopus]:25 | Submit date：2018/10/30
a Beta  Alzheimer's Disease  App  Autophagy  Class Iii Phosphatidylinositol 3-kinase (Ptdins3k)  Nrbf2