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Simultaneous blocking of the pan-RAF and S100B pathways as a synergistic therapeutic strategy against malignant melanoma Journal article
Journal of Cellular and Molecular Medicine, 2021,Volume: 25,Issue: 4,Page: 1972-1981
Authors:  Wu,Ke Jia;  Ho,Shih Hsin;  Wu,Chun;  Wang,Hui Min D.;  Ma,Dik Lung;  Leung,Chung Hang
Favorite |  | TC[WOS]:0 TC[Scopus]:0 | Submit date:2021/03/01
drug discovery  malignant melanoma  pan-RAF  S100B-p53 interaction  synergistic  
The role of autophagy in liver cancer: Crosstalk in signaling pathways and potential therapeutic targets Journal article
Pharmaceuticals, 2020,Volume: 13,Issue: 12,Page: 1-27
Authors:  Cui,Jianzhou;  Shen,Han Ming;  Lim,Lina Hsiu Kim
Favorite |  | TC[WOS]:0 TC[Scopus]:0 | Submit date:2021/03/02
AMPK  Autophagy  HCC  MAPK  MTOR  P53  ULK1  
Characterization of BRCA1-deficient premalignant tissues and cancers identifies Plekha5 as a tumor metastasis suppressor Journal article
Nature Communications, 2020,Volume: 11,Issue: 1
Authors:  Liu,Jianlin;  Adhav,Ragini;  Miao,Kai;  Su,Sek Man;  Mo,Lihua;  Chan,Un In;  Zhang,Xin;  Xu,Jun;  Li,Jianjie;  Shu,Xiaodong;  Zeng,Jianming;  Zhang,Xu;  Lyu,Xueying;  Pardeshi,Lakhansing;  Tan,Kaeling;  Sun,Heng;  Wong,Koon Ho;  Deng,Chuxia;  Xu,Xiaoling
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Silica nanoparticles induce spermatogenesis disorders via L3MBTL2-DNA damage-p53 apoptosis and RNF8-ubH2A/ubH2B pathway in mice Journal article
Environmental Pollution, 2020,Volume: 265
Authors:  Liu,Jianhui;  Li,Xiangyang;  Zhou,Guiqing;  Sang,Yujian;  Zhang,Yue;  Zhao,Yanzhi;  Ge,Wei;  Sun,Zhiwei;  Zhou,Xianqing
Favorite |  | TC[WOS]:0 TC[Scopus]:3 | Submit date:2021/03/02
Histone-to-protamine exchange  L3MBTL2  P53 apoptosis pathway  RNF8-ubH2A/ubH2B pathway  Silica nanoparticles  
Interfering with S100B–effector protein interactions for cancer therapy Journal article
Drug Discovery Today, 2020,Volume: 25,Issue: 9,Page: 1754-1761
Authors:  Wu,Ke Jia;  Wang,Wanhe;  Wang,Hui Min David;  Leung,Chung Hang;  Ma,Dik Lung
Favorite |  | TC[WOS]:1 TC[Scopus]:1 | Submit date:2021/03/01
Combining Ramachandran plot and molecular dynamics simulation for structural-based variant classification: Using TP53 variants as model Journal article
Computational and Structural Biotechnology Journal, 2020,Volume: 18,Page: 4033-4039
Authors:  Tam,Benjamin;  Sinha,Siddharth;  Wang,San Ming
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Molecular Dynamic Simulation  Pathogenic  Protein structure  Ramachandran plot  TP53  Variant of Uncertain Significance  
Anti-cancer effects of polyphenols via targeting p53 signaling pathway: updates and future directions Journal article
Biotechnology Advances, 2020,Volume: 38
Authors:  Khan,Haroon;  Reale,Marcella;  Ullah,Hammad;  Sureda,Antoni;  Tejada,Silvia;  Wang,Ying;  Zhang,Zhang Jin;  Xiao,Jianbo
Favorite |  | TC[WOS]:32 TC[Scopus]:32 | Submit date:2021/03/02
Anticancer  Chemoresistance  Clinical perspectives  p53 signaling pathways  Polyphenols  
A Danshensu-Tetramethylpyrazine Conjugate DT-010 Overcomes Multidrug Resistance in Human Breast Cancer Journal article
FRONTIERS IN PHARMACOLOGY, 2019,Volume: 10
Authors:  Xinhua Zhou;  Anqi Wang;  Liang Wang;  Jianhua Yin;  Li Wang;  Lijun Di;  Maggie Pui-Man Hoi;  Luchen Shan;  Xu Wu;  Yuqiang Wang
Favorite |  | TC[WOS]:3 TC[Scopus]:4 | Submit date:2020/05/21
Danshensu  Tetramethylpyrazine  Breast Cancer  Resistance  Glycolysis  P-glycoprotein  
Combined use of arginase and dichloroacetate exhibits anti-proliferative effects in triple negative breast cancer cells Journal article
JOURNAL OF PHARMACY AND PHARMACOLOGY, 2019,Volume: 71,Issue: 3,Page: 306-315
Authors:  Angela Verma;  Yau-Min Lam;  Yun-Chung Leung;  Xiaohui Hu;  Xin Chen;  Edwin Cheung;  Kin Yip Tam
Favorite |  | TC[WOS]:8 TC[Scopus]:8 | Submit date:2020/05/21
Bacillus Caldovelox Arginase  Breast Cancer  Dichloroacetate  Drug Combination  Pegyated Human Arginase  
PP2AC alpha deficiency impairs early cortical development through inducing DNA damage in neuroprojenitor cells Journal article
INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY, 2019,Volume: 109,Page: 40-58
Authors:  Bo Liu;  Lin Lin;  Saima Riazuddin;  Ahmed Zubair;  Li Wang;  Li-Jun Di;  Rui Li;  Ting-Ting Dong;  Chu-Xia Deng;  Wei-Min Tong
Favorite |  | TC[WOS]:2 TC[Scopus]:1 | Submit date:2020/05/26
Protein Phosphorylation  Brain Development  Dna Damage  Stem Cell  Signaling Cascade