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Ubiquitination Regulators Discovered by Virtual Screening for the Treatment of Cancer Journal article
Frontiers in Cell and Developmental Biology, 2021,Volume: 9
Authors:  Song, Ying Qi;  Wu, Chun;  Wu, Ke Jia;  Han, Quan Bin;  Miao, Xiang Min;  Ma, Dik Lung;  Leung, Chung Hang
Favorite |  | TC[WOS]:0 TC[Scopus]:0 | Submit date:2021/12/07
cancer  drug discovery  treatment  ubiquitination regulator  virtual screening  
A Destiny for Degradation: Interplay between Cullin-RING E3 Ligases and Autophagy Journal article
Trends in Cell Biology, 2021
Authors:  Lu,Guang;  Wang,Liming;  Zhou,Jing;  Liu,Wei;  Shen,Han Ming
Favorite |  | TC[WOS]:2 TC[Scopus]:4 | Submit date:2021/03/02
autophagy  cancer  cullin-RING E3 ligases  MTORC1  neddylation  ubiquitination  
Oxyphylla a promotes degradation of α-synuclein for neuroprotection via activation of immunoproteasome Journal article
Aging and Disease, 2020,Volume: 11,Issue: 3,Page: 559-574
Authors:  Zhou,Hefeng;  Li,Shengnan;  Li,Chuwen;  Yang,Xuanjun;  Li,Haitao;  Zhong,Hanbing;  Lu,Jia Hong;  Lee,Simon Ming Yuen
Favorite |  | TC[WOS]:4 TC[Scopus]:5 | Submit date:2021/03/01
Degradation  Neuroprotection  Parkinson's Disease  Proteasome  Α-synuclein  
Organism dual RNA-seq reveals the importance of BarA/UvrY in Vibrio parahaemolyticus virulence Journal article
FASEB Journal, 2020,Volume: 34,Issue: 6,Page: 7561-7577
Authors:  Zhang W.;  Xie R.;  Zhang X.D.;  Lee L.T.O.;  Zhang H.;  Yang M.;  Peng B.;  Zheng J.
Adobe PDF | Favorite |  | TC[WOS]:1 TC[Scopus]:1 | Submit date:2021/03/03
Bara  C. Elegans  Organism Dual Rna-seq  Uvry  V. Parahaemolyticus  Virulence Factor  
Natural alkaloid harmine promotes degradation of alpha-synuclein via PKA-mediated ubiquitin-proteasome system activation Journal article
Phytomedicine, 2019,Volume: 61
Authors:  Cai,Cui Zan;  Zhou,He Feng;  Yuan,Ning Ning;  Wu,Ming Yue;  Lee,Simon Ming Yuen;  Ren,Jiao Yan;  Su,Huan Xing;  Lu,Jin Jian;  Chen,Xiu Ping;  Li,Min;  Tan,Jie Qiong;  Lu,Jia Hong
Favorite |  | TC[WOS]:14 TC[Scopus]:14 | Submit date:2021/03/01
-synuclein  Harmine  Parkinson's Disease  Protein Kinase a  Ubiquitin-proteasome System  
Canthin-6-One Accelerates Alpha-Synuclein Degradation by Enhancing UPS Activity: Drug Target Identification by CRISPR-Cas9 Whole Genome-Wide Screening Technology Journal article
FRONTIERS IN PHARMACOLOGY, 2019,Volume: 10
Authors:  Ning-Ning Yuan;  Cui-Zan Cai;  Ming-Yue Wu;  Qi Zhu;  HuanXing Su;  Min Li;  JiaoYan Ren;  Jie-Qiong Tan;  Jia-Hong Lu
Favorite |  | TC[WOS]:8 TC[Scopus]:9 | Submit date:2020/04/14
Canthin-6-one  Parkinson’s Disease  Alpha-synuclein  Ubiquitin-proteasome-system  Crispr/cas9  Rpn2/psmd1  Pka  
Downregulation of Cyclin B1 mediates nagilactone E-induced G2 phase cell cycle arrest in non-small cell lung cancer cells Journal article
EUROPEAN JOURNAL OF PHARMACOLOGY, 2018,Volume: 830,Page: 17-25
Authors:  Zhang, Le-Le;  Feng, Zhe-Ling;  Su, Min-Xia;  Jiang, Xiao-Ming;  Chen, Xiuping;  Wang, Yitao;  Li, Ao;  Lin, Li-Gen;  Lu, Jin-Jian
View | Adobe PDF | Favorite |  | TC[WOS]:23 TC[Scopus]:21 | Submit date:2018/10/30
Nagilactone e  Non-small Cell Lung Cancer  Cyclin B1  Cell Cycle  Apoptosis  
Physalin B induces cell cycle arrest and triggers apoptosis in breast cancer cells through modulating p53-dependent apoptotic pathway Journal article
BIOMEDICINE & PHARMACOTHERAPY, 2018,Volume: 101,Page: 334-341
Authors:  Wang, Anqi;  Wang, Shengpeng;  Zhou, Fayang;  Li, Peng;  Wang, Yitao;  Gan, Lishe;  Lin, Ligen
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Physalin b  Breast Cancer  Cell Cycle  Apoptosis  P53  Akt  
Osimertinib (AZD9291) decreases programmed death ligand-1 in EGFR-mutated non-small cell lung cancer cells Journal article
ACTA PHARMACOLOGICA SINICA, 2017,Volume: 38,Issue: 11,Page: 1512-1520
Authors:  Jiang, Xiao-Ming;  Xu, Yu-Lian;  Huang, Mu-Yang;  Zhang, Le-Le;  Su, Min-Xia;  Chen, Xiuping;  Lu, Jin-Jian
Favorite |  | TC[WOS]:32 TC[Scopus]:31 | Submit date:2018/10/30
Non-small Cell Lung Cancer  Egfr  Osimertinib  Pd-l1  Ubiquitin-proteasome System  Mg-132  Bortezomib  Gsk3 Beta  Licl  
Schisandrin B reverses doxorubicin resistance through inhibiting P-glycoprotein and promoting proteasome-mediated degradation of survivin Journal article
SCIENTIFIC REPORTS, 2017,Volume: 7
Authors:  Wang, Shengpeng;  Wang, Anqi;  Shao, Min;  Lin, Ligen;  Li, Peng;  Wang, Yitao
View | Adobe PDF | Favorite |  | TC[WOS]:15 TC[Scopus]:17 | Submit date:2018/10/30