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Bromodomain and extra-terminal motif (BET) inhibition is synthetic lethal with loss of SMAD4 in colorectal cancer cells via restoring the loss of MYC repression Journal article
Oncogene, 2021,Volume: 40,Issue: 5,Page: 937-950
Authors:  Shi,Changxiang;  Yang,Eun Ju;  Liu,Yifan;  Mou,Pui Kei;  Ren,Guowen;  Shim,Joong Sup
Favorite |  | TC[WOS]:2 TC[Scopus]:2 | Submit date:2021/03/04
Cucurbituril-Oriented Nanoplatforms in Biomedical Applications Journal article
ACS Applied Bio Materials, 2020,Volume: 3,Issue: 12,Page: 8211-8240
Authors:  Cheng,Guowang;  Luo,Jingshan;  Liu,Yao;  Chen,Xiaojia;  Wu,Zhenfeng;  Chen,Tongkai
Favorite |  | TC[WOS]:1 TC[Scopus]:1 | Submit date:2021/03/02
Cancer Therapy  Cucurbiturils  Drug Delivery  Host-guest Systems  Supramolecular  
Clinical and Recent Patents Applications of PD-1/PD-L1 Targeting Immunotherapy in Cancer Treatment—Current Progress, Strategy, and Future Perspective Journal article
Frontiers in Immunology, 2020,Volume: 11
Authors:  Guo,Libin;  Wei,Ran;  Lin,Yao;  Kwok,Hang Fai
Favorite |  | TC[WOS]:9 TC[Scopus]:6 | Submit date:2021/03/04
clinical trial  immunotherapy  patent  PD-1  PD-L1  
Putting the Brakes on Tumorigenesis with Natural Products of Plant Origin: Insights into the Molecular Mechanisms of Actions and Immune Targets for Bladder Cancer Treatment Journal article
Cells, 2020,Volume: 9,Issue: 5
Authors:  Wu,Qiushuang;  Wong,Janet P.C.;  Kwok,Hang Fai
Favorite |  | TC[WOS]:2 TC[Scopus]:1 | Submit date:2021/03/04
apoptosis  bladder cancer  immunomolecular targets  natural products  plants  
In Vitro and MD Simulation Study to Explore Physicochemical Parameters for Antibacterial Peptide to Become Potent Anticancer Peptide Journal article
Molecular Therapy - Oncolytics, 2020,Volume: 16,Page: 7-19
Authors:  Ma,Rui;  Wong,Sin Wa;  Ge,Lilin;  Shaw,Chris;  Siu,Shirley W.I.;  Kwok,Hang Fai
Favorite |  | TC[WOS]:11 TC[Scopus]:11 | Submit date:2021/03/04
angiogenesis  anticancer peptides  antimicrobial peptides  apoptosis  drug discovery and development  molecular dynamics  targeted therapy  
Oral Colon-Targeted Konjac Glucomannan Hydrogel Constructed through Noncovalent Cross-Linking by Cucurbit[8]uril for Ulcerative Colitis Therapy Journal article
ACS Applied Bio Materials, 2020,Volume: 3,Issue: 1,Page: 10-19
Authors:  Ding,Yuan Fu;  Sun,Tianlei;  Li,Shengke;  Huang,Qiaoxian;  Yue,Ludan;  Zhu,Liangkui;  Wang,Ruibing
Favorite |  | TC[WOS]:8 TC[Scopus]:14 | Submit date:2021/03/02
Colitis  Controlled Drug Release  Cucurbituril  Host-guest Interactions  Konjac Glucomannan  
New opportunities and challenges of venom-based and bacteria-derived molecules for anticancer targeted therapy Journal article
Seminars in Cancer Biology, 2020
Authors:  Ma,Rui;  Kwok,Hang Fai
Favorite |  | TC[WOS]:0 TC[Scopus]:1 | Submit date:2021/03/04
Anticancer  Ion channels  Targeted therapy  Targets  Venom  
Cell Membrane Coating Technology: A Promising Strategy for Biomedical Applications Journal article
Nano-Micro Letters, 2019,Volume: 11,Issue: 1
Authors:  Liu,Yao;  Luo,Jingshan;  Chen,Xiaojia;  Liu,Wei;  Chen,Tongkai
Favorite |  | TC[WOS]:32 TC[Scopus]:39 | Submit date:2021/03/02
Biomimetic nanoparticles  Cancer therapy  Cell membrane  Detoxification  Immune modulation  
Assessment of chimeric antigen receptor T (CAR-T) cell cytotoxicity using droplet microflluidics Conference paper
23rd International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2019, Basel, 27.10.19 — 31.10.19
Authors:  Wang,Haitao;  Wong,Johnny Kuan Un;  Shi,Jingxuan;  Jia,Yanwei;  Deng,Chuxia;  Jiang,Lianmei;  Li,Peng;  Wong,Ada Hang Heng
Favorite |  | TC[WOS]:0 TC[Scopus]:0 | Submit date:2021/03/02
Car-t  Droplet Microfluidics  Immunotherapy  Precision Cancer Therapy  
Investigational hypoxia-activated prodrugs: Making sense of future development Journal article
Current Drug Targets, 2019,Volume: 20,Issue: 6,Page: 668-678
Authors:  Su,Min Xia;  Zhang,Le Le;  Huang,Zhang Jian;  Shi,Jia Jie;  Lu,Jin Jian
Favorite |  | TC[WOS]:2 TC[Scopus]:3 | Submit date:2021/03/02
Dna Alkylating Agents  Hypoxia-activated Prodrug  Patient Selection  Reductase Activity  Targeted Drugs  Topoisomerase Ii Inhibitors