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Shikonin promotes ubiquitination and degradation of cIAP1/2-mediated apoptosis and necrosis in triple negative breast cancer cells Journal article
Chinese Medicine (United Kingdom), 2021,Volume: 16,Issue: 1
Authors:  Wang,Anqi;  Liu,Jiayu;  Yang,Yuhan;  Chen,Zhejie;  Gao,Caifang;  Wang,Zhanguo;  Fu,Chaomei;  Zou,Liang;  Wang,Shengpeng
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Apoptosis  Breast Cancer  Necrosis  Shikonin  Ubiquitination  
Silica nanoparticles inhibiting the differentiation of round spermatid and chromatin remodeling of haploid period via MIWI in mice Journal article
Environmental Pollution, 2021,Volume: 284
Authors:  Liu, Jianhui;  Li, Xiangyang;  Zhou, Guiqing;  Zhang, Yue;  Sang, Yujian;  Wang, Ji;  Li, Yanbo;  Ge, Wei;  Sun, Zhiwei;  Zhou, Xianqing
Favorite |  | TC[WOS]:0 TC[Scopus]:0 | Submit date:2021/09/17
Chromatin Remodeling  Mice  Miwi  Silica Nanoparticles  Spermatid Differentiation  Spermatogenesis  
A Destiny for Degradation: Interplay between Cullin-RING E3 Ligases and Autophagy Journal article
Trends in Cell Biology, 2021
Authors:  Lu,Guang;  Wang,Liming;  Zhou,Jing;  Liu,Wei;  Shen,Han Ming
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autophagy  cancer  cullin-RING E3 ligases  MTORC1  neddylation  ubiquitination  
Discovery of a novel EGFR ligand DPBA that degrades EGFR and suppresses EGFR-positive NSCLC growth Journal article
Signal Transduction and Targeted Therapy, 2020,Volume: 5,Issue: 1
Authors:  Yao,Nan;  Wang,Chen Ran;  Liu,Ming Qun;  Li,Ying Jie;  Chen,Wei Min;  Li,Zheng Qiu;  Qi,Qi;  Lu,Jin Jian;  Fan,Chun Lin;  Chen,Min Feng;  Qi,Ming;  Li,Xiao Bo;  Hong,Jian;  Zhang,Dong Mei;  Ye,Wen Cai
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Post-translational modifications of PRC2: signals directing its activity Journal article
Epigenetics and Chromatin, 2020,Volume: 13,Issue: 1
Authors:  Yang,Yiqi;  Li,Gang
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Cgis  Cis Chromatin Features  Facultative Subunits  Methylation  Phosphorylation  Prc2  Ptms  Ubiquitination  
Acetyltanshinone IIA is more potent than lapatinib in inhibiting cell growth and degrading HER2 protein in drug-resistant HER2-positive breast cancer cells Journal article
Cancer Letters, 2020,Volume: 490,Page: 1-11
Authors:  Huang,Bin;  Yip,Wai Kien;  Wei,Na;  Luo,Kathy Qian
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Acetyltanshinone IIA  Drug resistance  HER2 degradation  HER2-positive breast cancer  
LncRNA UCA1 maintains the low-tumorigenic and nonmetastatic status by stabilizing E-cadherin in primary prostate cancer cells Journal article
Molecular Carcinogenesis, 2020,Volume: 59,Issue: 10,Page: 1174-1187
Authors:  Zhao,Xian;  Wang,Yanli;  He,Jianfeng;  Deng,Rong;  Huang,Xiaojun;  Guo,Yanmin;  Li,Lian;  Xie,Ruiyu;  Yu,Jianxiu
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E-cadherin  LncRNA UCA1  MDM2  miR-296-3p  primary prostate cancer cells  
Machado-Joseph Deubiquitinases: From Cellular Functions to Potential Therapy Targets Journal article
Frontiers in Pharmacology, 2020,Volume: 11
Authors:  Zeng,Chenming;  Zhao,Chenxi;  Ge,Fujing;  Li,Yuekang;  Cao,Ji;  Ying,Meidan;  Lu,Jinjian;  He,Qiaojun;  Yang,Bo;  Dai,Xiaoyang;  Zhu,Hong
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Cancer Therapy  Cellular Functions  Deubiquitinase  Machado-joseph Domain-containing Proteases  Mjd Disease  
PHLDA1 promotes microglia-mediated neuroinflammation via regulating K63-linked ubiquitination of TRAF6 Journal article
Brain, Behavior, and Immunity, 2020,Volume: 88,Page: 640-653
Authors:  Han,Chaojun;  Yan,Pengju;  He,Tao;  Cheng,Junjie;  Zheng,Wenhua;  Zheng,Long Tai;  Zhen,Xuechu
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Dopaminergic neuron  Microglia  Neuroinflammation  NF-κB  PHLDA1  TRAF6  Ubiquitination  
Post-translational modification of KRAS: potential targets for cancer therapy Journal article
Acta Pharmacologica Sinica, 2020
Authors:  Wang,Wei hua;  Yuan,Tao;  Qian,Mei jia;  Yan,Fang jie;  Yang,Liu;  He,Qiao jun;  Yang,Bo;  Lu,Jin jian;  Zhu,Hong
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Acetylation  Cancer Therapy  Kras  Nitrosylation  Oncogene  Palmitoylation  Phosphorylation  Post-translational Modification  Postprenylation  Prenylation  Sumoylation  Ubiquitination