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Panax notoginseng Saponins Modulate the Inflammatory Response and Improve IBD-Like Symptoms via TLR/NF- κ B and MAPK Signaling Pathways Journal article
American Journal of Chinese Medicine, 2021,Volume: 49,Issue: 4,Page: 925-939
Authors:  Luo, Hua;  Vong, Chi Teng;  Tan, Dechao;  Zhang, Jinming;  Yu, Hua;  Yang, Lin;  Zhang, Chen;  Luo, Chun;  Zhong, Zhangfeng;  Wang, Yitao
Favorite |  | TC[WOS]:0 TC[Scopus]:0 | Submit date:2021/09/13
Dextran Sulfate Sodium  Inflammatory Bowel Disease  Mapk  Nf- κ b Signaling Pathways  Panax Notoginseng Saponins  
A novel strategy for glioblastoma treatment by induction of noptosis, an NQO1-dependent necrosis Journal article
Free Radical Biology and Medicine, 2021,Volume: 166,Page: 104-115
Authors:  Zhong, Bingling;  Yu, Jie;  Hou, Ying;  Ai, Nana;  Ge, Wei;  Lu, Jin Jian;  Chen, Xiuping
Favorite |  | TC[WOS]:0 TC[Scopus]:0 | Submit date:2021/09/17
Glioblastoma  Jnk1/2  Noptosis  Nqo1  Tanshindiol b  
Development of dual inhibitors targeting pyruvate dehydrogenase kinases and human lactate dehydrogenase A: High-throughput virtual screening, synthesis and biological validation Journal article
European Journal of Medicinal Chemistry, 2020,Volume: 203
Authors:  Xiang,Sichuan;  Huang,Ding;  He,Qiaolin;  Li,Jie;  Tam,Kin Yip;  Zhang,Shao Lin;  He,Yun
Favorite |  | TC[WOS]:2 TC[Scopus]:2 | Submit date:2021/03/04
Cancer metabolism  Cancer proliferation  Dual inhibitor  Lactate dehydrogenase A  Pyruvate dehydrogenase kinase  
Conditional reprogramming: next generation cell culture Journal article
Acta Pharmaceutica Sinica B, 2020,Volume: 10,Issue: 8,Page: 1360-1381
Authors:  Wu,Xiaoxiao;  Wang,Shengpeng;  Li,Mingxing;  Li,Jing;  Shen,Jing;  Zhao,Yueshui;  Pang,Jun;  Wen,Qinglian;  Chen,Meijuan;  Wei,Bin;  Kaboli,Parham Jabbarzadeh;  Du,Fukuan;  Zhao,Qijie;  Cho,Chi Hin;  Wang,Yitao;  Xiao,Zhangang;  Wu,Xu
Favorite |  | TC[WOS]:11 TC[Scopus]:10 | Submit date:2021/03/02
3t3-j2 Fibroblast  Conditional Reprogramming  Rock  Senescence  Y-27632  
Current strategies for treating NSCLC: From biological mechanisms to clinical treatment Journal article
Cancers, 2020,Volume: 12,Issue: 6,Page: 1-24
Authors:  Li,Junnan;  Kwok,Hang Fai
Favorite |  | TC[WOS]:7 TC[Scopus]:8 | Submit date:2021/03/04
Combination targeted therapy  Drug resistance mechanism  EGFR mutation  Lung cancer  
Phanginin R induces cytoprotective autophagy via JNK/C-JUN signaling pathway in non-small cell lung cancer A549 cells Journal article
Anti-Cancer Agents in Medicinal Chemistry, 2020,Volume: 20,Issue: 8,Page: 982-988
Authors:  Zhang,Le Le;  Bao,Han;  Xu,Yu Lian;  Jiang,Xiao Ming;  Li,Wei;  Zou,Liang;  Lin,Li Gen;  Lu,Jin Jian
Favorite |  | TC[WOS]:1 TC[Scopus]:2 | Submit date:2021/03/01
Anti-cancer  Autophagy  C-jun  Jnk  Non-small Cell Lung Cancer  Phanginin r  
Cryptotanshinone from Salvia miltiorrhiza Bunge (Danshen) inhibited inflammatory responses via TLR4/MyD88 signaling pathway Journal article
Chinese Medicine (United Kingdom), 2020,Volume: 15,Issue: 1
Authors:  Li, Xin Xing;  Zheng, Xiaoting;  Liu, Zhenjie;  Xu, Qiongming;  Tang, Hongzhen;  Feng, Jianfang;  Yang, Shilin;  Vong, Chi Teng;  Gao, Hongwei;  Wang, Yitao
Favorite |  | TC[WOS]:6 TC[Scopus]:5 | Submit date:2021/09/13
Anti-inflammation  Cryptotanshinone  Nrf2  Pi3k/akt  Tlr4-myd88  
3-O-acetylrubianol C (3AR-C) induces RIPK1-dependent programmed cell death by selective inhibition of IKKβ Journal article
FASEB Journal, 2020,Volume: 34,Issue: 3,Page: 4369-4383
Authors:  Kang,Kidong;  Quan,Khong Trong;  Byun,Hee Sun;  Lee,So Ra;  Piao,Xuezhe;  Ju,Eunjin;  Park,Kyeong Ah;  Sohn,Kyung Cheol;  Shen,Han Ming;  Na,Min Kyun;  Hur,Gang Min
Favorite |  | TC[WOS]:1 TC[Scopus]:1 | Submit date:2021/03/02
3AR-C  apoptosis  IKKβ  necroptosis  phosphorylation  RIPK1  TNF  
Inhibitory activity of a scorpion defensin BmKDfsin3 against hepatitis C virus Journal article
Antibiotics, 2020,Volume: 9,Issue: 1
Authors:  Cheng,Yuting;  Sun,Fang;  Li,Songryong;  Gao,Minjun;  Wang,Luyao;  Sarhan,Moustafa;  Abdel-Rahman,Mohamed A.;  Li,Wenxin;  Kwok,Hang Fai;  Wu,Yingliang;  Cao,Zhijian
Favorite |  | TC[WOS]:5 TC[Scopus]:6 | Submit date:2021/03/04
Hepatitis C virus (HCV)  P38  Scorpion defensin  
Protective mechanism of artemisinin on rat bone marrow-derived mesenchymal stem cells against apoptosis induced by hydrogen peroxide via activation of c-Raf-Erk1/2-p90rsk-CREB pathway Journal article
Stem Cell Research and Therapy, 2019,Volume: 10,Issue: 1
Authors:  Fang,Jiankang;  Zhao,Xia;  Li,Shuai;  Xing,Xingan;  Wang,Haitao;  Lazarovici,Philip;  Zheng,Wenhua
Favorite |  | TC[WOS]:18 TC[Scopus]:18 | Submit date:2021/03/04
Apoptosis  Artemisinin  Bone marrow mesenchymal stem cells  CREB  Erk1/2  p90rsk  Phosphorylation  Protection  Raf  ROS