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Andrographolide derivative as STAT3 inhibitor that protects acute liver damage in mice Journal article
BIOORGANIC & MEDICINAL CHEMISTRY, 2018,Volume: 26,Issue: 18,Page: 5053-5061
Authors:  Chen, Shao-Ru;  Li, Feng;  Ding, Mo-Yu;  Wang, Decai;  Zhao, Qi;  Wang, Yitao;  Zhou, Guo-Chun;  Wang, Ying
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Andrographolide  Stat3 Inhibitor  Acute Liver Damage  Inflammation  
Supramolecular strategy for reducing the cardiotoxicity of bedaquiline without compromising its antimycobacterial efficacy Conference paper
FOOD AND CHEMICAL TOXICOLOGY, Kunming, PEOPLES R CHINA, AUG 25-30, 2018
Authors:  Kuok, Kit Ieng;  Ng, Phoebe Choi In;  Ji, Xia;  Wang, Chunming;  Yew, Wing Wai;  Chan, Denise P. C.;  Zheng, Jun;  Lee, Simon M. Y.;  Wang, Ruibing
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Cucurbit[7]Uril  Bedaquiline  Supramolecular Formulation  Cardiotoxicity  Antimycobacterial  
Substantial protection against MPTP-associated Parkinson's neurotoxicity in vitro and in vivo by anti-cancer agent SU4312 via activation of MEF2D and inhibition of MAO-B Journal article
NEUROPHARMACOLOGY, 2017,Volume: 126,Page: 12-24
Authors:  Guo, Baojian;  Hu, Shengquan;  Zheng, Chengyou;  Wang, Hongyu;  Luo, Fangcheng;  Li, Haitao;  Cui, Wei;  Yang, Xifei;  Cui, Guozhen;  Mak, Shinghung;  Choi, Tony Chung-Lit;  Ma, Edmond Dik-Lung;  Wang, Yuqiang;  Lee, Simon Ming Yuen;  Zhang, Zaijun;  Han, Yifan
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Parkinson's disease  SU4312  Neuroprotection  Myocyte enhancer factor 2D  Monoamine oxidase-B  
Bioengineered three-dimensional co-culture of cancer cells and endothelial cells: A model system for dual analysis of tumor growth and angiogenesis Journal article
BIOTECHNOLOGY AND BIOENGINEERING, 2017,Volume: 114,Issue: 8,Page: 1865-1877
Authors:  Chiew, Geraldine Giap Ying;  Wei, Na;  Sultania, Samiksha;  Lim, Sierin;  Luo, Kathy Qian
Favorite |  | TC[WOS]:42 TC[Scopus]:42 | Submit date:2018/10/30
3d Co-culture  Angiogenesis  Liver Cancer  Endothelial Cells  Fret  Tumor Growth  
Co-delivery of paclitaxel and tetrandrine via iRGD peptide conjugated lipid-polymer hybrid nanoparticles overcome multidrug resistance in cancer cells Journal article
SCIENTIFIC REPORTS, 2017,Volume: 7
Authors:  Zhang, Jinming;  Wang, Lu;  Chan, Hon Fai;  Xie, Wei;  Chen, Sheng;  He, Chengwei;  Wang, Yitao;  Chen, Meiwan
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Digitoxin synergizes with sorafenib to inhibit hepatocelluar carcinoma cell growth without inhibiting cell migration Journal article
MOLECULAR MEDICINE REPORTS, 2017,Volume: 15,Issue: 2,Page: 941-947
Authors:  Xia, Yijun;  Yan, Wei;  Guo, Libin;  Meng, Chen;  Li, Bin;  Neves, Henrique;  Chen, Peng-Chen;  Li, Ling;  Huang, Yide;  Kwok, Hang Fai;  Lin, Yao
Favorite |  | TC[WOS]:8 TC[Scopus]:7 | Submit date:2018/10/30
Hepatocellular Carcinoma  Sorafenib  Digitoxin  Synergistic Inhibition  
Supramolecular alleviation of cardiotoxicity of a small-molecule kinase inhibitor Journal article
Organic and Biomolecular Chemistry, 2017,Volume: 15,Issue: 38,Page: 8046-8053
Authors:  Yang X.;  Huang Q.;  Bardelang D.;  Wang C.;  Lee S.M.Y.;  Wang R.
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Evaluation of the potential synergism of imatinib-related poly kinase inhibitors using growth factor stimulated proteoglycan synthesis as a model response Journal article
Journal of Pharmacy and Pharmacology, 2016,Volume: 68,Issue: 3,Page: 368-378
Authors:  Bernard R.;  Getachew R.;  Kamato D.;  Thach L.;  Osman N.;  Chan V.;  Zheng W.;  Little P.J.
Favorite |  | TC[WOS]:7 TC[Scopus]:7 | Submit date:2018/12/21
cell signalling  GAG hyperelongation  platelet derived growth factor  proteoglycan  tinibs  transforming growth factor-β  
Convection-enhanced delivery of sorafenib and suppression of tumor progression in a murine model of brain melanoma through the inhibition of signal transducer and activator of transcription 3 Journal article
JOURNAL OF NEUROSURGERY, 2016,Volume: 124,Issue: 5,Page: 1310-1318
Authors:  Zhaoxia Zou;  Yufang Yin;  Jenny Lin;  Li-chen J. Hsu;  Vanessa L. Brandon;  Fan Yang;  Richard Jove;  Rahul Jandial;  Gang Li;  Mike Y. Chen
Favorite |  | TC[WOS]:4 TC[Scopus]:4 | Submit date:2019/01/21
Sorafenib  Convection-enhanced Delivery  Stat3  Melanoma  Brain  Mice  Oncology  
iRGD decorated lipid-polymer hybrid nanoparticles for targeted co-delivery of doxorubicin and sorafenib to enhance anti-hepatocellular carcinoma efficacy Journal article
Nanomedicine: Nanotechnology, Biology, and Medicine, 2016,Volume: 12,Issue: 5,Page: 1303
Authors:  Zhang J.;  Hu J.;  Chan H.F.;  Skibba M.;  Liang G.;  Chen M.
Favorite |  | TC[WOS]:60 TC[Scopus]:63 | Submit date:2018/10/30
Active Targeting  Doxorubicin  Hepatocellular Carcinoma  Irgd Peptide  Sorafenib