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Identification of nagilactone E as a protein synthesis inhibitor with anticancer activity Journal article
Acta Pharmacologica Sinica, 2020,Volume: 41,Issue: 5,Page: 698-705
Authors:  Zhang,Le le;  Guo,Jing;  Jiang,Xiao ming;  Chen,Xiu ping;  Wang,Yi tao;  Li,Ao;  Lin,Li gen;  Li,Hua;  Lu,Jin jian
Favorite |  | TC[WOS]:6 TC[Scopus]:6 | Submit date:2021/03/01
Click-iT  CMap  diterpenoids  human lung cancer A549 cell line xenograft  molecular docking  nagilactone E  protein synthesis inhibitor  RIOK2  RNA-seq  
TGFβ2-mediated epithelial–mesenchymal transition and NF-κB pathway activation contribute to osimertinib resistance Journal article
Acta Pharmacologica Sinica, 2020
Authors:  Jiang,Xiao ming;  Xu,Yu lian;  Yuan,Luo wei;  Zhang,Le le;  Huang,Mu yang;  Ye,Zi han;  Su,Min xia;  Chen,Xiu ping;  Zhu,Hong;  Ye,Richard D.;  Lu,Jin jian
Favorite |  | TC[WOS]:3 TC[Scopus]:2 | Submit date:2021/03/01
EGFR mutant non-small cell lung cancer  epithelial-mesenchymal transition  NF-κB  osimertinib resistance  TGFβ2  
Post-translational modification of KRAS: potential targets for cancer therapy Journal article
Acta Pharmacologica Sinica, 2020
Authors:  Wang,Wei hua;  Yuan,Tao;  Qian,Mei jia;  Yan,Fang jie;  Yang,Liu;  He,Qiao jun;  Yang,Bo;  Lu,Jin jian;  Zhu,Hong
Favorite |  | TC[WOS]:1 TC[Scopus]:0 | Submit date:2021/03/02
acetylation  cancer therapy  KRAS  nitrosylation  oncogene  palmitoylation  phosphorylation  post-translational modification  postprenylation  prenylation  SUMOylation  ubiquitination  
Post-translational modification of KRAS: potential targets for cancer therapy Journal article
Acta Pharmacologica Sinica, 2020
Authors:  Wang,Wei hua;  Yuan,Tao;  Qian,Mei jia;  Yan,Fang jie;  Yang,Liu;  He,Qiao jun;  Yang,Bo;  Lu,Jin jian;  Zhu,Hong
Favorite |  | TC[WOS]:1 TC[Scopus]:0 | Submit date:2021/03/02
acetylation  cancer therapy  KRAS  nitrosylation  oncogene  palmitoylation  phosphorylation  post-translational modification  postprenylation  prenylation  SUMOylation  ubiquitination  
Platycodin D induces apoptosis and triggers ERK- and JNK-mediated autophagy in human hepatocellular carcinoma BEL-7402 cells Journal article
Acta Pharmacologica Sinica, 2015,Volume: 36,Issue: 12,Page: 1503-1513
Authors:  Ting Li;  Xiao-huang Xu;  Zheng-hai Tang;  Ya-fang Wang;  Chung-hang Leung;  Dik-lung Ma;  Xiu-ping Chen;  Yi-tao Wang;  Yi Chen;  Jin-jian Lu
Favorite |  | TC[WOS]:32 TC[Scopus]:33 | Submit date:2018/10/31
Apoptosis  Autophagy  Erk  Baf  Bel-7402 Cells  Chloroquine  Human Hepatocellular Carcinoma  Jnk  Platycodin d  Sp600125  U0126