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A 7-methoxybicoumarin derivative selectively inhibits BRD4 BD2 for anti-melanoma therapy Journal article
International Journal of Biological Macromolecules, 2020,Volume: 164,Page: 3204-3220
Authors:  Yang,Guan Jun;  Wang,Wanhe;  Lei,Pui Man;  Leung,Chung Hang;  Ma,Dik Lung
Favorite |  | TC[WOS]:0 TC[Scopus]:0 | Submit date:2021/03/01
BRD4  Bromodomain domain  Cell metastasis and invasion  Histone acetylation  Melanoma  Protein–protein interaction  Virtual screening  
The role of autophagy in liver cancer: Crosstalk in signaling pathways and potential therapeutic targets Journal article
Pharmaceuticals, 2020,Volume: 13,Issue: 12,Page: 1-27
Authors:  Cui,Jianzhou;  Shen,Han Ming;  Lim,Lina Hsiu Kim
Favorite |  | TC[WOS]:0 TC[Scopus]:0 | Submit date:2021/03/02
AMPK  Autophagy  HCC  MAPK  MTOR  P53  ULK1  
Targeting RNA helicase DHX33 blocks Ras-driven lung tumorigenesis in vivo Journal article
Cancer Science, 2020,Volume: 111,Issue: 10,Page: 3564-3575
Authors:  Wang,Xingshun;  Feng,Weimin;  Peng,Cheng;  Chen,Shiyun;  Ji,Hongbin;  Zhong,Hanbing;  Ge,Wei;  Zhang,Yandong
Favorite |  | TC[WOS]:0 TC[Scopus]:1 | Submit date:2021/03/02
DHX33  lung cancer  oncogene  Ras  RNA helicase  
Stagewise keratinocyte differentiation from human embryonic stem cells by defined signal transduction modulators Journal article
International Journal of Biological Sciences, 2020,Volume: 16,Issue: 8,Page: 1450-1462
Authors:  Zhong,Hui;  Ren,Zhili;  Wang,Xiaoyan;  Miao,Kai;  Ni,Wenjun;  Meng,Ya;  Lu,Ligong;  Wang,Chunming;  Liu,Weiwei;  Deng,Chu Xia;  Xu,Ren He;  Chen,Guokai
Favorite |  | TC[WOS]:0 TC[Scopus]:0 | Submit date:2020/09/16
Defined Factors  Human Embryonic Stem Cells  Keratinocyte Differentiation  
Endogenous IGF Signaling Directs Heterogeneous Mesoderm Differentiation in Human Embryonic Stem Cells Journal article
Cell Reports, 2019,Volume: 29,Issue: 11,Page: 3374-3384.e5
Authors:  Yang,Yang;  Ren,Zhili;  Xu,Faxiang;  Meng,Ya;  Zhang,Yumeng;  Ai,Nana;  Long,Yan;  Fok,Hio Ian;  Deng,Chunhao;  Zhao,Xianyang;  Huang,Liancheng;  Zhao,Qi;  Wang,Jiaxian;  Liu,Weiwei;  Ge,Wei;  Chen,Guokai
Favorite |  | TC[WOS]:2 TC[Scopus]:2 | Submit date:2021/03/02
Cardiomyocyte  Casein Kinase Ii  Heterogeneity  Human Embryonic Stem Cells  Igf  Insulin  Mesoderm  Pi3k  Temporal Regulation  Wnt  
Rmrp Mutation Disrupts Chondrogenesis and Bone Ossification in Zebrafish Model of Cartilage-Hair Hypoplasia via Enhanced Wnt/β-Catenin Signaling Journal article
Journal of Bone and Mineral Research, 2019,Volume: 34,Issue: 11,Page: 2101-2116
Authors:  Sun,Xianding;  Zhang,Ruobin;  Liu,Mi;  Chen,Hangang;  Chen,Liang;  Luo,Fengtao;  Zhang,Dali;  Huang,Junlan;  Li,Fangfang;  Ni,Zhenhong;  Qi,Huabing;  Su,Nan;  Jin,Min;  Yang,Jing;  Tan,Qiaoyan;  Du,Xiaolan;  Chen,Bo;  Huang,Haiyang;  Chen,Shuai;  Yin,Liangjun;  Xu,Xiaoling;  Deng,Chuxia;  Luo,Lingfei;  Xie,Yangli;  Chen,Lin
Favorite |  | TC[WOS]:4 TC[Scopus]:4 | Submit date:2020/09/16
Cartilage-hair Hypoplasia  Rmrp  Skeletal Development  Wnt/β-catenin  Zebrafish  
Elevated Exogenous Pyruvate Potentiates Mesodermal Differentiation through Metabolic Modulation and AMPK/mTOR Pathway in Human Embryonic Stem Cells Journal article
STEM CELL REPORTS, 2019,Volume: 13,Issue: 2,Page: 338-351
Authors:  Chengcheng Song;  Faxiang Xu;  Zhili Ren;  Yumeng Zhang;  Ya Meng;  Yiqi Yang;  Shreyas Lingadahalli;  Edwin Cheung;  Gang Li;  Weiwei Liu;  Jianbo Wan;  Yang Zhao;  Guokai Chen
Favorite |  | TC[WOS]:5 TC[Scopus]:6 | Submit date:2020/04/22
Hescs  Pyruvate  Bmp4  Glycolysis  Tca Cycle  Ampk  Wnt  Metabolism  Mesoderm  Differentiation  
Reduced camptothecin sensitivity of estrogen receptor-positive human breast cancer cells following exposure to di(2-ethylhexyl)phthalate (DEHP) is associated with DNA methylation changes Journal article
Environmental Toxicology, 2019,Volume: 34,Issue: 4,Page: 401-414
Authors:  Chou,Chon Kit;  Huang,Hurng Wern;  Yang,Chun Feng;  Dahms,Hans Uwe;  Liang,Shih Shin;  Wang,Tsu Nai;  Kuo,Po Lin;  Hsi,Edward;  Tsai,Eing Mei;  Chiu,Chien Chih
Favorite |  | TC[WOS]:3 TC[Scopus]:4 | Submit date:2021/03/02
Camptothecin  Di(2-ethylhexyl)Phthalate (Dehp)  Dna Methylation  Erα-dependent Manner  Human Breast Cancer  Wnt/β-catenin Signaling  
GSK3-activated STAT5 regulates expression of SFRPs to modulate adipogenesis Journal article
FASEB JOURNAL, 2018,Volume: 32,Issue: 9,Page: 4714-4726
Authors:  Wang, Li;  Wang, Yuan;  Meng, Yuan;  Zhang, Chao;  Di, Lijun
Favorite |  | TC[WOS]:14 TC[Scopus]:11 | Submit date:2018/10/30
Adipocyte Differentiation  Gsk3  Wnt Pathway  
DJ-1 promotes colorectal cancer progression through activating PLAGL2/Wnt/BMP4 axis Journal article
CELL DEATH & DISEASE, 2018,Volume: 9
Authors:  Zhou, Jing;  Liu, Hao;  Zhang, Lian;  Liu, Xin;  Zhang, Chundong;  Wang, Yitao;  He, Qing;  Zhang, Ying;  Li, Yi;  Chen, Quanmei;  Zhang, Lu;  Wang, Kui;  Bu, Youquan;  Lei, Yunlong
Favorite |  | TC[WOS]:24 TC[Scopus]:23 | Submit date:2018/11/01