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9R, the cholinesterase and amyloid beta aggregation dual inhibitor, as a multifunctional agent to improve cognitive deficit and neuropathology in the triple-transgenic Alzheimer's disease mouse model Journal article
Neuropharmacology, 2020,Volume: 181
Authors:  Ju,Yaojun;  Tam,Kin Yip
Favorite |  | TC[WOS]:1 TC[Scopus]:1 | Submit date:2021/03/04
Alzheimer's disease  Amyloid beta  Cholinesterase  Dual inhibition  Multifunction  
Yuan-Hu Zhi Tong Prescription Mitigates Tau Pathology and Alleviates Memory Deficiency in the Preclinical Models of Alzheimer’s Disease Journal article
Frontiers in Pharmacology, 2020,Volume: 11
Authors:  Iyaswamy,A.;  Krishnamoorthi,S. K.;  Liu,Y. W.;  Song,J. X.;  Kammala,A. K.;  Sreenivasmurthy,S. G.;  Malampati,S.;  Tong,B. C.K.;  Selvarasu,K.;  Cheung,K. H.;  Lu,J. H.;  Tan,J. Q.;  Huang,C. Y.;  Durairajan,S. S.K.;  Li,M.
Favorite |  | TC[WOS]:2 TC[Scopus]:1 | Submit date:2021/03/02
Alzheimer’s disease  Chinese medicine  connectivity map  microarray  neurofibrillary tangles  P301S tau mice  yuan-hu zhi tong  
An Isoquinolinium Dual Inhibitor of Cholinesterases and Amyloid β Aggregation Mitigates Neuropathological Changes in a Triple-Transgenic Mouse Model of Alzheimer's Disease Journal article
ACS Chemical Neuroscience, 2020,Volume: 11,Issue: 20,Page: 3346-3357
Authors:  Ju,Yaojun;  Chakravarty,Harapriya;  Tam,Kin Yip
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Alzheimer's disease  amyloid beta  cholinesterase  dual inhibition  
Shexiang Baoxin Pill, a Traditional Chinese Herbal Formula, Rescues the Cognitive Impairments in APP/PS1 Transgenic Mice Journal article
Frontiers in Pharmacology, 2020,Volume: 11
Authors:  Hu,Wei Hui;  Mak,Shing Hung;  Zheng,Zhong Yu;  Xia,Ying Jie;  Xu,Miranda Li;  Duan,Ran;  Dong,Tina Ting Xia;  Li,Shao Ping;  Zhan,Chang Sen;  Shang,Xiao Hui;  Tsim,Karl Wah Keung
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acetylcholinesterase  Alzheimer’s disease  Chinese medicine  cognitive enhancing effect  neuroprotective  Shexiang Baoxin Pill  
Human follicle-stimulating hormone ß subunit expression depends on FOXL2 and SMAD4 Journal article
Endocrinology (United States), 2020,Volume: 161,Issue: 5
Authors:  Ongaro,Luisina;  Schang,Gauthier;  Zhou,Ziyue;  Kumar,T. Rajendra;  Treier,Mathias;  Deng,Chu Xia;  Boehm,Ulrich;  Bernard,Daniel J.
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Activin  FOXL2  FSH  Gonadotrope  Pituitary  SMAD4  Transgene  
Oxyphylla a promotes degradation of α-synuclein for neuroprotection via activation of immunoproteasome Journal article
Aging and Disease, 2020,Volume: 11,Issue: 3,Page: 559-574
Authors:  Zhou,Hefeng;  Li,Shengnan;  Li,Chuwen;  Yang,Xuanjun;  Li,Haitao;  Zhong,Hanbing;  Lu,Jia Hong;  Lee,Simon Ming Yuen
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Degradation  Neuroprotection  Parkinson's disease  Proteasome  α-synuclein  
Fish oil protects the blood-brain barrier integrity in a mouse model of Alzheimer's disease Journal article
Chinese Medicine (United Kingdom), 2020,Volume: 15,Issue: 1
Authors:  Xie,Youna;  Yan,Lingli;  Zeng,Haitao;  Chen,Weineng;  Lu,Jia Hong;  Wan,Jian Bo;  Su,Huanxing;  Yao,Xiaoli
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Amyloid beta  Aβ-degrading enzymes  Neuroinflammation  NF-κB  Omega-3 polyunsaturated fatty acids  
Omega-3 polyunsaturated fatty acids promote brain-to-blood clearance of β-Amyloid in a mouse model with Alzheimer's disease Journal article
Brain, Behavior, and Immunity, 2020,Volume: 85,Page: 35-45
Authors:  Yan,Lingli;  Xie,Youna;  Satyanarayanan,Senthil Kumaran;  Zeng,Haitao;  Liu,Qiang;  Huang,Miaodan;  Ma,Yuemeng;  Wan,Jian Bo;  Yao,Xiaoli;  Su,Kuan Pin;  Su,Huanxing
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Alzheimer's disease  beta-Amyloid  Low-density lipoprotein receptor-related protein 1  Neuroinflammation  Omega-3 polyunsaturated fatty acids  
Tetramethylpyrazine Analogue T-006 Promotes the Clearance of Alpha-synuclein by Enhancing Proteasome Activity in Parkinson’s Disease Models Journal article
Neurotherapeutics, 2019,Volume: 16,Issue: 4,Page: 1225-1236
Authors:  Zhou,Hefeng;  Shao,Min;  Guo,Baojian;  Li,Chuwen;  Lu,Yucong;  Yang,Xuanjun;  ShengnanLi,;  Li,Haitao;  Zhu,Qi;  Zhong,Hanbing;  Wang,Yuqiang;  Zhang,Zaijun;  Lu,Jiahong;  Lee,Simon Ming Yuen
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Degradation  LMP7  Parkinson’s disease  Proteasome activity  α-synuclein  
Nitazoxanide, an anti-parasitic drug, efficiently ameliorates learning and memory impairments in AD model mice Journal article
ACTA PHARMACOLOGICA SINICA, 2019,Volume: 40,Issue: 10,Page: 1279-1291
Authors:  Lei Fan;  Xiao-xia Qiu;  Zhi-yuan Zhu;  Jian-lu Lv;  Jian Lu;  Fei Mao;  Jin Zhu;  Jia-ying Wang;  Xiao-wei Guan;  Jing Chen;  Jin Ren;  Ji-ming Ye;  Yong-hua Zhao;  Jian Li;  Xu Shen
Favorite |  | TC[WOS]:9 TC[Scopus]:11 | Submit date:2020/04/14
App/ps1 Transgenic Mice  Alzheimer’s Disease  Autophagy  Inflammation  Nitazoxanide