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Supramolecular strategy for reducing the cardiotoxicity of bedaquiline without compromising its antimycobacterial efficacy Conference paper
FOOD AND CHEMICAL TOXICOLOGY, Kunming, PEOPLES R CHINA, AUG 25-30, 2018
Authors:  Kuok, Kit Ieng;  Ng, Phoebe Choi In;  Ji, Xia;  Wang, Chunming;  Yew, Wing Wai;  Chan, Denise P. C.;  Zheng, Jun;  Lee, Simon M. Y.;  Wang, Ruibing
View | Adobe PDF | Favorite |  | TC[WOS]:5 TC[Scopus]:5 | Submit date:2018/10/30
Cucurbit[7]Uril  Bedaquiline  Supramolecular Formulation  Cardiotoxicity  Antimycobacterial  
Novel Kunitz-like Peptides Discovered in the Zoanthid Palythoa caribaeorum through Transcriptome Sequencing Journal article
JOURNAL OF PROTEOME RESEARCH, 2018,Volume: 17,Issue: 2,Page: 891-902
Authors:  Liao, Qiwen;  Li, Shengnan;  Siu, Shirley Weng In;  Yang, Binrui;  Huang, Chen;  Chan, Judy Yuet-Wa;  Morlighem, Jean-Etienne R. L.;  Wong, Clarence Tsun Ting;  Radis-Baptista, Gandhi;  Lee, Simon Ming-Yuen
Favorite |  | TC[WOS]:10 TC[Scopus]:9 | Submit date:2018/10/30
Soft Coral  Transcriptome  Kunitz-like Peptides  Protein Docking Zebrafish  Neurotoxin  Zoanthids  
Substantial protection against MPTP-associated Parkinson's neurotoxicity in vitro and in vivo by anti-cancer agent SU4312 via activation of MEF2D and inhibition of MAO-B Journal article
NEUROPHARMACOLOGY, 2017,Volume: 126,Page: 12-24
Authors:  Guo, Baojian;  Hu, Shengquan;  Zheng, Chengyou;  Wang, Hongyu;  Luo, Fangcheng;  Li, Haitao;  Cui, Wei;  Yang, Xifei;  Cui, Guozhen;  Mak, Shinghung;  Choi, Tony Chung-Lit;  Ma, Edmond Dik-Lung;  Wang, Yuqiang;  Lee, Simon Ming Yuen;  Zhang, Zaijun;  Han, Yifan
View | Adobe PDF | Favorite |  | TC[WOS]:13 TC[Scopus]:14 | Submit date:2018/10/31
Parkinson's disease  SU4312  Neuroprotection  Myocyte enhancer factor 2D  Monoamine oxidase-B  
Pluronic P85/F68 Micelles of Baicalein Could Interfere with Mitochondria to Overcome MRP2-Mediated Efflux and Offer Improved Anti-Parkinsonian Activity Journal article
Molecular Pharmaceutics, 2017,Volume: 14,Issue: 10,Page: 3331-3342
Authors:  Tongkai Chen;  Ye Li;  Chuwen Li;  Xiang Yi;  Ruibing Wang;  Simon Ming-Yuen Lee;  Ying Zheng
Favorite |  | TC[WOS]:13 TC[Scopus]:15 | Submit date:2018/11/06
Baicalein  Fluorescence Resonance Energy Transfer (Fret)  Micelles  Mitochondria  Multidrug Resistance-associated Protein 2 (Mrp2)  Neuroprotective Effect  
An andrographolide derivative AGP-26b exibitiing anti-angiogenic activity in HUVECs and zebrafish via blocking the VEGFA/VEGFR2 signaling pathway Journal article
MOLECULAR BIOSYSTEMS, 2017,Volume: 13,Issue: 3,Page: 525-536
Authors:  Huang, Bin;  Peng, Yuran;  Li, Jingjing;  Li, Shang;  Sun, Yicheng;  Wang, Decai;  Yang, Binrui;  Chan, Judy Yuet-Wa;  Yu, Huidong;  Leung, George Pak-Heng;  Hoi, Maggie Pui-Man;  Zhou, Guo-Chun;  Lee, Simon Ming-Yuen
Adobe PDF | Favorite |  | TC[WOS]:5 TC[Scopus]:6 | Submit date:2018/10/30
Characterization of the Molecular Mechanisms Underlying the Chronic Phase of Stroke in a Cynomolgus Monkey Model of Induced Cerebral Ischemia Journal article
JOURNAL OF PROTEOME RESEARCH, 2017,Volume: 16,Issue: 3,Page: 1150-1166
Authors:  Law, Henry C. H.;  Szeto, Samuel S. W.;  Quan, Quan;  Zhao, Yun;  Zhang, Zaijun;  Krakovska, Olga;  Lui, Leong Ting;  Zheng, Chengyou;  Lee, Simon M. -Y.;  Siu, K. W. Michael;  Wang, Yuqiang;  Chu, Ivan K.
