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Metabolic reprogramming of ovarian cancer involves ACSL1-mediated metastasis stimulation through upregulated protein myristoylation Journal article
Oncogene, 2021,Volume: 40,Issue: 1,Page: 97-111
Authors:  Zhang,Qingyu;  Zhou,Wei;  Yu,Shan;  Ju,Yaojun;  To,Sally Kit Yan;  Wong,Alice Sze Tsai;  Jiao,Yufei;  Poon,Terence Chuen Wai;  Tam,Kin Yip;  Lee,Leo Tsz On
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Upregulation of amplified in breast cancer 1 contributes to pancreatic ductal adenocarcinoma progression and vulnerability to blockage of hedgehog activation Journal article
Theranostics, 2021,Volume: 11,Issue: 4,Page: 1672-1689
Authors:  Li,Licen;  Bao,Jiaolin;  Wang,Haitao;  Lei,Josh Haipeng;  Peng,Cheng;  Zeng,Jianming;  Hao,Wenhui;  Zhang,Xu;  Xu,Xiaoling;  Yu,Chundong;  Deng,Chu Xia;  Chen,Qiang
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Aib1  Ecm  Hedgehog  Mafb  Pdac  
Cisplatin prevents breast cancer metastasis through blocking early EMT and retards cancer growth together with paclitaxel Journal article
Theranostics, 2021,Volume: 11,Issue: 5,Page: 2442-2459
Authors:  Wang,Haitao;  Guo,Sen;  Kim,Seung Jin;  Shao,Fangyuan;  Kei Ho,Joshua Wing;  Wong,Kuan Un;  Miao,Zhengqiang;  Hao,Dapeng;  Zhao,Ming;  Xu,Jun;  Zeng,Jianming;  Wong,Koon Ho;  Di,Lijun;  Wong,Ada Hang Heng;  Xu,Xiaoling;  Deng,Chu Xia
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Cisplatin  Metastasis  Neoadjuvant Therapy  Paclitaxel  Tgfβ  
Oxygen-Evolving Manganese Ferrite Nanovesicles for Hypoxia-Responsive Drug Delivery and Enhanced Cancer Chemoimmunotherapy Journal article
Advanced Functional Materials, 2021
Authors:  Yang,Kuikun;  Yu,Guocan;  Tian,Rui;  Zhou,Zijian;  Deng,Hongzhang;  Li,Ling;  Yang,Zhen;  Zhang,Guofeng;  Liu,Dahai;  Wei,Jianwen;  Yue,Ludan;  Wang,Ruibing;  Chen,Xiaoyuan
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chemoimmunotherapy  drug delivery  hypoxia-responsive  self-assembly  
Characterization of BRCA1-deficient premalignant tissues and cancers identifies Plekha5 as a tumor metastasis suppressor Journal article
Nature Communications, 2020,Volume: 11,Issue: 1
Authors:  Liu,Jianlin;  Adhav,Ragini;  Miao,Kai;  Su,Sek Man;  Mo,Lihua;  Chan,Un In;  Zhang,Xin;  Xu,Jun;  Li,Jianjie;  Shu,Xiaodong;  Zeng,Jianming;  Zhang,Xu;  Lyu,Xueying;  Pardeshi,Lakhansing;  Tan,Kaeling;  Sun,Heng;  Wong,Koon Ho;  Deng,Chuxia;  Xu,Xiaoling
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A 7-methoxybicoumarin derivative selectively inhibits BRD4 BD2 for anti-melanoma therapy Journal article
International Journal of Biological Macromolecules, 2020,Volume: 164,Page: 3204-3220
Authors:  Yang,Guan Jun;  Wang,Wanhe;  Lei,Pui Man;  Leung,Chung Hang;  Ma,Dik Lung
Favorite |  | TC[WOS]:0 TC[Scopus]:0 | Submit date:2021/03/01
BRD4  Bromodomain domain  Cell metastasis and invasion  Histone acetylation  Melanoma  Protein–protein interaction  Virtual screening  
The role of FOXOs and autophagy in cancer and metastasis—Implications in therapeutic development Journal article
Medicinal Research Reviews, 2020,Volume: 40,Issue: 6,Page: 2089-2113
Authors:  Farhan,Mohd;  Silva,Marta;  Li,Shuai;  Yan,Fengxia;  Fang,Jiankang;  Peng,Tangming;  Hu,Jim;  Tsao,Ming Sound;  Little,Peter;  Zheng,Wenhua
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autophagy  cancer  FOXO proteins  metastasis  
Natural alkaloid 8-oxo-epiberberine inhibited TGF-β1-triggred epithelial-mesenchymal transition by interfering Smad3 Journal article
Toxicology and Applied Pharmacology, 2020,Volume: 404
Authors:  Liu,Xin;  Zhang,Yiying;  ZHOU,Guang Ju;  Hou,Ying;  Kong,Qi;  Lu,Jin Jian;  Zhang,Qingwen;  Chen,Xiuping
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8-oxo-epiberberine  Epithelial-mesenchymal Transition  Metastasis  Tgf-β1  
Role of FOXO Transcription Factors in Cancer Metabolism and Angiogenesis Journal article
Cells, 2020,Volume: 9,Issue: 7
Authors:  Farhan,Mohd;  Silva,Marta;  Xingan,Xing;  Huang,Yu;  Zheng,Wenhua
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angiogenesis  cancer  cancer metabolism  FOXOs  
Nuclear DLC1 exerts oncogenic function through association with FOXK1 for cooperative activation of MMP9 expression in melanoma Journal article
Oncogene, 2020,Volume: 39,Issue: 20,Page: 4061-4076
Authors:  Yang,Xintao;  Hu,Feng;  Liu,Jessica Aijia;  Yu,Shan;  Cheung,May Pui Lai;  Liu,Xuelai;  Ng,Irene Oi Lin;  Guan,Xin Yuan;  Wong,Kelvin K.W.;  Sharma,Rakesh;  Lung,Hong Lok;  Jiao,Yufei;  Lee,Leo Tsz On;  Cheung,Martin
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