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9R, the cholinesterase and amyloid beta aggregation dual inhibitor, as a multifunctional agent to improve cognitive deficit and neuropathology in the triple-transgenic Alzheimer's disease mouse model Journal article
Neuropharmacology, 2020,Volume: 181
Authors:  Ju,Yaojun;  Tam,Kin Yip
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Alzheimer's disease  Amyloid beta  Cholinesterase  Dual inhibition  Multifunction  
An Isoquinolinium Dual Inhibitor of Cholinesterases and Amyloid β Aggregation Mitigates Neuropathological Changes in a Triple-Transgenic Mouse Model of Alzheimer's Disease Journal article
ACS Chemical Neuroscience, 2020,Volume: 11,Issue: 20,Page: 3346-3357
Authors:  Ju,Yaojun;  Chakravarty,Harapriya;  Tam,Kin Yip
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Alzheimer's disease  amyloid beta  cholinesterase  dual inhibition  
Dual targeting of cholinesterase and amyloid beta with pyridinium/isoquinolium derivatives Journal article
Drug Development Research, 2020,Volume: 81,Issue: 2,Page: 242-255
Authors:  Chakravarty,Harapriya;  Ju,Yaojun;  Chen,Wen Hua;  Tam,Kin Y.
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acetylcholinesterase  Alzheimer's disease  amyloid beta  butyrylcholinesterase  dual target inhibitor  isoquinolinium  pyridinium  
Fish oil protects the blood-brain barrier integrity in a mouse model of Alzheimer's disease Journal article
Chinese Medicine (United Kingdom), 2020,Volume: 15,Issue: 1
Authors:  Xie,Youna;  Yan,Lingli;  Zeng,Haitao;  Chen,Weineng;  Lu,Jia Hong;  Wan,Jian Bo;  Su,Huanxing;  Yao,Xiaoli
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Amyloid beta  Aβ-degrading enzymes  Neuroinflammation  NF-κB  Omega-3 polyunsaturated fatty acids  
Omega-3 polyunsaturated fatty acids promote brain-to-blood clearance of β-Amyloid in a mouse model with Alzheimer's disease Journal article
Brain, Behavior, and Immunity, 2020,Volume: 85,Page: 35-45
Authors:  Yan,Lingli;  Xie,Youna;  Satyanarayanan,Senthil Kumaran;  Zeng,Haitao;  Liu,Qiang;  Huang,Miaodan;  Ma,Yuemeng;  Wan,Jian Bo;  Yao,Xiaoli;  Su,Kuan Pin;  Su,Huanxing
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Alzheimer's disease  beta-Amyloid  Low-density lipoprotein receptor-related protein 1  Neuroinflammation  Omega-3 polyunsaturated fatty acids  
A small molecule transcription factor EB activator ameliorates beta-amyloid precursor protein and Tau pathology in Alzheimer's disease models Journal article
Aging Cell, 2020,Volume: 19,Issue: 2
Authors:  Song,Ju Xian;  Malampati,Sandeep;  Zeng,Yu;  Durairajan,Siva Sundara Kumar;  Yang,Chuan Bin;  Tong,Benjamin Chun Kit;  Iyaswamy,Ashok;  Shang,Wen Bin;  Sreenivasmurthy,Sravan Gopalkrishnashetty;  Zhu,Zhou;  Cheung,King Ho;  Lu,Jia Hong;  Tang,Chunzhi;  Xu,Nenggui;  Li,Min
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Alzheimer's disease  beta-amyloid  curcumin analog C1  MAPT/Tau  TFEB  
Artemisinin improved neuronal functions in Alzheimer's disease animal model 3xtg mice and neuronal cells via stimulating the ERK/CREB signaling pathway Journal article
Aging and Disease, 2020,Volume: 11,Issue: 4,Page: 801-819
Authors:  Zhao,Xia;  Li,Shuai;  Gaur,Uma;  Zheng,Wenhua
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3×Tg mice  Alzheimer's disease  Amyloid beta  Artemisinin  Cognitive behavior  SH-SY5Ycells  
NRBF2 is a RAB7 effector required for autophagosome maturation and mediates the association of APP-CTFs with active form of RAB7 for degradation Journal article
Autophagy, 2020
Authors:  Cai,Cui Zan;  Yang,Chuanbin;  Zhuang,Xu Xu;  Yuan,Ning Ning;  Wu,Ming Yue;  Tan,Jie Qiong;  Song,Ju Xian;  Cheung,King Ho;  Su,Huanxing;  Wang,Yi Tao;  Tang,Bei Sha;  Behrends,Christian;  Durairajan,Siva Sundara Kumar;  Yue,Zhenyu;  Li,Min;  Lu,Jia Hong
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Amaturation  Autophagy  CCZ1-MON1A  NRBF2  PI3KC3/VPS34  RAB7  trafficking  
The use of back propagation neural networks and 18F-Florbetapir PET for early detection of Alzheimer's disease using Alzheimer's Disease Neuroimaging Initiative database Journal article
PLoS ONE, 2019,Volume: 14,Issue: 12
Authors:  Ozsahin,Ilker;  Sekeroglu,Boran;  Mok,Greta S.P.
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Autophagy protein NRBF2 has reduced expression in Alzheimer's brains and modulates memory and amyloid-beta homeostasis in mice Journal article
Molecular Neurodegeneration, 2019,Volume: 14,Issue: 1
Authors:  Lachance,Véronik;  Wang,Qian;  Sweet,Eric;  Choi,Insup;  Cai,Cui Zan;  Zhuang,Xu Xu;  Zhang,Yuanxi;  Jiang,Jessica Li;  Blitzer,Robert D.;  Bozdagi-Gunal,Ozlem;  Zhang,Bin;  Lu,Jia Hong;  Yue,Zhenyu
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