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Recent developments of human monocarboxylate transporter (hMCT) inhibitors as anticancer agents Journal article
Drug Discovery Today, 2021
Authors:  Wu,Puhua;  Zhou,Yan;  Guo,Yizhen;  Zhang,Shao Lin;  Tam,Kin Yip
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In Vivo Screening of Xanthones from Garcinia oligantha Identified Oliganthin H as a Novel Natural Inhibitor of Convulsions Journal article
Journal of Natural Products, 2020,Volume: 83,Issue: 12,Page: 3706-3716
Authors:  Gong,Guiyi;  Chen,Hanbin;  Kam,Hiotong;  Chan,Ging;  Tang,Yue Xun;  Wu,Man;  Tan,Hongsheng;  Tse,Yu Chung;  Xu,Hong Xi;  Lee,Simon Ming Yuen
Favorite |  | TC[WOS]:1 TC[Scopus]:1 | Submit date:2021/03/01
Conditional reprogramming: next generation cell culture Journal article
Acta Pharmaceutica Sinica B, 2020,Volume: 10,Issue: 8,Page: 1360-1381
Authors:  Wu,Xiaoxiao;  Wang,Shengpeng;  Li,Mingxing;  Li,Jing;  Shen,Jing;  Zhao,Yueshui;  Pang,Jun;  Wen,Qinglian;  Chen,Meijuan;  Wei,Bin;  Kaboli,Parham Jabbarzadeh;  Du,Fukuan;  Zhao,Qijie;  Cho,Chi Hin;  Wang,Yitao;  Xiao,Zhangang;  Wu,Xu
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3t3-j2 Fibroblast  Conditional Reprogramming  Rock  Senescence  Y-27632  
Enhanced Antimicrobial Activity of N-Terminal Derivatives of a Novel Brevinin-1 Peptide from the Skin Secretion of Odorrana schmackeri Journal article
Toxins, 2020,Volume: 12,Issue: 8
Authors:  Zhou,Xiaowei;  Liu,Yue;  Gao,Yitian;  Wang,Yuanxing;  Xia,Qiang;  Zhong,Ruimin;  Ma,Chengbang;  Zhou,Mei;  Xi,Xinping;  Shaw,Chris;  Chen,Tianbao;  Wu,Di;  Kwok,Hang Fai;  Wang,Lei
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Antimicrobial activity  Skin-derived peptides  Stability  Waxworm model  
Organoids and Microphysiological Systems: New Tools for Ophthalmic Drug Discovery Journal article
Frontiers in Pharmacology, 2020,Volume: 11
Authors:  Bai,Jing;  Wang,Chunming
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3d Tissue Constructs  Microphysiological System  Ocular  Organ-on-a-chip  Organoid  
The design and development of covalent protein-protein interaction inhibitors for cancer treatment Journal article
Journal of Hematology and Oncology, 2020,Volume: 13,Issue: 1
Authors:  Cheng,Sha Sha;  Yang,Guan Jun;  Wang,Wanhe;  Leung,Chung Hang;  Ma,Dik Lung
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Cancer therapy  Covalent inhibitors  Protein-protein interaction  
In Vitro and MD Simulation Study to Explore Physicochemical Parameters for Antibacterial Peptide to Become Potent Anticancer Peptide Journal article
Molecular Therapy - Oncolytics, 2020,Volume: 16,Page: 7-19
Authors:  Ma,Rui;  Wong,Sin Wa;  Ge,Lilin;  Shaw,Chris;  Siu,Shirley W.I.;  Kwok,Hang Fai
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angiogenesis  anticancer peptides  antimicrobial peptides  apoptosis  drug discovery and development  molecular dynamics  targeted therapy  
The development of small-molecule inhibitors targeting CD47 Journal article
Drug Discovery Today, 2020
Authors:  Yu,Wei Bang;  Ye,Zi Han;  Chen,Xiuping;  Shi,Jia Jie;  Lu,Jin Jian
Favorite |  | TC[WOS]:1 TC[Scopus]:0 | Submit date:2021/03/01
Transcriptome analysis of peripheral whole blood identifies crucial lncRNAs implicated in childhood asthma Journal article
BMC Medical Genomics, 2020,Volume: 13,Issue: 1
Authors:  Zheng P.;  Huang C.;  Leng D.;  Sun B.;  Zhang X.D.
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Childhood Asthma  Deep Rna-sequencing  Long Non-coding Rnas  Transcriptome  
Small molecule IVQ, as a prodrug of gluconeogenesis inhibitor QVO, efficiently ameliorates glucose homeostasis in type 2 diabetic mice Journal article
ACTA PHARMACOLOGICA SINICA, 2019,Volume: 40,Issue: 9,Page: 1193-1204
Authors:  Ting-ting Zhou;  Tong Zhao;  Fei Ma;  Yi-nan Zhang;  Jing Jiang;  Yuan Ruan;  Qiu-ying Yan;  Gai-hong Wang;  Jin Ren;  Xiao-wei Guan;  Jun Guo;  Yong-hua Zhao;  Ji-ming Ye;  Li-hong Hu;  Jing Chen;  Xu Shen
Favorite |  | TC[WOS]:3 TC[Scopus]:3 | Submit date:2020/04/14
Type 2 Diabetes Mellitus  Hepatic Gluconeogenesis  Ampk Signaling Pathway  (e)-3-(2-(Quinoline-4-yl)Vinyl)-1h-indol-6-ol (Qvo)  4-[2-(1h-indol-3-yl)Vinyl]Quinoline (Ivq)  Prodrug