Favorite |  | TC[WOS]:8 TC[Scopus]:8 | Submit date:2018/10/30
Stroke Biology  Itraq  Cynomolgus Monkey  Brain Proteome  Ischemia  Chronic Phase  
Discovery of a novel ROCK2 inhibitor with anti-migration effects: Via docking and high-content drug screening Journal article
Molecular BioSystems, 2016,Volume: 12,Issue: 9,Page: 2713-2721
Authors:  Cheong-Meng Chong;  Man-Teng Kou;  Peichen Pan;  Hefeng Zhou;  Nana Ai;  Chuwen Li;  Hai-Jing Zhong;  Chung-Hang Leung;  Tingjun Hou;  Simon Ming-Yuen Lee
Favorite |  | TC[WOS]:7 TC[Scopus]:5 | Submit date:2018/11/06
A Novel Danshensu Derivative Prevents Cardiac Dysfunction and Improves the Chemotherapeutic Efficacy of Doxorubicin in Breast Cancer Cells Journal article
Journal of Cellular Biochemistry, 2016,Volume: 117,Issue: 1,Page: 94-105
Authors:  Liang Wang;  Xiaojing Zhang;  Judy Yuet‐Wa Chan;  Luchen Shan;  Guozhen Cui;  Qingbin Cui;  Yingfei Wang;  Jingjing Li;  Huanxian Chen;  Qingwen Zhang;  Pei Yu;  Yifan Han;  Yuqiang Wang;  Simon Ming‐Yuen Lee
Favorite |  | TC[WOS]:20 TC[Scopus]:22 | Submit date:2018/11/06
Breast Cancer  Cardiotoxicity  Doxorubicin  Mitochondrial Biogenesis  
Identification of an Iridium(III)-Based Inhibitor of Tumor Necrosis Factor-α Journal article
Journal of Medicinal Chemistry, 2016,Volume: 59,Issue: 8,Page: 4026
Authors:  Kang T.-S.;  Mao Z.;  Ng C.-T.;  Wang M.;  Wang W.;  Wang C.;  Lee S.M.-Y.;  Wang Y.;  Leung C.-H.;  Ma D.-L.
Favorite |  | TC[WOS]:38 TC[Scopus]:38 | Submit date:2018/10/30
Discovery of a novel ROCK2 inhibitor with anti-migration effects via docking and high-content drug screening Journal article
MOLECULAR BIOSYSTEMS, 2016,Volume: 12,Issue: 9,Page: 2713-2721
Authors:  Cheong-Meng Chong;  Man-Teng Kou;  Peichen Pan;  Hefeng Zhou;  Nana Ai;  Chuwen Li;  Hai-Jing Zhong;  Chung-Hang Leung;  Tingjun Hou;  Simon Ming-Yuen Lee
Favorite |  | TC[WOS]:7 TC[Scopus]:5 | Submit date:2020/07/30