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Pharmacological inhibition of KDM5A for cancer treatment Journal article
European Journal of Medicinal Chemistry, 2021,Volume: 226
Authors:  Yang, Guan Jun;  Wu, Jia;  Miao, Liang;  Zhu, Ming Hui;  Zhou, Qian Jin;  Lu, Xin Jiang;  Lu, Jian Fei;  Leung, Chung Hang;  Ma, Dik Lung;  Chen, Jiong
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Cancer therapy  Drug resistance  Histone methylation  Lysine-specific demethylase 5A  Screening methods  
Shikonin promotes ubiquitination and degradation of cIAP1/2-mediated apoptosis and necrosis in triple negative breast cancer cells Journal article
Chinese Medicine (United Kingdom), 2021,Volume: 16,Issue: 1
Authors:  Wang,Anqi;  Liu,Jiayu;  Yang,Yuhan;  Chen,Zhejie;  Gao,Caifang;  Wang,Zhanguo;  Fu,Chaomei;  Zou,Liang;  Wang,Shengpeng
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Apoptosis  Breast Cancer  Necrosis  Shikonin  Ubiquitination  
Targeting B7-H3 via chimeric antigen receptor T cells and bispecific killer cell engagers augments antitumor response of cytotoxic lymphocytes Journal article
Journal of Hematology and Oncology, 2021,Volume: 14,Issue: 1
Authors:  Liu,Jie;  Yang,Shuo;  Cao,Bihui;  Zhou,Guangyu;  Zhang,Fengjuan;  Wang,Yuan;  Wang,Rixin;  Zhu,Lipeng;  Meng,Ya;  Hu,Cong;  Liang,Hui;  Lin,Xu;  Zhu,Kangshun;  Chen,Guokai;  Luo,Kathy Qian;  Di,Lijun;  Zhao,Qi
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B7-h3  Bike  Bispecific Antibody  Car t  Chimeric Antigen Receptor  Non-small Cell Lung Cancer  Pd-l1  
A nanounit strategy reverses immune suppression of exosomal PD-L1 and is associated with enhanced ferroptosis Journal article
Nature Communications, 2021,Volume: 12,Issue: 1
Authors:  Wang, Guohao;  Xie, Lisi;  Li, Bei;  Sang, Wei;  Yan, Jie;  Li, Jie;  Tian, Hao;  Li, Wenxi;  Zhang, Zhan;  Tian, Ye;  Dai, Yunlu
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Drug resistance of targeted therapy for advanced non-small cell lung cancer harbored EGFR mutation: from mechanism analysis to clinical strategy Journal article
Journal of Cancer Research and Clinical Oncology, 2021,Volume: 147,Issue: 12,Page: 3653-3664
Authors:  Zhao, Yuxin;  Wang, Haiyong;  He, Chengwei
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Drug resistance  Epidermal growth factor receptor-tyrosine kinase inhibitor  Non-small cell lung cancer  Targeted therapy  
A TNFR2 antibody by countering immunosuppression cooperates with HMGN1 and R848 immune stimulants to inhibit murine colon cancer Journal article
International Immunopharmacology, 2021,Volume: 101
Authors:  Jiang, Mengmeng;  Liu, Jia;  Yang, De;  Tross, Debra;  Li, Ping;  Chen, Fengyang;  Alam, Md Masud;  Faustman, Denise L.;  Oppenheim, Joost J.;  Chen, Xin
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Antitumor  CD4+Foxp3+ regulatory T cells (Tregs)  HMGN1 and R848  Immunotherapy  TNFR2  
The Wnt signaling pathway in tumorigenesis, pharmacological targets, and drug development for cancer therapy Journal article
Biomarker Research, 2021,Volume: 9,Issue: 1
Authors:  Wang, Zhuo;  Zhao, Tingting;  Zhang, Shihui;  Wang, Junkai;  Chen, Yunyun;  Zhao, Hongzhou;  Yang, Yaxin;  Shi, Songlin;  Chen, Qiang;  Liu, Kuancan
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beta-catenin  Drug development  Epigenetic modification  Tumor microenvironment  Wnt signaling  
Differential role of TNFR1 and TNFR2 in the development of imiquimod-induced mouse psoriasis Journal article
Journal of Leukocyte Biology, 2021,Volume: 110,Issue: 6,Page: 1047-1055
Authors:  Chen, Shaokui;  Lin, Zibei;  Xi, Long;  Zheng, Ying;  Zhou, Qiong;  Chen, Xin
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CD4+Foxp3+ regulatory T cells  psoriasis  TNF  TNFR1  TNFR2  
Anti-angiogenesis and anti-metastasis effects of Polyphyllin VII on Hepatocellular carcinoma cells in vitro and in vivo Journal article
Chinese Medicine (United Kingdom), 2021,Volume: 16,Issue: 1
Authors:  Zhang, Chao;  Li, Qingrui;  Qin, Guozheng;  Zhang, Yi;  Li, Chaoying;  Han, Liwen;  Wang, Rongchun;  Wang, Shudan;  Chen, Haixia;  Liu, Kechun;  He, Chengwei
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Anti-angiogenesis  Anti-metastasis  Hepatocellular carcinoma cells  NF-κB/MMP-9/VEGF pathway  Polyphyllin VII  
Characterization of nanoparticles combining polyamine detection with photodynamic therapy Journal article
Communications Biology, 2021,Volume: 4,Issue: 1
Authors:  Li, Wenting;  Wang, Lingyun;  Sun, Tianlei;  Tang, Hao;  Bui, Brian;  Cao, Derong;  Wang, Ruibing;  Chen, Wei
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