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Enhanced Protein Damage Clearance Induces Broad Drug Resistance in Multitype of Cancers Revealed by an Evolution Drug-Resistant Model and Genome-Wide siRNA Screening Journal article
Advanced Science, 2020,Volume: 7,Issue: 23
Authors:  Shao,Fangyuan;  Lyu,Xueying;  Miao,Kai;  Xie,Lisi;  Wang,Haitao;  Xiao,Hao;  Li,Jie;  Chen,Qiang;  Ding,Renbo;  Chen,Ping;  Xing,Fuqiang;  Zhang,Xu;  Luo,Guang Hui;  Zhu,Wenli;  Cheng,Gregory;  Lon,Ng Wai;  Martin,Scott E.;  Wang,Guanyu;  Chen,Guokai;  Dai,Yunlu;  Deng,Chu Xia
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Broad Drug Resistance  Caspase 3 Activation  Patient-derived Organoid  Proteolysis  Rnai Screening  
Nagilactone E increases PD-L1 expression through activation of c-Jun in lung cancer cells Journal article
Chinese Journal of Natural Medicines, 2020,Volume: 18,Issue: 7,Page: 517-525
Authors:  CHEN,Yu Chi;  HUANG,Mu Yang;  ZHANG,Le Le;  FENG,Zhe Ling;  JIANG,Xiao Ming;  YUAN,Luo Wei;  HUANG,Run Yue;  LIU,Bo;  YU,Hua;  WANG,Yi Tao;  CHEN,Xiu Ping;  LIN,Li Gen;  LU,Jin Jian
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C-jun  Jnk  Lung Cancer  Nagilactone e  Programmed Death Ligand 1  
Pristimerin-induced uveal melanoma cell death via inhibiting PI3K/Akt/FoxO3a signalling pathway Journal article
Journal of Cellular and Molecular Medicine, 2020,Volume: 24,Issue: 11,Page: 6208-6219
Authors:  Yan,Fengxia;  Liao,Rifang;  Silva,Marta;  Li,Shuai;  Jiang,Yizhou;  Peng,Tangming;  Lazarovici,Philip;  Zheng,Wenhua
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cell death  FoxO3a  nuclear accumulation  Pristimerin  uveal melanoma  
Activation of notch 3/c-MYC/CHOP axis regulates apoptosis and promotes sensitivity of lung cancer cells to mTOR inhibitor everolimus Journal article
Biochemical Pharmacology, 2020,Volume: 175
Authors:  Li,Ting;  Xu,Xiao Huang;  Guo,Xia;  Yuan,Tao;  Tang,Zheng Hai;  Jiang,Xiao Ming;  Xu,Yu Lian;  Zhang,Le Le;  Chen,Xiuping;  Zhu,Hong;  Shi,Jia Jie;  Lu,Jin Jian
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Apoptosis  c-MYC  CHOP  Lung cancer  Notch 3  
Botanical drug puerarin promotes neuronal survival and neurite outgrowth against mptp/mpp+-induced toxicity via progesterone receptor signaling Journal article
Oxidative Medicine and Cellular Longevity, 2020,Volume: 2020
Authors:  Zhao,Yingke;  Zhao,Jia;  Zhang,Xiuying;  Cheng,Yuanyuan;  Luo,Dan;  Lee,Simon Ming Yuen;  Lao,Lixing;  Rong,Jianhui
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Phanginin R induces cytoprotective autophagy via JNK/C-JUN signaling pathway in non-small cell lung cancer A549 cells Journal article
Anti-Cancer Agents in Medicinal Chemistry, 2020,Volume: 20,Issue: 8,Page: 982-988
Authors:  Zhang,Le Le;  Bao,Han;  Xu,Yu Lian;  Jiang,Xiao Ming;  Li,Wei;  Zou,Liang;  Lin,Li Gen;  Lu,Jin Jian
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Anti-cancer  Autophagy  C-Jun  JNK  Non-small cell lung cancer  Phanginin R  
Foxo3a suppresses neuropeptide w expression in neuronal cells and in rat hypothalamus and its implication in hypothalamic-pituitary-adrenal (HPA) axis Journal article
International Journal of Biological Sciences, 2020,Volume: 16,Issue: 15,Page: 2775-2787
Authors:  Yan,Fengxia;  Wang,Rikang;  Li,Shuai;  Zhao,Xia;  Jiang,Yizhou;  Liu,Linlin;  Fang,Jiankang;  Zhen,Xuechu;  Lazarovici,Philip;  Zheng,Wenhua
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FoxO3a  Glucocorticoids  HPA axis dysfunction  Hypothalamus  Neuropeptide W (NPW)  
Quercetin induces p53-independent cancer cell death through lysosome activation by the transcription factor EB and Reactive Oxygen Species-dependent ferroptosis Journal article
British Journal of Pharmacology, 2020
Authors:  Wang,Zi Xuan;  Ma,Jing;  Li,Xin Yu;  Wu,Yong;  Shi,Huan;  Chen,Yao;  Lu,Guang;  Shen,Han Ming;  Lu,Guo Dong;  Zhou,Jing
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ferroptosis  lysosome  quercetin  ROS  transcription factor EB  
Corin plays a protective role via upregulating MAPK and downregulating eNOS in diabetic nephropathy endothelial dysfunction Journal article
FASEB Journal, 2020,Volume: 34,Issue: 1,Page: 95-106
Authors:  Xue,Meiting;  Shi,Yue;  Pang,Aiming;  Men,Li;  Hu,Yahui;  Zhou,Pengfei;  Long,Guangfeng;  Tian,Xin;  Wang,Rong;  Zhao,Yonghua;  Liao,Xudong;  Shen,Yanna;  Cui,Yujie
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Corin  Diabetic Nephropathy  Endothelial Dysfunction  Enos  Mapk  
An integrative multi-omics approach uncovers the regulatory role of CDK7 and CDK4 in autophagy activation induced by silica nanoparticles Journal article
Autophagy, 2020
Authors:  Ruan,Chen;  Wang,Chenwei;  Gong,Xuanqing;  Zhang,Ying;  Deng,Wankun;  Zhou,Jiaqi;  Huang,Dengtong;  Wang,Zining;  Zhang,Qiong;  Guo,Anyuan;  Lu,Jiahong;  Gao,Jinhao;  Peng,Di;  Xue,Yu
Favorite |  | TC[WOS]:4 TC[Scopus]:3 | Submit date:2021/03/02
Autophagy  CDK4  CDK7  phosphoproteomics  protein kinase  silica nanoparticles